Product Description
There has been major growth in understanding immune suppression mechanisms and its relationship to cancer progression and therapy. This book highlights emerging new principles of immune suppression that drive cancer and it offers radically new ideas about how therapy can be improved by attacking these principles. Following work that firmly establishes immune escape as an essential trait of cancer, recent studies have now defined specific mechanisms of tumoral immune suppression. It also demonstrates how attacking tumors with molecular targeted therapeutics or traditional chemotherapeutic drugs can produce potent anti-tumor effects in preclinical models. This book provides basic, translational, and clinical cancer researchers an indispensable overview of immune escape as a critical trait in cancer and how applying specific combinations of immunotherapy and chemotherapy to attack this trait may radically improve the treatment of advanced disease. * Offers a synthesis of concepts that are useful to cancer immunologists and pharmacologists, who tend to work in disparate fields with little cross-communication* Drs Prendergast and Jaffee are internationally recognized leaders in cancer biology and immunology who have created a unique synthesis of fundamental and applied concepts in this important new area of cancer research* Summarizes the latest insights into how immune escape defines an essential trait of cancer* Includes numerous illustrations including: how molecular-targeted therapeutic drugs or traditional chemotherapy can be combined with immunotherapy to improve anti-tumor efficacy; and how reversing immune suppression by the tumor can cause tumor regression

CUSTOMER REVIEWS (Average Customer Rating: 5.0 based on 1 review)

Comprehensive review by Victoria A. Love (San Diego, CA)

5 Stars
November 29, 2007
When I first entered graduate school in 1999, I became interested in cancer immunology. My focus shifted slightly in the middle of my graduate program. Buying this book was a fantastic way to review older concepts and studies in the is field as well as quickly come up to date with current approaches and ideas. I highly recommend this text. It's also very well written and clearly organized.

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