| View Larger Image | Introduction to Macromolecular Crystallography | Paperbackby Alexander McPherson (Author)
| List Price: | $89.95 | | Price: | $78.58 | | You Save: | $11.37 (13%) | | | Available: | Usually ships in 24 hours |
| | Binding: | Paperback | | Publisher: | Wiley-Blackwell | | Edition: | 2nd Edition | | Page Count: | 283 Pages | | Publication Date: | February 03, 2009 | | Sales Rank: | 108,229th |
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EDITORIAL REVIEWS |
Product Description
A comprehensive and approachable introduction to crystallography — now updated in a valuable new edition The Second Edition of this well-received book continues to offer the most concise, authoritative, and easy-to-follow introduction to the field of crystallography. Dedicated to providing a complete, basic presentation of the subject that does not assume a background in physics or math, the book's content flows logically from basic principles to methods, such as those for solving phase problems, interpretation of Patterson maps and the difference Fourier method, the fundamental theory of diffraction and the properties of crystals, and applications in determining macromolecular structure. This new edition includes a vast amount of carefully updated materials, as well as two completely new chapters on recording and compiling X-ray data and growing crystals of proteins and other macromolecules. Richly illustrated throughout to clarify difficult concepts, this book takes a non-technical approach to crystallography that is ideal for professionals and graduate students in structural biology, biophysics, biochemistry, and molecular biology who are studying the subject for the first time. |
CUSTOMER REVIEWS (Average Customer Rating: 4.5 based on 6 reviews)
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basic knowledge in the subject by mjare  5 Stars
June 14, 2009
This is a very usefull book especially for the beginners in the field of macromolecular crystallography. Bases of crystallography are almost perfectly explained in this small book. This book can be regarded as a ''road map'' for the beginners, because it shows what details reader should know as a minimum.
More advaced reader can use it as a small ''review-textbook''.
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Glaring Errors, how has no one noticed? by Sean (RI)  2 Stars
January 08, 2009
I'm honestly a bit concerned that none of the professional reviews have brought this up; but there are some huge misrepresentations of wave/optical physics that occur in this book. Fortunately, these are all in the introductory chapters, which explain the physics of waves and diffraction for systems of points and planes, with the latter chapters (the ones that are arguably unique to this sort of book) generally error free, so that a person using this as an intro text will surely understand the methodology of x-ray crystallography and how to interpret a diffraction pattern. It's really unfortunate, however, how much of the beginning "background" is completely incorrect. Dr. McPherson writes that the electric and magnetic fields which constitute an electromagnetic wave are out of phase, such that the E field is maximum when the H is zero, and vice-versa. This is wrong: E and B are completely in phase and orthogonal, and while H's phase can meander depending on the medium, it is surely not universally 90 degrees, and certainly has nothing to do with conservation of energy, which is suggested in this book. Also, while a small error; he suggests that a dot product of two vectors is equal to the projection of one on the other, and vice-versa. He never mentions dividing by magnitude (or starting with unit vectors), and as such all of the arguments of his trig/exponential functions within Fourier transformations aren't dimensionless, which is mathematically incorrect and physically meaningless. While this may seem like a small error; as this book is meant for "biochemist, molecular biologists, and pharmacolgical scientists," any student who tries to walk page by page through the physics to understand crystallography will surely think the book is inconsistent, but will probably assume one's own incompetence and inability to grasp the concepts.
It seems as though this book must have been written by a biologist (not a physicist) who generally remembers his vector algebra and optics from undergrad but didn't bother to review or check any sources. I can't completely slam the book, as the last chapters are helpful on interpreting raw data, but as an intro text, how is this an excusable product?
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Highly Recommended 5 Stars
September 03, 2003
"...I highly recommend this book...in fact, I foresee it finding its way to the bookshelves of many faculty members, albeit with frequent removal for consultation as an educational tool!" (Clinical Chemistry, Vol. 49, No. 7, 2003)
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Recommended Book 5 Stars
May 14, 2003
"...this welcome addition to the introductory crystallographic literature should be well received...recommended..." (Choice, Vol. 40, No. 8, April 2003)
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Excellent 5 Stars
May 14, 2003
"...an excellent introductory text..." (Journal of Proteome Research, Vol. 2, No. 2, March/April 2003)
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SIMILAR PRODUCTS |
| Crystallography Made Crystal Clear, Third Edition: A Guide for Users of Macromolecular Models (Complementary Science)
by Gale Rhodes (Author)
Crystallography Made Crystal Clear makes crystallography accessible to readers who have no prior knowledge of the field or its mathematical basis. This is the most comprehensive and concise reference for beginning Macromolecular crystallographers, written by a leading expert in the field. Rhodes' uses visual and geometric models to help readers understand the mathematics that form the basis of x-ray crystallography. He has invested a great deal of time and effort on World Wide Web tools for...
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| Outline of Crystallography for Biologists
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Outline of Crystallography for Biologists is intended for researchers and students in the biological sciences who require an insight into the methods of X-ray crystallography without needing to learn all the relevant theory. The main text is purely descriptive and is readable by those with minimal mathematical knowledge. Some mathematical detail is given throughout in boxes, but these can be ignored. Theory is limited to the essentials required to comprehend issues of quality. There is an...
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| Principles of Protein X-Ray Crystallography (Springer Advanced Texts in Chemistry)
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X-ray crystallography has long been a vital method for studying the structure of proteins and other macromolecules. As the importance of proteins continues to grow, in fields from biochemistry and biophysics to pharmaceutical development and biotechnology, many researchers have found that a knowledge of X-ray diffraction is an indispensable tool. In this new edition of his essential work, Dr. Jan Drenth, recognized internationally for his numerous contributions to crystallographic research, has...
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| Protein Crystallization, Second Edition (IUL Biotechnology Series)
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Completely revised and updated, Protein Crystallization, 2nd Edition is a greatly expanded follow-up to the best-selling 1st edition. Completely new chapters on high-throughput methods, mass spectrometry, microcalorimetry, counterdiffusion, heavy-atom derivatization, selenomethionine-labeling, rational strategies for crystallization, and protein modification to improve crystallization. Updated chapters on formulation of the protein before crystallization, characterization of the protein by...
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| Protein Crystallography: A Concise Guide
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The proteome remains a mysterious realm. Researchers have determined the structures of only a small fraction of the proteins encoded by the human genome. Crystallography continues to be the primary method used to determine the structures of the remaining unknown proteins. This imaging technique uses the diffraction of X-rays to determine a protein's three-dimensional molecular structure. Drawing on years of research and teaching experience, Eaton E. Lattman and Patrick J. Loll use...
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