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Molecular Imaging: Principles And Applications In Biomedical Research


by Markus Rudin

List Price: $157.00
Price: $110.00
You Save: $47.00 (30%)
Available: Usually ships in 24 hours
Sales Rank: 1160562
Studio: Imperial College Press
Binding: Hardcover
Number Of Pages: 564
Publication Date: August 01, 2005
Publisher: Imperial College Press


EDITORIAL REVIEWS

Product Description
Molecular imaging is a rapidly emerging field that translates many concepts developed for molecular biology and cellular imaging to the in vivo imaging of intact organisms. The technique allows the study of molecular biological events in their full context and will therefore become an indispensable tool for biomedical research and drug discovery and development. This volume familiarizes the reader with the concepts of imaging and molecular imaging in particular. Basic principles of imaging technologies, reporter moieties for the various imaging modalities and the design of target reporter constructs are described in the first part. The second part illustrates how these tools can be used to visualize relevant molecular events: the biodistribution of drugs/ligands, the expression of drug targets (receptors, enzymes), and the consequences of the molecular drug-target interactions (pathway activations, system responses). A final chapter deals with visualization of cell migration (cell therapies).


CUSTOMER REVIEWS (Average Customer Rating: 5.0 based on 1 review)

Summarizes the Current State of the Art  
It seems that with the ability to get any signal at all through a body, the modern day imaging systems can produce an image with useful information. In this book various signal generating systems (I guess you would call them) be it X-Ray tomography, magnetic resonance, and nuclear imaging are discussed.

This is followed with a discussion on the various techniques for reporting the images. Finally the book discusses the uses of these imaging techniques in examining the actions of drugs in living animals. These techniques are non-invasive so that what the drug is doing can be observed in real time. This is extremely important as getting the drug to the proper location in the patient where it can work is of the utmost in importance. Other uses of the technology are likewise discussed such as cell migration.

This book represents a good summary of the state of the art as it exists today and points in some of the directions that research is going in this rapidly emerging field.
March 10, 2006


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