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Increased levels of polychlorobiphenyls in Italian women with endometriosis [An article from: Chemosphere]
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Increased levels of polychlorobiphenyls in Italian women with endometriosis [An article from: Chemosphere] | Digital

by M.G. Porpora (Author), A.M. Ingelido (Author), A.d. Domenico (Author), Ferro (Author)

List Price: $10.95  
Available:  Available for download now

Binding:  Digital
Publisher:  Elsevier
Page Count:  6 Pages
Publication Date:  May 01, 2006


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Product Description
This digital document is a journal article from Chemosphere, published by Elsevier in 2006. The article is delivered in HTML format and is available in your Amazon.com Media Library immediately after purchase. You can view it with any web browser.Description: Endometriosis has been hypothesised to be linked to persistent and toxic organochlorinated chemicals. Dioxins and dioxin-like compounds have in particular been associated with the disease, mainly on the basis of experimental studies. Data in women are conflicting. A case-control study on 80 Italian nulliparous women of reproductive age was carried out to assess whether there is a correlation between the presence of endometriosis and blood levels of polychlorobiphenyls (PCBs), a family of ubiquitary environmental pollutants which comprises congeners with dioxin-like activity. Higher levels of PCBs were found in women with endometriosis. A mean cumulative value of 410ngg^-^1, lipid base, was found in cases versus the value of 250ngg^-^1 observed in the control group (odds ratio for upper tertile 4.0, CI 95% 1.3-13; p=0.0003). PCB increase involved both dioxin-like (PCBs 105, 118, 156, and 167) and non-dioxin-like congeners (PCBs 101, 138, 153, 170, 180).
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