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Neuropeptides: Regulators of Physiological Processes (Cellular and Molecular Neuroscience)
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Neuropeptides: Regulators of Physiological Processes (Cellular and Molecular Neuroscience) | Hardcover

by Fleur L. Strand (Author)

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Price:  $64.13
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Binding:  Hardcover
Publisher:  The MIT Press
Edition:  1st Edition
Page Count:  658 Pages
Publication Date:  January 11, 1999
Sales Rank:  461,998st


EDITORIAL REVIEWS


Product Description
In recent years there has been increasing interest and, subsequently, active research in neuropeptides. These neuroactive molecules coordinate, integrate, and regulate physiological processes in all organisms, throughout all phases of development. Acting as neurohormones, neurotransmitters, and/or neuromodulators, they maintain physiological homeostasis and influence important behavioral patterns. This textbook is the first to bring together and synthesize the neuropeptide research of the past decade in such a comprehensive, scholarly manner. The book is divided into two parts. In Part I the author defines the basic principles of neuropeptide action, including their biosynthesis, processing, transport, distribution, and interactions with receptors and second messenger systems. Strand also discusses the intimate interaction between the neuropeptides, stress, and the immune system. In Part II she discusses the regulatory functions of the families of neuropeptide in sufficient detail to provide both the advanced student and senior investigator with a thorough understanding of the most important neuropeptides. The text also contains a complete and up-to-date reference/reading list.


CUSTOMER REVIEWS (Average Customer Rating: 5.0 based on 8 reviews)

Neuropeptides: Reviewed by Abba Kastin 5 Stars
April 14, 2001
The Book "Neuropeptides: Regulators of Physiological Processes" is terrific. Not only does it provide the most comprehensive review of the field available anywhere , but it does so in an elegant style that remains amazingly easy to read. Moreover, the material is put together in such a way as to provide sophisticated new insights into the field.

Neuropeptides: Reviewed by Frank Antonawich 5 Stars
April 14, 2001
This book will clearly be considered the bible of the neuroendocrine field.

Neuropeptides: Reviewed by David de Wied 5 Stars
April 14, 2001
This book is a magnificent review of this fascinating subject. Strand presents a wealth of data in a very comprehensive manner. She has summarized the information in a scholarly yet highly lucid manner

Neuropeptide Regulators : Reviewed by Don Long 5 Stars
April 14, 2001
This book is a superb compilation of the complexities of the fields of neuropeptides. Portions of it are general enough to be of real value to any neuroscientist who wishes to understand more about this complex field. In its entirety the book offers an excellent summary which can be of use to anyone no matter how specialized or advanced in the neuropeptide field. The book begins with an excellent summary of the origins of neuropeptide theory, the discovery of the first of these transmitters, and a general summary of where we are today with the identification of this enormous group of peptides. For those beginning a career in research concerning neuropeptides, there is some excellent generalization of the techniques which are involved in discovering, quantifying and manipulating these neurotransmitters. The section on biosynthesis and action of neuropeptides is extremely well done and simple enough for anyone interested to understand, as is the description and localization of neuropeptides. The neuroendocrine system is presented in a very simple but complete form, and the section on the blood brain barrier brings anyone up to date in the function of the barrier transport system. Recpetors are described generally and then individual classes of receptors are described in great detail. This allows any specific group of receptors and any specific system to be investigated thoroughly. The book is well referenced. The illustrations and especially the schematic figures are exceptionally well done. All the pituitary peptides are thoroughly discussed and the literature surrounding them summarized. The section on the opiate neuropeptides is also well done, and then a number of peptideswhich are much less well known, particularly those that involve gut and other visceral functions are thoroughly discussed. The book is an invaluable resource. Anyone casually interested in the field can learn much by superficial perusal, but the real value will be in the thorough review of each topic which makes each individual chapter a valuable source for anyone wishing detailed information. This is really "must reading" for the graduate student interested in this field.

Editorial Review - Trends in Neurosciences 5 Stars
April 14, 2001
Given the complexity and rapid growth of research in neuropeptides it is perhaps not surprising that few texts have attempted to give an overview of this field. We should, therefore, be grateful to Fleur Strand for her well-written and comprehensive monograph. The author is an experienced neuroscientist who has been actively involved in research and teaching on the subject of neuropeptides, and the book is a coherent and readable volume that provides a great deal of valuable information to advanced students and others who are interested in neuropeptides. The book is well prepared with clear illustrations, and a comprehensive bibliography and index. The author provides an easily understood review of the many different experimental approaches needed to study the genes, receptors distribution, biosynthesis, release and actions of the neuropeptides. These include molecular neurobiology techniques, immunohistochemical-mapping procedures, the use of genetically engineered animals and studies of peptide actions at the cellular and systemic levels, using neurochemical, neurophysiological and behavioral analyses. A section on the relationship between neuropeptides, stress and the immune system is particularly well prepared, as is the explanation of the physiological roles of neuropeptides in the broader context of biology and evolution. Each chapter concludes with a detailed summary of the conclusions drawn, highlighting the main concepts, which makes for easy review. A concluding section on invertebrate neuropeptides again mixes peptides of neural and non-neural origin but provides a valuable overview of the evolution and biological importance of peptides as chemical signalling molecules.

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