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Patients with throat cancer should have endoscopic ultrasound examination
December 18, 2003Research News from British Journal of Surgery
The surgery needed to remove throat tumours is severe and often involves drawing the stomach higher into the chest cavity. Before surgeons embark on this risky procedure they need to believe that the patient has a good chance of benefiting from the operation.
Endoscopic ultrasonography is a fairly new technique, and so far there has been relatively little use of it in the UK. But a study of 150 patients with throat cancer found that using endoscopic ultrasound examinations helped doctors form a more accurate diagnosis of the status of a throat tumour than other techniques such as CT scans and tissue biopsies. The findings are published in the latest edition of the British Journal of Surgery.
"Endoscopic ultrasound should be performed in all patients because it is the most accurate preoperative method of determining surgical respectability and prognosis," says Professor Jean-Pierre Triboulet, who carried out the study with a team of researchers in Lille, France.
The researchers believe that this technique is probably the best way of distinguishing between patients with early cancer who could be treated by surgery alone, and those with advanced cancer for whom non-surgical or neoadjuvant treatment would possibly be a better option.
John Wiley & Sons
Cancer Current Events and Cancer News RSSMetabolic reactions: Less is more in single-celled organisms
A Northwestern University study has found a surprising similarity among four quite different organisms. The simplest organism, a bacterium called H. pylori, uses the same number of biochemical reactions (around 300) as yeast, the largest, most complex organism of the group, when optimizing growth.
Genetic breakdown in Fanconi anemia may have link to HPV-associated cancer
A genetic malfunction that causes DNA instability in people with the blood disorder Fanconi anemia may put them at high risk for squamous cell carcinomas linked to human papillomavirus (HPV), according to a study posted online ahead of print by Oncogene.
International study supports new standard of treatment for women with advanced ovarian cancer
Results of a phase III, international randomized clinical trial demonstrate a new standard of care for treating advanced ovarian cancer that significantly reduces side-effects and post-operative deaths compared to the previously established treatment course.
Researchers identify cell group key to Lyme disease arthritis
A research team led by the La Jolla Institute for Allergy & Immunology and Albany Medical College has illuminated the important role of natural killer (NK) T cells in Lyme disease, demonstrating that the once little understood white blood cells are central to clearing the bacterial infection and reducing the intensity and duration of arthritis associated with Lyme disease.
Researchers Discover New Enzyme in Cancer Growth
While studying the mechanics of blood clots, researchers at the University of Oklahoma Health Sciences Center discovered a new enzyme that not only affects the blood, but seems to play a primary role in how cancer tumors expand and spread throughout the body.
Angled gantry technique reduced breast radiation exposure by 50 percent
A novel angled gantry approach to coronary CT angiography reduced radiation exposure to the breast by more than 50%, according to Thomas Jefferson University researchers.
HER2 levels may aid in treatment selection for metastatic breast cancer
Findings published in the December 1, 2008, issue of Clinical Cancer Research, a journal of the American Association for Cancer Research, show lapatinib benefits women with HER2-positive breast cancer, while women with HER2-negative breast cancer or those who express EGRF alone derive no incremental benefit.
Drop in cancer deaths tied primarily to gains in behavior and screening
Improvements in behavior and screening have contributed greatly to the 13 percent decline in cancer mortality since 1990, with better cancer treatments playing a supporting role, according to new research from David Cutler of Harvard University.
Plants display 'molecular amnesia'
Plant researchers from McGill University and the University of California, Berkeley, have announced a major breakthrough in a developmental process called epigenetics. They have demonstrated for the first time the reversal of what is called epigenetic silencing in plants.
New breast imaging technology targets hard-to-detect cancers
Breast-specific gamma imaging (BSGI) is effective in the detection of cancers not found on mammograms or by clinical exam, according to a study presented today at the annual meeting of the Radiological Society of North America (RSNA).
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