| View Larger Image | Fabrication of layer-by-layer deposited multilayer films containing DNA and gold nanoparticle for norepinephrine biosensor [An article from: Analytica Chimica Acta] | Digitalby L.P. Lu (Author), S.Q. Wang (Author), X.Q. Lin (Author)
| List Price: | $8.95 | | | Available: | Available for download now |
| | Binding: | Digital | | Publisher: | Elsevier | | Publication Date: | August 16, 2004 |
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Product Description
This digital document is a journal article from Analytica Chimica Acta, published by Elsevier in 2004. The article is delivered in HTML format and is available in your Amazon.com Media Library immediately after purchase. You can view it with any web browser.Description: The present work describes the preparation and characterization of an electrodeposited DNA membrane doped with gold nanoparticles for the design of biosensors. The gold nanoparticles were deposited on the surface of DNA layer to build a hybrid device of nanoscale electrode array. The gold nanoparticles-doped DNA composite electrode was characterized by atomic force microscopy, scanning electron microscope, and electrochemistry involving electrochemical impedance spectroscopy. This electrode was successfully used for selective determination of norepinephrine (NE) in the presence of ascorbic acid (AA). The reversibility of the electrode oxidation reaction of NE is significantly improved in result of 200mV negative shift of the voltammetric peak potential on the electrode, and a large increase in the peak current. A detection limit of 5nM NE is obtained by using DPV in static solutions. The co-existence of a large excess of AA does not interfere with the detection. This electrode shows excellent sensitivity, good selectivity and antifouling properties. |
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