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Type 1 diabetes associated with increased risk of cancer
December 04, 2003Certain forms of cancer occur more often in patients with type 1 diabetes compared with the general population in the corresponding sex and age groups. This has been shown in a new Swedish study from Karolinska Institutet.
The study, which has been published this week, is the first large-scale investigation of the risk of cancer among patients with type 1 (youth onset) diabetes. It included nearly 30,000 patients who had been treated at hospitals between 1965 and 1999. Of these, 355 received a cancer diagnosis, which represents 20 percent more than would be expected in the Swedish population of the corresponding sex and age. Increased risk was shown specifically for cancer of the stomach, cervix, and womb. On the other hand, no increase in risk was apparent regarding cancer of the breast, colon/rectum, or kidney. Nor was there any rise in the risk of developing cancer of the pancreas, which was observed in patients with type 2 (adult onset) diabetes.
Diabetes is actually two diseases, with different causes and mechanisms. The most common type is adult onset diabetes (type 2), which usually appears in mature adults. The other variety is type 1, with its onset occurring in childhood or adolescence. Thus far there have been very few individuals with type 1 diabetes among those reaching cancer age, since treatments available in the first two thirds of the 20th century were unable to prevent the complications leading to early death. However, with today's careful monitoring and treatment, the length of patients' lives has increased dramatically.
Vetenskapsrådet (The Swedish Research Council)
Vetenskapsrådet (The Swedish Research Council)
Diabetes Current Events and Diabetes News RSSPediatric obesity may alter thyroid function and structure
In addition to its strong associations with hypertension, cardiovascular disease, and diabetes, pediatric obesity may induce alterations in thyroid function and structure, according to a new study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM).
New study identifies link between Alzheimer's disease biomarkers in healthy adults
The Netherlands -- A study published in the November issue of the Journal of Alzheimer's Disease provides an insight into normal, physiological levels and association between proteins involved in development of Alzheimer's disease.
Cardiovascular disease causing increasing inequity between rich and poor
A new paper released today by The George Institute for International Health is warning a cardiovascular disease based epidemic is gaining pace among many low- and middle-income countries (LMIC), exemplified at its worst in the world's largest populated countries - China and India.
Antibiotics: Single largest class of drugs causing liver injury
Antibiotics are the single largest class of agents that cause idiosyncratic drug-induced liver injury (DILI), reports a new study in Gastroenterology, an official journal of the American Gastroenterological Association (AGA) Institute.
Persistent pollutant may promote obesity
Tributyltin, a ubiquitous pollutant that has a potent effect on gene activity, could be promoting obesity, according to an article in the December issue of BioScience.
Presence of gum disease may help dentists and physicians identify risk for cardiovascular disease
Individuals reporting a history of periodontal disease were more likely to have increased levels of inflammation, a risk factor for heart disease, compared to those who reported no history of periodontal disease.
Drink brewed tea to avoid tooth erosion
Today, the average size soft drink is 20 ounces and contains 17 teaspoons of sugar. More startling is that some citric acids found in fruit drinks are more erosive than hydrochloric or sulfuric acid-which is also known as battery acid.
Understanding how oxidative stress impairs endothelial progenitor cell function
Although its been over a decade since endothelial progenitor cells or EPCs, cells that circulate in the blood repairing and replacing the cells that line blood vessels, were identified, the field is still evolving.
Exercise helps overweight children reduce anger expression
Regular exercise seems to reduce anger expression in overweight but otherwise healthy children, researchers said.
Sealing off portion of intestinal lining treats obesity, resolves diabetes in animal model
Lining the upper portion of the small intestine with an impermeable sleeve led to both weight loss and restoration of normal glucose metabolism in an animal model of obesity-induced diabetes.
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