EDITORIAL REVIEWS
Product Description The function of the heart is highly dependent on oxidative energy that is generated in mitochondria. Defects in mitochondrial structure and function can be found in association with cardiovascular diseases. Mitochondria and the Heart discusses the role that mitochondria plays in cardiovascular disease, including biogenesis and function of cardiac mitochondria during normal growth, development and aging. In addition, nonbioenergetic, biogenesis and degradation pathways are explored. Understanding these pathways and the effects that mitochondrial defects have in cardiac pathology is extremely important in establishing the diagnosis and treatment of mitochondrial-based cardiac diseases.
CUSTOMER REVIEWS (Average Customer Rating: 5.0 based on 1 review)
Top notch guide to mitochondrial medicine The topics covered in this book are timely and should prove of great interest to researchers of both clinical cardiology and studies of cardiac physiology, molecular medicine and mitochondrial bioenergetics. The background presentations concerning mitochondrial ROS generation and mitochondrial genetics are particularly well-organized, provide current information and offer significant insights into the role of mitochondria in apoptosis, cardioprotection and aging. Finally, the discussion of future applications of mitochondrial medicine forecasts the enormous potential of this promising avenue of research. September 13, 2005