 |
|
Reducing the risks of GM micro-organisms
December 09, 2003Scientists have developed a system to increase the safety of genetically modified (GM) microbes for release into the environment.
Release of GM micro-organisms is a cause of great concern to many, because the microbes could pass on genes for disease or other harmful traits to others. But, a team of researchers from Spain and Germany believes that it is possible to reduce this risk.
"Lethal functions are any kind of molecule, usually proteins, that causes killing of the microbial cells," explains Dr D'az.
In the GM microbe, the lethal functions associated with the GM trait are not active. However, if this trait is transferred to a different microbe, the associated lethal functions become active and the recipient microbe dies (gene containment). Lethal functions can also be activated in the GM microbe upon completion of the biotechnological process by a specific signal from the environment, such as root exudates, temperature, or toxic pollutants (biological containment).
However, microbes can mutate, becoming resistant to the toxic effect of the lethal function. This leads to survival of a small fraction of the GM microbial population, which can multiply and then spread, uncontrolled. Avoiding the spread of potentially harmful traits is vital if GM microbes are to be used for our benefit.
Simply increasing the number of lethal functions helps to overcome this. "It is easier to inactivate one lethal function, than to inactivate two or more," says Dr D'az. However, this only works if the lethal functions (proteins) are different, if the functions act on different targets within the microbial cell, and if the functions are controlled separately. To become resistant to each individual lethal function would require numerous mutations.
Safe GM organisms would be of great benefit in applications where large amounts of microbes are needed, such as degrading pollutants on contaminated land, or for the development of live vaccines to prevent disease.
Society for General Microbiology
Science Research Departments
Earth Science
Alternative Energy | Anthropology and Archaeology | Earthquakes and Volcanoes | Environment and Nature News | Global Warming | High-Energy and Particle Physics | Ozone Hole | Scientists Slow Light | Tsunami
Space Science
Astronomy and Space News | Black Holes | Chandra X-Ray Observatory | Extrasolar Planets | Hubble Telescope | International Space Station | Jupiter Galileo Mission | Jupiter Cassini Mission Flyby | Mars Exploration | Mars Odyssey 2001 | Mars Global Surveyor | Mars Polar Lander | Mars Climate Orbiter | Mars Pathfinder | Meteors and Asteroids | Mir Space Station | NEAR Asteroid Probe Mission | Pluto Planet Debate | Search for Extraterrestrial Life | Space Shuttle Program | Space Shuttle Mission: STS-102 | Space Weather
Life Science
Animal News | Biotechnology and Genetics | Brain Research | Human Cloning | Dinosaur and Fossil Discoveries | Endangered Species | Gene Therapy | Genetically Modified Food | Stem Cell Research | Whales and Whaling
 |
Scientific Explorer's Mind Blowing Science Kit for Young Scientists by Scientific Explorer Mind blowing experiments to delight and educate young scientists! Erupt a color changing volcano. Mix up magic ooze with a mind of its own. Play with sand that never gets wet. Mix safe chemicals and watch colors change before your eyes. You'll amaze yourself and your friends as you explore the science behind these truly remarkable reactions. |
 |
The Everything Kids' Science Experiments Book: Boil Ice, Float Water, Measure Gravity-Challenge the World Around You! (Everything Kids Series) by Tom Robinson (Author) Science has never been so easy - or so much fun! With The Everything Kids' Science Experiments Book, all you need to do is gather a few household items and you can recreate dozens of mind-blowing, kid-tested science experiments. High school science teach Tom Robinson shows you how to expand your scientific horizons - from biology to chemistry to physics to outer space. You'll discover answers to questions like: Get ready to enter the laboratory and learn how to conduct cool experiments, understand scientific terms... |
 |
Scientific Explorer's Disgusting Science - A Kit for Studying the Science of Revolting Things by Scientific Explorer Grow your own friendly germs and fuzzy molds. Mix up a batch of coagulating fake blood. Even make a stinky intestine. learn the science behind unmentionable bodily functions while doing some truly NASTY Experiments. Ages 8+ |
 |
