| P53 Suppressor Gene (Molecular Biology Intelligence Unit) | Hardcoverby Tapas Mukhopadhyay (Author), Steven A. Maxwell (Author), Jack A. Roth (Author)
| List Price: | $69.00 | | | Available: | Temporarily out of stock. Order now and we'll deliver when available. We'll e-mail you with an estimated delivery date as soon as we have more information. Your credit card will not be charged until we ship the item. |
| | Binding: | Hardcover | | Publisher: | Springer | | Page Count: | 129 Pages | | Publication Date: | April 01, 1995 | | Sales Rank: | 7,899,558th |
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EDITORIAL REVIEWS |
Product Description
This book is about the p53 gene, one of the most frequently mutated or deleted genes in human cancers. The frequent occurrence of inactivated p53 implicates this gene product in the genesis of many human cancers. The p53 gene can suppress the growth of cancer cells and the transformation process by oncogenes. The p53 protein is a transcription factor that can repress or activate promoters containing one of three p53 DNA-binding motifs. The activity of p53 is regulated by phosphorylation and other transcription factors. Replacement of the p53 function or restoration of the p53 biochemical pathway is a focus of gene therapy. |
CUSTOMER REVIEWS (Average Customer Rating: 5.0 based on 1 review)
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p53 AND THE HCV  5 Stars
February 02, 1999
tumor supressor gene. is a proliferating gene and is contolloing the cell division. I want now the relationship between the HCV infection and the p53 mutation.
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