| View Larger Image | Evaluation of the effect of governmental control of human exposure to two phthalates in Japan using a urinary biomarker approach [An article from: International ... Journal of Hygiene and Environmental Health] | Digitalby H. Itoh (Author), K. Yoshida (Author), S. Masunaga (Author)
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| | Binding: | Digital | | Publisher: | Elsevier |
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EDITORIAL REVIEWS | Product Description This digital document is a journal article from International Journal of Hygiene and Environmental Health, published by Elsevier in . The article is delivered in HTML format and is available in your Amazon.com Media Library immediately after purchase. You can view it with any web browser.Description: In Japan, the use of certain phthalates has been regulated. We analyzed the effectiveness of these measures using an analytical biomarker approach. We measured two phthalate metabolites, mono-n-butyl phthalate (MBP) and mono-2-ethylhexyl phthalate (MEHP) in urine samples from 36 participants using enzymatic deconjugation, offline solid phase extraction, and HPLC-ESI-MS/MS. From the levels measured and individual values of creatinine excretion rate the daily intake was determined and compared to each corresponding tolerable daily intake (TDI). The levels of urinary MBP and MEHP were |
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