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University of Kent bioscientists receive grant to research novel cancer treatment
March 16, 2004Dr Phil Blower and Dr Dan Lloyd from the Department of Biosciences at the University of Kent - together with Dr Paul Marsden at the St Thomas' Hospital Clinical PET Centre in London - have been awarded £347,906 from the Engineering and Physical Sciences Research Council and the Medical Research Council for a project entitled Radiocopper complexes for imaging and treatment of hypoxic tissues.
Dan Lloyd explains that 'Hypoxia is a shortage of oxygen in tissues and occurs in many diseases such as stroke, heart disease and cancer. It is one of the main causes of cancer treatment failure, since hypoxic tumours are often resistant to conventional radiotherapy and chemotherapy.
This multi-disciplinary project will involve the synthesis and evaluation of molecules, coupled to radioactive isotopes that specifically target hypoxic tissue. It is hoped that the work will result in the development of both imaging procedures to locate hypoxic tissues within the body, and therapeutic strategies for the treatment of resistant hypoxic tumours.'
Phil Blower adds, 'The imaging procedures will use PET (positron emission tomography), a radioisotope imaging technique especially useful in imaging cancer and brain function. The UK lags behind many other countries in establishing PET centres and has only a small number of them. The PET centre at St Thomas' Hospital was set up more than a decade ago and was the UK's first PET centre offering a routine service to patients, but more centres are now needed to bring these new technologies to cancer patients across the country.'
Dr Dan Lloyd and Dr Phil Blower are members of the Cancer Research Group at the University of Kent that was established to reflect the growing amount of research activities within the Department of Biosciences seeking new approaches to the diagnosis and treatment of cancer.
Kent, University of
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