| Design of Enzyme Inhibitors As Drugs: Volume 2 | Hardcoverby Merton Sandler (Editor), H. John Smith (Editor)
| List Price: | $165.00 | | | Available: | Usually ships in 24 hours |
| | Binding: | Hardcover | | Publisher: | Oxford University Press, USA | | Edition: | 1st Edition | | Page Count: | 848 Pages | | Publication Date: | May 26, 1994 | | Sales Rank: | 7,706,747th |
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FEATURES | - ISBN13: 9780192621344
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EDITORIAL REVIEWS |
Product Description
A high proportion of drugs currently coming to market exert their action in the body by inhibiting a target enzyme involved in a particular body function or in a bacterium, protozoon, or virus causing an infection. This book extends the previous volume in providing a comprehensive coverage of more recently recognized target enzymes and their known inhibitors and, within this framework of knowledge, demonstrates how the drug designer uses all available information to develop a specific therapeutic agent. Drug design is an interdisciplinary art; this text illustrates the pathway followed from the initial design concept and synthesis of an inhibitor, through its in vitro and in vivo assessments, to clinical trial -- a process involving chemists, biochemists, pharmacologists, and clinicians. |
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