| View Larger Image | Protein'Ligand Interactions: Methods and Applications (Methods in Molecular Biology) | Hardcoverby G. Ulrich Nienhaus (Editor)
| List Price: | $159.00 | |
| | Binding: | Hardcover | | Publisher: | Humana Press | | Edition: | 1st Edition | | Page Count: | 580 Pages | | Publication Date: | March 21, 2005 | | Sales Rank: | 2,049,268nd |
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EDITORIAL REVIEWS |
Product Description
A readily reproducible collection of established and emerging techniques for studying the interaction between proteins and ligands, including biochemical/bulk techniques, structure analysis, spectroscopy, single-molecule studies, and theoretical/computational tools. Among the highlights are surface plasmon resonance (SPR) and reflectometric biosensor approaches, high-throughput screening with confocal optics microscopy, single molecule fluorescence and fluorescence correlation spectroscopy (FCS), atomic force microscopy (AFM), crystallography of reaction intermediates, and time-resolved x-ray crystallography. The protocols follow the successful Methods in Molecular Biology™ series format, each offering step-by-step laboratory instructions, an introduction outlining the principle behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls. |
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