 |
|
Enrollment in cancer trials not linked to better health outcomes (p 263)
January 21, 2004The widely held view that people with cancer who participate in clinical trials have better treatment outcomes is disputed by US authors of a study in this week's issue of THE LANCET.
Less than 5% of adults with cancer are enrolled into clinical trials. Steven Joffe from the Dana-Farber Cancer Institute, Boston, USA, and colleagues reviewed 26 previously published studies that compared the health outcomes of cancer patients enrolled or not enrolled in clinical trials.
Although 14 of the studies suggested a beneficial health outcome for trial participants, most studies did not effectively control for bias. For example, only nine studies required the same entry criteria for participating and non-participating patients, and only three of these found that trial participants had better outcomes than non-participants.
Steven Joffe comments: "Until more convincing evidence for a trial effect is available, recruitment messages to patients considering trials should focus on their contribution to advances in treatment. We believe that patients, professionals, and third-party payers can recognise the crucial function of clinical trials in advancing treatment, and that de-emphasising direct benefits to patients need not compromise accrual or coverage. We remain optimistic that strong support for trials can flourish on the basis of their unquestioned role in improving options and outcomes for patients with cancer."
Lancet
Cancer Current Events and Cancer News RSSGenetic breakdown in Fanconi anemia may have link to HPV-associated cancer
A genetic malfunction that causes DNA instability in people with the blood disorder Fanconi anemia may put them at high risk for squamous cell carcinomas linked to human papillomavirus (HPV), according to a study posted online ahead of print by Oncogene.
International study supports new standard of treatment for women with advanced ovarian cancer
Results of a phase III, international randomized clinical trial demonstrate a new standard of care for treating advanced ovarian cancer that significantly reduces side-effects and post-operative deaths compared to the previously established treatment course.
Researchers identify cell group key to Lyme disease arthritis
A research team led by the La Jolla Institute for Allergy & Immunology and Albany Medical College has illuminated the important role of natural killer (NK) T cells in Lyme disease, demonstrating that the once little understood white blood cells are central to clearing the bacterial infection and reducing the intensity and duration of arthritis associated with Lyme disease.
Researchers Discover New Enzyme in Cancer Growth
While studying the mechanics of blood clots, researchers at the University of Oklahoma Health Sciences Center discovered a new enzyme that not only affects the blood, but seems to play a primary role in how cancer tumors expand and spread throughout the body.
Angled gantry technique reduced breast radiation exposure by 50 percent
A novel angled gantry approach to coronary CT angiography reduced radiation exposure to the breast by more than 50%, according to Thomas Jefferson University researchers.
HER2 levels may aid in treatment selection for metastatic breast cancer
Findings published in the December 1, 2008, issue of Clinical Cancer Research, a journal of the American Association for Cancer Research, show lapatinib benefits women with HER2-positive breast cancer, while women with HER2-negative breast cancer or those who express EGRF alone derive no incremental benefit.
Drop in cancer deaths tied primarily to gains in behavior and screening
Improvements in behavior and screening have contributed greatly to the 13 percent decline in cancer mortality since 1990, with better cancer treatments playing a supporting role, according to new research from David Cutler of Harvard University.
Plants display 'molecular amnesia'
Plant researchers from McGill University and the University of California, Berkeley, have announced a major breakthrough in a developmental process called epigenetics. They have demonstrated for the first time the reversal of what is called epigenetic silencing in plants.
New breast imaging technology targets hard-to-detect cancers
Breast-specific gamma imaging (BSGI) is effective in the detection of cancers not found on mammograms or by clinical exam, according to a study presented today at the annual meeting of the Radiological Society of North America (RSNA).
Dancing atoms now understood
In developing a model to explain the motion of atoms in a magnetic field, scientists have overcome a decades-old obstacle to understanding a key component of magnetic resonance.
