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| View Larger Image | Biodegradable in Situ Microparticles for Sustained Protein Delivery: Stability of a Model Protein during Incorporation and Release from Biodegradable in Situ Forming Drug Delivery Systems | Paperbackby Martin K¿¿rber (Author)
| List Price: | $117.03 | | | Available: | Usually ships in 24 hours |
| | Binding: | Paperback | | Publisher: | VDM Verlag | | Page Count: | 334 Pages | | Publication Date: | August 21, 2008 |
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EDITORIAL REVIEWS |
Product Description
The objective of this work was to evaluate the suitability of in situ forming biodegradable microparticles for the controlled delivery of proteins. Particular goals were: a) to evaluate the flexibility of the release patterns of in situ implant and in situ microparticle formulations using hen egg white lysozyme as model protein; b) to characterize, if and how the integrity of the model protein is affected by formulation ingredients, the manufacturing process, storage of the ISM and the release from the formulations; c) to optimize protein delivery from in situ forming implant and microparticle systems, with regard to shape and completeness of the release; d) to find / validate reliable methods allowing to extract and thus to characterize the model protein in biodegradable in situ formulations. |
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