Product Description
Knowledge of the blood-brain barrier forms an essential component in the understanding of a large proportion of medical disciplines. Nevertheless, ignorance in this field still impedes progress in many areas, including cerebrovascular disease, Alzheimer's disease, cerebral AIDS, brain tumors, and the development of effective new neuropharmaceuticals. This introduction for both researchers and clinicians across the medical sciences is intended to aid both those beginning work directly in this area and those wishing simply to be better informed when interpreting information where the blood-brain barrier may be involved. Recent advances in both methodology and biology are detailed in fifty state-of-the-art chapters written by international authorities.

SIMILAR PRODUCTS

	The Blood-Brain Barrier and Its Microenvironment: Basic Physiology to Neurological Disease by Elga de Vries (Editor), Alexandre Prat (Editor) This reference analyzes the cellular and molecular biology and mechanisms of the blood-brain barrier (BBB) and presents the most recent studies on the role of the BBB in the development and initiation of a wide range of physiological and pathological conditions affecting the central nervous system.
	Blood'Brain Barrier: Biology and Research Protocols (Methods in Molecular Medicine) by Sukriti Nag (Editor) Univ. of Toronto, Canada. Text provides the details of selected morphologic, permeability, transport, in vitro, and molecular techniques for BBB studies. Each part is preceded by a review emphasizing the advantages and pitfalls of particular techniques. Written for researchers in BBB. DNLM: Blood--Brain Barrier--physiology.
	The Blood-Brain Barrier and Drug Delivery to the CNS by Michael Bradbury (Editor), David Begley (Editor), Jorg Kreuter (Editor) King's College, London, UK. Addresses how to determine drug permeability across the blood-brain barrier more effectively. Focuses on physiological mechanisms influencing the passage of agents into the brain and covers the latest research, problems and solutions, existing strategies, and prospects for future research. For researchers. Expanded-outline format.
	Blood-Brain Barriers: From Ontogeny to Artificial Interfaces(2 volume set) by Rolf Dermietzel (Editor), David C. Spray (Editor), Maiken Nedergaard (Editor) This first handbook to integrate developmental and cellular aspects combines the different structural and functional features involved in the regulation of brain perfusion and neuronal function. It highlights pharmacological and biomedical applications with sections on drug delivery and disease-related states as well as explaining in detail the role of astrocytes, shown to be an essential link between neurons and cerebral blood vessels. In addition the book studies how the structural elements...
	Drug-like Properties: Concepts, Structure Design and Methods: from ADME to Toxicity Optimization by Edward Kerns (Author), Li Di (Author) Of the thousands of novel compounds that a drug discovery project team invents and that bind to the therapeutic target, typically only a fraction of these have sufficient ADME/Tox properties to become a drug product. Understanding ADME/Tox is critical for all drug researchers, owing to its increasing importance in advancing high quality candidates to clinical studies and the processes of drug discovery. If the properties are weak, the candidate will have a high risk of failure or be less...