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| View Larger Image | Mass Spectrometry in Biophysics : Conformation and Dynamics of Biomolecules | Hardcoverby Igor A. Kaltashov (Author), Stephen J. Eyles (Author)
| List Price: | $115.00 | | | Available: | Usually ships in 24 hours |
| | Binding: | Hardcover | | Publisher: | Wiley-Interscience | | Edition: | 1st Edition | | Page Count: | 474 Pages | | Publication Date: | April 21, 2005 | | Sales Rank: | 2,171,662nd |
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EDITORIAL REVIEWS |
Product Description
The first systematic summary of biophysical mass spectrometry techniques Recent advances in mass spectrometry (MS) have pushed the frontiers of analytical chemistry into the biophysical laboratory. As a result, the biophysical community's acceptance of MS-based methods, used to study protein higher-order structure and dynamics, has accelerated the expansion of biophysical MS. Despite this growing trend, until now no single text has presented the full array of MS-based experimental techniques and strategies for biophysics. Mass Spectrometry in Biophysics expertly closes this gap in the literature. Covering the theoretical background and technical aspects of each method, this much-needed reference offers an unparalleled overview of the current state of biophysical MS. Mass Spectrometry in Biophysics begins with a helpful discussion of general biophysical concepts and MS-related techniques. Subsequent chapters address: * Modern spectrometric hardware * High-order structure and dynamics as probed by various MS-based methods * Techniques used to study structure and behavior of non-native protein states that become populated under denaturing conditions * Kinetic aspects of protein folding and enzyme catalysis * MS-based methods used to extract quantitative information on protein-ligand interactions * Relation of MS-based techniques to other experimental tools * Biomolecular properties in the gas phase Fully referenced and containing a helpful appendix on the physics of electrospray mass spectrometry, Mass Spectrometry in Biophysics also offers a compelling look at the current challenges facing biomolecular MS and the potential applications that will likely shape its future. |
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