Product Description
Monoclonal Antibodies: Methods and Protocols examines a collection of state-of-the-art methods that employ monoclonal antibodies in a clinical setting with opening chapters focusing on the gold standard method for generating mouse monoclonal antibodies through hybridoma technology, future methods for engineering recombinant and humanized antibodies, methods for engineering soluble Fc fusion protein, and the use of antibodies and flow cytometry in the quantification of cell signaling proteins. Specific chapters describe how antibodies are used for the diagnosis and classification of hematologic diseases. Subsequent chapters examine the advantages and most recent advances of using bead-based immunoassays, including the ability of bead-based technology to multiplex and analyze several analytes simultaneously, and the use of beads in detecting fusion proteins resulting from chromosomal translocations. Concluding chapters provide additional examples of methodologies that employ monoclonal antibodies. Monoclonal Antibodies: Methods and Protocols provides descriptions of methods that cover a wide spectrum of applications in the field of monoclonal antibodies. This field will continue to expand and provide new and innovative techniques, not only in the laboratory, but also as a basis that complements targeted therapy.

SIMILAR PRODUCTS

	Making and Using Antibodies: A Practical Handbook by Gary C. Howard (Editor), Matthew R. Kaser (Editor) Antibodies are an indispensable tool in the study of biology and medicine. Making and Using Antibodies: A Practical Handbook presents techniques in a single, comprehensive source for the production and use of antibodies. It enables researchers to immediately access lab-tested, proven protocols. Written and edited by an elite team of scientists, who have developed and refined many of the methods, this book covers- Commercially available adjuvants designed for the production of...
	Antibody Engineering: Methods and Protocols (Methods in Molecular Biology) by Benny K. C. Lo (Editor) Univ. of Cambridge, UK. Presents cutting-edge techniques for the generation and optimization of recombinant antibodies for offers protocols for affinity maturation and reducing immunogenicity of antibodies. Discusses the novel applications of antigen-binding affinity and specificity. DNLM: Antibodies--therapeutic use--Laboratory Manuals.
	Monoclonal Antibodies in Biotechnology: Theoretical and Practical Aspects (Cambridge Studies in Biotechnology) by Kenneth C. McCullough (Author), Raymond E. Spier (Author) This volume provides a complete description of the principles, methodologies and applications of monoclonal antibodies, one of the most exciting developments to occur in biotechnology in recent years, and a powerful technology for modern industry and science. The immune system and the role of the antibody are described and full details are given on how the hybridomas are formed, isolated, and maintained in culture such that the required antibody can be produced to a high degree of purity. The...
	Antibodies: A Laboratory Manual by Ed Harlow (Author), David Lane (Author) Introduction to immunochemistry for molecular biologists and other nonspecialists. Spiral.
	Kuby Immunology (Kindt, Kuby Immunology) by Thomas J. Kindt (Author), Barbara A. Osborne (Author), Richard A. Goldsby (Author) The only textbook written for undergraduates by teachers of the course, this bestseller presents the most current concepts in an experimental context, conveying the excitement of scientific discovery, and highlighting important advances while providing unsurpassed pedagogical support for the first-time learner. The new edition is thoroughly updated, including most notably the new chapter on innate immunity.