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Intracellular Calcium-Dependent Proteolysis
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Intracellular Calcium-Dependent Proteolysis | Hardcover

by Ronald L. Mellgren (Author), Takashi Murachi (Author)

List Price: $309.95  

Binding:  Hardcover
Publisher:  CRC
Edition:  1st Edition
Page Count:  304 Pages
Publication Date:  August 29, 1990
Sales Rank:  7,830,723th


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Product Description
Intracellular Calcium-Dependent Proteolysis explains what is now known about calpains, which are intracellular, non-lysosomal enzymes involved in intracellular protein catabolism. The book provides a comprehensive overview of topics ranging from the molecular biology of the calpains and their specific inhibitor protein (calpastatin) to physiologic and pathologic consequences of the presence of this proteolytic system in many model cells and tissues. Several theoretical functions of the calpains are discussed, including their potential roles in muscle protein turnover, platelet activation, membrane fusion, and synaptic plasticity. Intracellular Calcium-Dependent Proteolysis is a valuable source of information for researchers and students interested in the regulation of intracellular protein catabolism and the general effects of Ca2+ on cell function.
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