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Mechanisms of Dietary Restriction in Aging and Disease (Interdisciplinary Topics in Gerontology)


by Charles V. Mobbs, Kelvin Yen, Patrick R. Hof

List Price: $188.00
Available: Usually ships in 24 hours
Sales Rank: 2475539
Studio: S. Karger AG (Switzerland)
Binding: Hardcover
Number Of Pages: 198
Publication Date: October 10, 2006
Publisher: S. Karger AG (Switzerland)


EDITORIAL REVIEWS

Product Description
Dietary restriction uniquely and robustly increases maximum lifespan and greatly reduces age-related diseases in many species, including yeast, flies, nematodes, and mammals. To study mechanisms mediating the protective effects of dietary restriction, the National Institute of Againg convened a program involving several leading gerontological laboratories. Results from many of these, as wellas from other leading researh institutions in the field, are presented in this book. The first three papers address general molecular mechanisms, derived in part from recent DNA microarry studies, that may medicate protective effects of dietary restriction. The subsquent articles examine specific model systems, including flies, nematodes and non-human primates, that have provided exciting new information about these mechanisms. Finally, mechanismsof dietary restriction mediating protective effects against cancer and neurological diseases are discussed. In addition to gerontologists and geriatricians, many other medical and nonmedical professionals in the field will find a great wealth of information on possible interventions that may ameliorate age-related diseases.
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