More Cancer Current Events and Cancer News Articles
 | Beating Cancer with Nutrition by Patrick Quillin Beating Cancer with Nutrition · Sugar feeds Cancer: diet and supplements can starve tumors · Nutrition makes chemo and radiation more toxic to the tumor while protecting the patient · Nutrition changes underlying causes of cancer, improving outcome for cancer patients regardless of other therapies. Why Beating Cancer with Nutrition is unique: The book was developed after working... |
 | Cancer on Five Dollars a Day (chemo not included): How Humor Got Me Through the Toughest Journey of My Life by Robert Schimmel In the spring of 2000, Robert Schimmel was riding high. He'd won the Stand-Up of the Year Award, his HBO special was a huge hit, and his sitcom had been picked up. And then it all came crashing down. Diagnosed with Stage III non-Hodgkin's lymphoma, he was told he would have to undergo chemotherapy immediately. The sitcom was dumped and the fire of his white-hot career started to go out. But... |
 | Tropic of Cancer by Henry Miller Now hailed as an American classic, Tropic of Cancer, Henry Miller's masterpiece, was banned as obscene in this country for 27 years after its publication in Paris in 1934. Only a historic court ruling that changed American cesorship standards permitted the publication of this first volume of Miller's famed mixture of memoir and fiction, which chronicles with unapologetic gusto the bawdy... |
 | Cancer-Free: Your Guide to Gentle, Non-toxic Healing (Second Edition) by Bill Henderson "If you love your stricken one, this is your Bible." said Denzel Koh of Brisbane, Australia after he healed his daughter's cancer using the information in a previous edition of this book. A cancer diagnosis always causes fear. All of us have seen relatives and friends destroyed by conventional cancer treatment. Now, thanks to books like this one and the Internet, you can quickly... |
 | How to Fight Cancer & Win by William L. Fischer Maximize your chance of recovery from cancer - and learn how to prevent it - with this down-to-earth, practical guide that has saved and improved lives since its first publishing in 1992. This accessible book presents scientific guidelines and documented facts for the successful treatment and prevention of cancer and other health problems, and is a must-read for everyone, from those looking for... |
 | Crazy Sexy Cancer Tips (Crazy Sexy) by Kris Carr An advice-from-the-trenches cancer survival guidebook for young women with cancer. Actress and photographer Kris Carr thought she had a hangover, but a Jivamukti yoga class didn't provide its usual kick-ass cure. A visit to her doctor confirmed her "liver looked like Swiss cheese," covered with cancerous tumors. She entered trench warfare (wearing cowboy boots into the MRI machine,... |
 | Dr. Patrick Walsh's Guide to Surviving Prostate Cancer, Second Edition by Patrick C. Walsh, Janet Farrar Worthington EVERY MAN NEEDS THIS BOOK! Each year, more than 200,00 American men are diagnosed with prostate cancer. The good news is that more men are being cured of this disease than ever before. Now in a revised second edition, this lifesaving guide by Dr. Patrick Walsh and ard-winning science writer Janet Farrar Worthington offers a message of hope to every man facing this illness. Prostate cancer is... |
 | Foods to Fight Cancer: Essential foods to help prevent cancer by Richard Beliveau Detailing the key foods that have been medically shown to be beneficial in both preventing and fighting cancer, this is the must-have resource for anyone looking to get healthy and stay that way. AUTHOR BIO: Richard Béliveau, PhD, a leading authority in cancer research, holds the Chair in the Prevention and Treatment of Cancer at the Université du Quebec à Montréal, where he is a professor... |
 | Cancer - Step Outside the Box by Ty M. Bollinger If you're concerned about the "C" word, then the first thing you need to know is that cancer does NOT have to be a death sentence! There is hope! There are many potent and well-proven alternative strategies for preventing, treating, and even curing cancer... without surgery, chemotherapy, or radiation (i.e. the "Big 3"). Inside this book, you will find a wealth of information that your... |
 | Cancer: 50 Essential Things to Do: Revised and Updated Edition by Greg Anderson, O. Carl Simonton (Foreword) This definitive guide, revised and updated with over 25% new material, empowers cancer patients and their loved ones to move beyond their disease. Greg Anderson, a cancer survivor, has designed this book for the recently diagnosed, those with recurring symptoms, and those who are well but have a lingering fear that the disease may strike again. Informative and inspiring, Cancer: 50 Essential... |
| © 2008 BrightSurf.com |