| View Larger Image | Systems Biology: Principles, Methods, and Concepts | Hardcoverby A.K. Konopka (Editor)
| List Price: | $73.95 | | Price: | $63.22 | | You Save: | $10.73 (15%) | | | Available: | Usually ships in 24 hours |
| | Binding: | Hardcover | | Publisher: | CRC | | Edition: | 1st Edition | | Page Count: | 256 Pages | | Publication Date: | November 20, 2006 | | Sales Rank: | 769,449th |
|
ACCESSORIES |
| | Practical Guide to Protein Bioinformatics: Sequence, Structure and Function (Chapman & Hall/ CRC Mathematical Biology & Medicine)
by Shoba Ranganathan (Author)
While there are many textbooks available that provide all the information bench scientists, researchers, and students need to carry out "wet" laboratory experiments, very few sufficiently address computer-based functional annotation. Furthermore, most books on bioinformatics and computational biology focus on the genomic DNA aspects and all but overlook the vast and important area of protein bioinformatics. This book fills those gaps. It provides a comprehensive introduction to the...
| 
| An Introduction to Systems Biology: Design Principles of Biological Circuits (Chapman & Hall/CRC Mathematical & Computational Biology)
by Uri Alon (Author)
Thorough and accessible, this book presents the design principles of biological systems, and highlights the recurring circuit elements that make up biological networks. It provides a simple mathematical framework which can be used to understand and even design biological circuits. The textavoids specialist terms, focusing instead on several well-studied biological systems that concisely demonstrate key principles. An Introduction to Systems Biology: Design Principles of Biological...
| 
| Stochastic Modelling for Systems Biology (Mathematical and Computational Biology)
by Darren J. Wilkinson (Author)
Although stochastic kinetic models are increasingly accepted as the best way to represent and simulate genetic and biochemical networks, most researchers in the field have limited knowledge of stochastic process theory. The stochastic processes formalism provides a beautiful, elegant, and coherent foundation for chemical kinetics and there is a wealth of associated theory every bit as powerful and elegant as that for conventional continuous deterministic models. The time is right for an...
|
|
EDITORIAL REVIEWS |
Product Description
With extraordinary clarity,the Systems Biology: Principles, Methods, and Concepts focuses on the technical practical aspects of modeling complex or organic general systems. It also provides in-depth coverage of modeling biochemical, thermodynamic, engineering, and ecological systems. Among other methods and concepts based in logic, computer science, and dynamical systems, it explores pragmatic techniques of General Systems Theory. This text presents biology as an autonomous science from the perspective of fundamental modeling techniques. A complete resource for anyone interested in biology as an exact science, it includes a comprehensive survey, review, and critique of concepts and methods in Systems Biology. |
CUSTOMER REVIEWS (Average Customer Rating: 4.0 based on 7 reviews)
|
Most interesting! Terrific text for experts and novices alike. by Margaret J  5 Stars
July 26, 2009
I am impressed by the depth and skills with which difficult topics are handled by the authors of individual chapters as well as by the Editor. Introductory chapter 1 is indeed a state-of-the-art vision of systems biology for today's biologists, chemists, and engineers. The entire book is masterfully written by most competent experts and academic teachers available today. Notably the chapter about chaos (Chapter 6) is the best text on the topic I have read thus far in my long life (I'm not very young and I've read scores of publications about non-linear phenomena.) Chapters written under the leadership of Prof. Salamon (Chapters 3 and 9) are most convincing texts about macroscopic thermodynamics that are accessible to general readers as well as to the experts. (I guess Chapter 9 is for the experts because of the required mathematical background.) Biochemical Systems Theory is a subject of Chapter 2, which in itself is an interesting text in systems biochemistry including its (long) history. Chapter 5 introduces a concept of organic system, while discussing problems of ecological networks. This notion (organic system) is of great importance for systems biology because not every organic system needs to be a living entity. From the point of view of scientific method, organic properties (of organic systems) can be treated by the techniques analogous to dynamic systems but the organic properties (initial and boundary conditions) are not compatible with those known from physics. In a way organic systems could be a methodological bridge between classical science and modern systems biology. The remaining chapters cover engineering aspects of systems biology (chapters 6 and 7) as well as a history of philosophical investigations relevant to life sciences (Chapter 4.)
The book is very much worth reading by anyone interested in science (particularly in biology.)
| |
Systems Biology: really good and serious book on the subject by Christopher N 5 Stars
July 12, 2009
This edited book is remarkably well written and informative. The Editor (Dr. Konopka) and the publishers (CRC Press) definitely went an extra mile to assure a comprehensive coverage of today's foundations of life science. Unlike a vast majority of books with "systems biology" in the title, this monograph authoritatively grasps and describes contributing methods that have for over 2000 years differentiated studies of life from other fields of science. The understandable disappointment of biologists with implanting physics into biology (see for instance Life Itself: A Comprehensive Inquiry into the Nature, Origin, and Fabrication of Life (Complexity in Ecological Systems) or This Is Biology: The Science of the Living WorldWhat Makes Biology Unique?: Considerations on the Autonomy of a Scientific Discipline (Law in Context S.)) has been addressed in this book with great scientific precision. This in turn makes this relatively short book a fascinating reading not only for biologists. It should also be recommended to all intelligent readers who like to ask questions and who don't accept trivial answers. If you search for an adequate definition of Systems Biology, read this book in detail. It does define the field and it does explain why the non-reductionist systems view of the living world is a popular topic of scientific research today.