The Science Book: Everything You Need to Know About the World and How It Works (National Geographic) by National Geographic (Author), Marshall Brain (Foreword) A delight for the casual reader, yet so complete and wide-ranging that science buffs and students will welcome it, The Science Book encapsulates centuries of scientific thought in one richly illustrated volume. Natural phenomena, revolutionary inventions, and the most up-to-date investigations are explained in detailed text, and 2,000 vivid illustrations—including 3-D graphics and pictograms—make the information even more accessible and amazing to discover. The Science Book offers both a general overview of topics for the browsing reader and more specific information for those seeking deeper insight into a particular subject. Six major sections, ranging from the universe and planet Earth to biology, chemistry, physics, and mathematics, encompass everything from microscopic life... |
 |
Scientific Explorer's The Magic Science Wizard's Kit by Scientific Explorer Cast real smoke from your fingertips, make a wizard wand, and whip up color-changing potions in your test tube laboratory. Also included are laminated cards with wizard facts, an instruction booklet with 11 activities, lab equipment, and mysterious wizard powders that will mix together to mystify you! |
 |
Snap Circuits Jr. SC-100 by Elenco Electronics Inc Dr. Toy 100 Best Children's Products Winner We venture even Edison would be intrigued. Prepare to engineer 101 exciting, useful electronic gadgets & play lively electronic games with Snap Circuits Jr! This kit features a great collection of materials! The colorful and easy-to-follow format of the instruction manual makes circuit assembly stress-free and fun. All projects are simple to build and understand. Perfect for the novice engineer. All parts are mounted on plastic modules and snap together with ease. Leave the tools in the garage; everything you need for your electronics learning adventure is included. With Snap Circuits Jr. your understanding of electronics is a SNAP! 101 High Interest Projects Just a few: Flying Saucer, Music Alarm Combo, Pencil Alarm, Space... |
 |
Science: The Definitive Visual Guide by Adam Hart-Davis (Author) This remarkable reference book tells the story of science from earliest times to the present day, taking in everything from ancient Greek geometry to quantum physics, and the wedge to the worldwide web. Exploring science in a thematic, highly approachable manner, each spread takes as its theme a specific event, discovery, invention, experiment, theory, or individual and explains why this subject was so significant in the development of scientific thought and what its impact on history has been. In addition to providing a broad-ranging and comprehensive history of science, the book also explains how science works, employing DK's trademark clarity and visual ingenuity to render tricky scientific subjects easily comprehensible. Science is structured chronologically with five... |
 |
Magic School Bus Journey into the Human Body Science Kit by Young Scientist Club The Magic School Bus and Ms. Frizzle take Young Scientists on a wild ride into the human body with these breathtaking experiments. Young Scientists bend bones, make joints, map taste buds, expand lungs, build a stethoscope, measure lung capacities and heart rates, perform the iodine starch test, spin glitter, simulate synovial fluid, create a human body poster, and much, much more! This exciting kit includes a life-size poster with eight sheets of body part stickers. So put on your seat belts, students, and get ready to discover The Human Body! |
 |
Scientific Explorer's Spa Science Chemistry Kit by Scientific Explorer Whip your bath into a frothy fizzing sea of color and fragrance. Make colorful, fragrant bath gels, bath fizzers, spa lotion, bath balm, a face mask, and shampoo. Mix colors and fragrances to creat your own product line with secret and exclusive mixtures. Explore the science of gels, fragrance and fizzers. |
 |
The Complete Book of Science, Grades 5-6 by School Specialty Publishing (Author) The Complete Book of Science for grades 5 to 6 teaches children important science skills!
Children complete a variety of exercises that help them develop a number of skills in this 352 page workbook. Including a complete answer key this workbook features a user-friendly format perfect for browsing, research, and review.
Over 4 million in print! The best-selling Complete Book series offers a full complement of instruction, activities, and information about a single topic or subject area. Containing over 30 titles and encompassing preschool to grade 8 this series helps children succeed in every subject area! ... |
| © 2009 BrightSurf.com |