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Pharmacogenomics in Drug Discovery and Development (Methods in Molecular Biology)


by Qing Yan

List Price: $99.50
Available: Usually ships in 24 hours
Sales Rank: 1066847
Studio: Humana Press
Binding: Hardcover
Number Of Pages: 487
Publication Date: March 19, 2008
Publisher: Humana Press


EDITORIAL REVIEWS

Product Description

Since each human is genetically distinctive, responding differently to disease-causing factors as well as drugs, the field pharmacogenomics arose to develop personalized medicine, or medicine that deals with the complexity of the human body. In Pharmacogenomics in Drug Discovery and Development, leading experts present methodical, state-of-the-art contributions covering topics from individual molecules to systemic diseases, examining both fundamental concepts and advanced technologies. Divided into three sections, the volume begins by exploring cutting-edge technologies used to pursue systems-based pharmacogenomics, followed by extensive chapters on gene-drug interactions and the use of pharmacogenomics in therapeutics of diseases.

Comprehensive and up-to-date, Pharmacogenomics in Drug Discovery and Development is an ideal volume for scientists striving to transform disease treatment into disease prevention.



CUSTOMER REVIEWS (Average Customer Rating: 5.0 based on 1 review)

A timely book on personalized medicine for all levels  
From fundamental concepts to advanced technologies in pharmacogenomics, this comprehensive book is useful for those interested in personalized medicine at all levels. The book discusses pharmacogenomics in three parts: technologies, molecules, and diseases and treatments. The first part of the book introduces cutting-edge technologies in pharmacogenomics, including bioinformatics, microarray, and association studies. The second part of the book discusses biomarkers and molecules including membrane transporters, receptors, and enzymes. This part includes three chapters on pharmacogenomics of G protein-coupled receptors (GPCR), providing a complete discussion on GPCR genetic variations, their relationships with diseases, and their potential uses as drug targets. The third part of this book focuses on diseases and treatments including psychiatric disorders, cardiovascular diseases, cancer, Alzheimer's disease, gastrointestinal disorders such as inflammatory bowel disease and irritable bowel syndrome, autoimmune diseases such as asthma and rheumatoid arthritis, and infectious diseases and vaccines.
June 18, 2008
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