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New directions in tissue repair and regeneration
May 04, 2004PHILOSOPHICAL TRANSACTIONS B MAY ISSUE
New directions in tissue repair and regeneration
- a discussion meeting issue organised and edited by Jeremy Brockes and Paul Martin
This volume will consider new information on regeneration and wound healing as biological mechanisms in a variety of species ranging from the planarian worm which can be cut into 100 pieces, each of which will regenerate into a new individual in a week, to the deer antler which, under sex hormone control, sheds and then regenerates complex organ pattern annually. The fields of repair and regeneration are now integrating with elements of stem cell biology and tissue engineering in ways that offer real opportunities for clinical applications that will allow us to replace tissues damaged by trauma or disease in the not-too-distant future.
The 13 papers in this issue are available online: http://www.journals.royalsoc.ac.uk/openurl.asp?genre=issue&eissn=1471-2970&volume=359&issue=1445
Table of Contents
Introduction 743
J. P. Brockes & P. Martin
Cellular and molecular mechanisms of regeneration in Xenopus 745
J. M. W. Slack, C. W. Beck, C. Gargioli & B. Christen
Fibroblast growth factors in epithelial repair and cytoprotection 753
S. Braun, U. auf dem Keller, H. Steiling & S. Werner
Regeneration and the need for simpler model organisms 759
A. S'ˇnchez Alvarado
A critical role for thrombin in vertebrate lens regeneration 765
Y. Imokawa, A. Simon & J. P. Brockes
Wound healing and inflammation: embryos reveal the way to perfect repair 777
M. J. Redd, L. Cooper, W. Wood, B. Stramer & P. Martin
The scarless heart and the MRL mouse 785
E. Heber-Katz, J. Leferovich, K. Bedelbaeva, D. Gourevitch & L. Clark
Genetic approaches to disease and regeneration 795
M. T. Keating
Retinoic acid in alveolar development, maintenance and regeneration 799
M. Maden & M. Hind
Exploring the mechanisms regulating regeneration of deer antlers 809
J. Price & S. Allen
Stem cells: cross-talk and developmental programs 823
J. Imitola, K. I. Park, Y. D. Teng, S. Nisim, M. Lachyankar, J. Ourednik, F.-J. Mueller, R. Yiou, A. Atala, R. L. Sidman, M. Tuszynski, S. J. Khoury & E. Y. Snyder
Scar-free healing: from embryonic mechanisms to adult therapeutic intervention 839
M. W. J. Ferguson & S. O'Kane
Stem cell biology and neurodegenerative disease 851
R. D. McKay
Royal Society, The
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