| View Larger Image | Nuclear Localization of Growth Factors and of Monoclonal Antibodies | Hardcoverby Ewa Rakowicz-Szulczynska (Author)
| List Price: | $249.95 | |
| | Binding: | Hardcover | | Publisher: | CRC | | Edition: | 1st Edition | | Page Count: | 224 Pages | | Publication Date: | October 13, 1993 | | Sales Rank: | 7,347,364th |
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EDITORIAL REVIEWS |
Product Description
Nuclear Localization of Growth Factors and of Monoclonal Antibodies focuses on how an additional class of chromatin receptors is directly involved in mediation of the action of growth factors on the gene regulation level. The book describes a new intracellular pathway of growth factors and presents methods for identifying nuclear antigens with an epitopic homology of the cell surface antigens. It teaches how to distinguish monoclonal antibodies that penetrate the cell and localize in the nucleus from those that act only on the cell surface. New light is shed on the mechanisms of malignant transformation, and new approaches to developing anti-cancer and anti-HIV drugs are covered. The book will be important for oncologists, biochemists, cell biologists, pharmaceutical researchers, investigative pathologists, neurochemists, and immunologists. |
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