Mechanisms of Sepsis-Induced Organ Dysfunction and Recovery (Update in Intensive Care and Emergency Medicine) | Hardcover

This second, revised edition of Applied Physiology in Intensive Care Medicine aims to help overcome the fundamental unevenness in clinicians’ understanding of applied physiology, which can lead to suboptimal treatment decisions. It is divided into three sections. The first comprises a series of "physiological notes" that concisely and clearly capture the essence of the physiological perspectives underpinning our understanding of disease and response to therapy. The second section contains...

Infections and their complications are a very important clinical area in the intensive care unit setting. Community-acquired infections and nosocomial infections both contribute to the high level of disease acquisition common among critically ill patients. The accurate diagnosis of nosocomial infections and the provision of appropriate therapies, including antimicrobial therapy effective against the identified agents of infection, have been shown to be important determinants of patient...

Sepsis is a serious medical condition, resulting from the immune response to a severe infection. Septicaemia is sepsis of the bloodstream caused by bactemeria, which is the presence of bacteria in the bloodstream. The term septecaemia is also used to refer to sepsis in general. In the US, sepsis is the leading cause of death in non-coronary ICU patients, and the tenth most common form of death overall. Sepsis is common and also more dangerous in the elderly, immunocompromised, and critically...

THE account of the use of mechanical ventilation in critically ill patients

A Doody's Core Title!

4 STAR DOODY'S REVIEW!
"This second edition continues the role established by its predecessor as the leading work in the field. Mechanical ventilation, as a defining event of critical care, has seen an explosion of physiologic and outcomes research in the past decade. Our thinking about management of ARDS, ventilator-induced lung injury, patient-ventilator interaction,...

Hemodynamic monitoring is one of the major diagnostic tools available in the acute care setting to diagnose cardiovascular insufficiency and monitor changes over time in response to interventions. However, the rationale and efficacy of hemodynamic monitoring to affect outcome has come into question. We now have increasing evidence that outcome from critical illness can be improved by focused resuscitation based on existing hemodynamic monitoring, whereas non-specific aggressive resuscitation...