| |
Really good book on the topic by A. Ciapata 5 Stars
July 05, 2009
This is an important book (I agree with another reviewer about this.) It covers all needed foundations of today's systems biology in a non-trivial way. It also contains a definitive guidance on terminology of systems theory and relational biology; something most other books with "systems biology" in the title are missing. It is true that (perhaps intentionally) the use of networks is only emphasized in one chapter (Chapter 5)while the ideas from thermodynamics, general systems theory and relational biology are explained in detail in several other chapters. That's why (I agree again with another reviewer) readers of this book who wish to study systems biology could greatly benefit from a supplementary reading of a good text on networks. On the other hand readers with some expertise in science and those who are familiar with networks will likely find a lot of intellectual satisfaction from reading this relatively short book from cover to cover.
| |
Systems biology well defined! by Michael G 5 Stars
July 03, 2009
This is an outstanding book that should be recommended to the beginners and experts alike. Written by top scientists in the sub-fields that contribute to today's systems biology, the book is one of very few scientific celebrations of NON-REDUCTIONIST methods of usable in life sciences. It is also a very original attempt to present foundations of biology from a perspective of today's systems theory and computer science. For the readers who would like to seriously study systems biology I would recommend reading this volume together with one of a number of solid texts on network methodology (I personally favor an excellent book by Palsson Systems Biology: Properties of Reconstructed Networks as such companion text.)
| |
Outstanding state-of-the-art text-handbook-monograph in one short volume by Hubert from Baltimore 5 Stars
June 30, 2009
This text should be recommended to every student of systems biology and, for that matter, to most practicing biologists who are interested in profound understanding of systems methodology in life sciences. The book focuses on and explores the very foundations of modeling complex organic systems from the perspectives that in the past were called "cybernetics", "systems science", "General Systems Theory", or "Relational Biology". It does however contain two state-of-the-art chapters on thermodynamics, one on biochemical kinetics, and one on non-linear dynamics; topics that are also covered in a number of other systems biology books. The methodology of dealing with networks is covered as well but to a lesser extent than in many other systems biology texts. The glossary of terms from a variety of different fields that contribute to systems biology is also included, such that the book can be used by self-learners.
Overall the book is a great achievement of a group of world-class top experts who contributed definitive chapters in their respective sub-fields of systems biology. I highly recommend this text as a valuable reading for all readers who wish to understand the phenomenon of life itself from a scientific point of view.
| |
SIMILAR PRODUCTS |
| An Introduction to Systems Biology: Design Principles of Biological Circuits (Chapman & Hall/CRC Mathematical & Computational Biology)
by Uri Alon (Author)
Thorough and accessible, this book presents the design principles of biological systems, and highlights the recurring circuit elements that make up biological networks. It provides a simple mathematical framework which can be used to understand and even design biological circuits. The textavoids specialist terms, focusing instead on several well-studied biological systems that concisely demonstrate key principles. An Introduction to Systems Biology: Design Principles of Biological...
| 
| Mathematical Models in Biology (Classics in Applied Mathematics)
by Leah Edelstein-Keshet (Author)
Mathematical Models in Biology is an introductory book for readers interested in biological applications of mathematics and modeling in biology. A favorite in the mathematical biology community since its first publication in 1988, the book shows how relatively simple mathematics can be applied to a variety of models to draw interesting conclusions. Connections are made between diverse biological examples linked by common mathematical themes. A variety of discrete and continuous ordinary and...
| 
| System Modeling in Cellular Biology: From Concepts to Nuts and Bolts
by Zoltan Szallasi (Editor), Jörg Stelling (Editor), Vipul Periwal (Editor)
Research in systems biology requires the collaboration of researchers from diverse backgrounds, including biology, computer science, mathematics, statistics, physics, and biochemistry. These collaborations, necessary because of the enormous breadth of background needed for research in this field, can be hindered by differing understandings of the limitations and applicability of techniques and concerns from different disciplines. This comprehensive introduction and overview of system modeling...
| 
| Systems Biology: Volume I: Genomics (Series in Systems Biology)
by Isidore Rigoutsos (Editor), Gregory Stephanopoulos (Editor)
The advent of genome sequencing and associated technologies has transformed biologists' ability to measure important classes of molecules and their interactions. This expanded cellular view has opened the field to thousands of interactions that previously were outside the researchers' reach. The processing and interpretation of these new vast quantities of interconnected data call for sophisticated mathematical models and computational methods. Systems biology meets this need by combining...
| 
| Systems Biology: Properties of Reconstructed Networks
by Bernhard O. Palsson (Author)
Genome sequences are now available that enable us to determine the biological components that make up a cell or an organism. The new discipline of systems biology examines how these components interact and form networks, and how the networks generate whole cell functions corresponding to observable phenotypes. This textbook describes how to model networks, determine their properties, and relate these to phenotypic functions. Some knowledge of linear algebra and biochemistry is required, since...
|
|
|
