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| View Larger Image | Regulation of Gene Expression | Hardcoverby Gary H. Perdew (Author), Jack P. Vanden Heuvel (Author), Jeffrey M. Peters (Author)
| List Price: | $139.00 | | | Available: | Usually ships in 24 hours |
| | Binding: | Hardcover | | Publisher: | Humana Press | | Edition: | 1st Edition | | Page Count: | 344 Pages | | Publication Date: | September 15, 2006 | | Sales Rank: | 1,306,420st |
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EDITORIAL REVIEWS |
Product Description
Regulation of Gene Expression: Molecular Mechanisms presents a comprehensive overview of methods and approaches for characterizing mechanisms of gene regulation. The text is appropriate both as a graduate textbook and a standard laboratory reference and provides the essential groundwork for an advanced understanding of the various mechanisms that may result in altered activity of a specific cell protein. Each of three sections explores mechanisms of gene regulation and expression, and presents methods and protocols for achieving specific experimental goals. Part I focuses on approaches for studying control of mRNA expression and determining target genes for a given transcription copy. Part II outlines the methods for determining how proteins can regulate each other by mediating synthesis, degradation, protein-protein interactions, and posttranslational modification. Part III explores how gene targeting techniques in mice can provide insight into protein function. This volume provides a clear, concise overview of the protocols and techniques used to examine chemically or disease-mediated alterations in gene expression in mammalian systems. |
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