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Inflammatory bowel disease is a risk factor for thrombosis
March 09, 2004People with inflammatory bowel disease (IBD) are more than three times as likely to develop blood clots in their veins (venous thromboembolism), finds new research in Gut.
Thromboembolism is a serious and potentially life threatening event. For many years, patients with IBD were thought to be at increased risk, but the evidence has been inconsistent.
Furthermore, it is not known if this risk is specific for IBD or if it is shared by other chronic inflammatory diseases or bowel disorders, such as rheumatoid arthritis or coeliac disease.
Researchers surveyed 618 patients with IBD, 243 with rheumatoid arthritis, 207 with coeliac disease. All three patient groups were compared with matched control patients.
A total of 38 IBD patients (6.2%) suffered thromboembolism. This was significantly higher than the matched control group with only 10 cases reported (1.6%). The risk of thromboembolism was no higher in patients with rheumatoid arthritis or coeliac disease compared with controls.
IBD is a risk factor for thromboembolism, say the authors. It seems that thromboembolism is a specific feature of IBD as neither rheumatoid arthritis, nor coeliac disease had an increased risk. However, there appears to be no obvious explanation for these findings.
British Medical Journal (BMJ)
Arthritis Current Events and Arthritis News RSSHodgkin lymphoma -- new characteristics discovered
Researchers are still discovering new characteristics of Hodgkin lymphoma, a common form of cancer of the lymphatic system. The malignant cells are derived from white blood cells (B cells), but have lost a considerable part of the B cell-specific gene expression pattern.
Incorporating Education in Exercise Programs Increases Benefits for Arthritis Patients, MU Researchers Find
Arthritis is the nation's most common cause of disability. The number of adults with doctor-diagnosed arthritis is projected to increase to 67 million by 2030, and a large proportion of U.S. adults will limit their activity as a result.
Discovery of natural compounds that could slow blood vessel growth
Using computer models and live cell experiments, biomedical engineers at the Johns Hopkins University School of Medicine have discovered more than 100 human protein fragments that can slow or stop the growth of cells that make up new blood vessels.
UCR researchers propose minocycline as a promising drug for patients with Fragile X syndrome
A UC Riverside-led team of biomedical scientists has found that a readily available drug called minocycline, used widely to treat acne and skin infections, can be used to treat Fragile X syndrome, the most common inherited cause of mental impairment and the most common cause of autism.
New study proves that pain is not a symptom of arthritis, pain causes arthritis
Pain is more than a symptom of osteoarthritis, it is an inherent and damaging part of the disease itself, according to a study published today in journal Arthritis and Rheumatism.
Supplements no better than placebo in slowing cartilage loss in knees of osteoarthritis patients
In a two-year multicenter study led by University of Utah doctors, the dietary supplements glucosamine and chondroitin sulfate performed no better than placebo in slowing the rate of cartilage loss in the knees of osteoarthritis patients.
Occupational therapy gets people with osteoarthritis moving
Physical activity is the cornerstone of any healthy lifestyle - and especially for people with osteoarthritis as exercise helps maintain good joint health, manage their symptoms, and prevent functional decline. Osteoarthritis, however, often makes physical activity, such as exercise, and even performing daily activities, a challenge.
Working environment is 1 cause of rheumatoid arthritis
It has long been known that environmental factors play a part in the development of rheumatoid arthritis; smoking and drinking alcohol, along with heredity, are particularly instrumental in increasing the risk of the disease.
Sinusitis patients have pain similar to the elderly and people with arthritis
A new analysis led by researchers at Georgetown University Medical Center suggests many patients with sinusitis have aches and pains similar in severity to people in their 80s and those with arthritis or depression.
The prevalence of hepatitis B virus infection in inflammatory bowel disease patients
Patients with IBD have high risk of infection by hepatitis viruses B or C because during the course of their disease, they need blood transfusions, and sometimes surgical and endoscopic procedures for diagnosis and treatment.
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