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| View Larger Image | DNA Repair Protocols (Methods in Molecular Biology) | Hardcoverby Daryl S. Henderson (Editor)
| List Price: | $135.00 | | | Available: | Usually ships in 24 hours |
| | Binding: | Hardcover | | Publisher: | Humana Press | | Edition: | 2ndnd Edition | | Page Count: | 512 Pages | | Publication Date: | October 01, 2005 | | Sales Rank: | 1,953,581st |
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EDITORIAL REVIEWS | Product Description This collection of readily reproducible techniques for repairing mammalian DNA contains fourteen entirely new chapters and many extensively revised chapters. The methods presented cover cytogenetic analysis, measuring the cellular response to ionizing radiation, detecting single-strand (nicks) and double-strand DNA breaks, detecting the presence of "adducted" bases in DNA, and preparing mismatch repair (MMR) plasmid substrates. Among the highlights are excellent coverage of both base excision repair (BER) and nucleotide excision repair (NER), useful assays for identifying and quantifying UV-induced DNA lesions and DNA breakage, gene therapy, environmental mutagenesis and cancer, and gene targeting. |
CUSTOMER REVIEWS (Average Customer Rating: 5.0 based on 1 review)
| DNA Repair Protocols: Eukaryotic Systems by Xingzhi Tan (USA) 5 Stars April 30, 2000 Personally I think "DNA Repair Protocol: Eukaryotic Systems" is a great academic book based on my over ten years of research experiences in Genetic Toxicology. This book provides detailed, step-by-step instructions for studying manifold aspects of the eukaryotic responses to genotoxic damage, including a lot of useful tips in handling all kinds of DNA repair experiments. Compared with Friedberg's textbook "DNA Repair and Mutagenesis", which comprehensively covers all fundamental knowledge about DNA damage, mutagenesis and DNA repair, this book focused on detailed experimental protocols and new techniques, plus a wonderful and concise introduction and explanation of each methods. In my opinion, this book refreshments my background knowledge, gives me an overview of recent progress in new methods and techniques, and ignites some new ideas to pursue further studies in this active field. Taken together, I think this is an essential handbook for professors and scientists in DNA damage and repair field and other related fields.
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Many of the cells in our body undergo tightly regulated replication to enable growth to occur and to ensure that damaged or worn out tissues are replaced. Regulation is mediated via many different mechanisms. It is when these mechanisms fail, and regulation is lost, that cancer can result. Recent advances in molecular cell biology have greatly expanded our understanding of the processes and mechanisms which underpin the regulation of cell replication, and what is happening at the molecular...
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| DNA Repair And Mutagenesis by Errol C. Friedberg (Author), Graham C. Walker (Author), Wolfram Siede (Author), Richard D. Wood (Author), Roger A. Schultz (Author), Tom Ellenberger (Author)
Featuring more than 10,000 references and a text lavishly complemented by over 700 illustrations, "DNA Repair and Mutagenesis, Second Edition" is a timely update to the original edition published in 1995. This work: features three new authors, including an expert in the field of structural biology, ensures a comprehensive review of the most current research in diverse subject areas; presents timely updates to the only comprehensive textbook in the field of DNA repair; offers contributions by...
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