| View Larger Image | Treatments from Toxins: The Therapeutic Potential of Clostridial Neurotoxins | Hardcoverby Keith Alan Foster (Editor), Peter Hambleton (Editor), Clifford C. Shone (Editor)
| List Price: | $209.95 | | | Available: | Usually ships in 24 hours |
| | Binding: | Hardcover | | Publisher: | CRC | | Edition: | 1st Edition | | Page Count: | 312 Pages | | Publication Date: | November 02, 2006 | | Sales Rank: | 2,993,959nd |
|
ACCESSORIES |
| Chimeric Toxins: Mechanisms of Action and Therapeutic Applications (Cellular and Molecular Mechanisms of Toxin Action)
by Haya Lorberboum-Galski (Editor), Philip Lazarovici (Editor)
Bacteria and plants produce powerful toxins that can cause a variety of diseases, some of which are lethal for many animal species. Because of their potency in killing eukaryotic cells, they have been used in the development of novel agents for targeted immunotherapy, and have been termed 'chimeric toxins'. Understanding these mechanisms will open new avenues for the design of novel therapies for the treatment of toxin-related diseases. In this book, the authors review the structure, function...
| 
| The Role of Glia in Neurotoxicity, Second Edition
by Michael Aschner (Editor), Lucio G. Costa (Editor)
Presenting the latest research in glial cell function gleaned from new techniques in imaging and molecular biology, The Role of Glia in Neurotoxicity, Second Edition covers multiple aspects of glial cells, including morphology, physiology, pharmacology, biochemistry, pathology, and their involvement in the pathophysiology of neurological diseases. The book is structured to examine the interactions between glial cells and neurons during development, adulthood, and senescence, followed by...
| 
| Handbook on Clostridia
by Peter Duerre (Editor)
Clostridia is one of the largest bacterial genera with an enormous potential for biotechnical and medical applications. Despite this scientific, medical, and industrial interest, information on basic methods, biochemical fundamentals, clinical practice, industrial applications, and novel developments is scattered in a variety of research articles, reviews, and book chapters. The Handbook on Clostridia combines all these topics in a single volume. The author has taken a global approach,...
|
|
EDITORIAL REVIEWS |
Product Description
As little as two decades ago, deliberately injecting botulinum toxin into patients would have seemed foolhardy at best and criminal at worst. The increased clinical use of botulinum toxins has expanded the body of knowledge available on the structure and function of these proteins. This knowledge can be applied to topics as varied as therapies based on the endopeptidase activity of the toxins, vaccine development, protection against botulism, and vectors for neuronal drug delivery. Based on recent scientific and clinical information from top international authorities, Treatments from Toxins: The Therapeutic Potential of Clostridial Neurotoxins reviews the status of current research and development and identifies significant developments. Drawing on their vast experience in this field, the editors present the basic background of the bacteriology and genetics of the neurotoxigenic clostridia, a history of the discovery of the neurotoxins, and an overview of the tetanus and botulism diseases. The chapters detailing common medical applications of the toxins cover side effects and novel uses, including neuronal drug delivery strategies, and provide a fresh look at what can still be achieved. They also explore the toxins as potential threat agents and the advent of the therapeutic use of botulinum toxins. Highlighting the pitfalls, successes, and challenges that exist when engineering complex proteins, the book brings together the clinical and theoretical worlds. It presents a broad overview of the current status of botulinum research and its clinical applications. |
|
