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ESC Congress 2003: Preferred treatment of angina (chest pain)

September 01, 2003

IMPORTANT: This press release accompanies a poster or oral session given at the ESC Congress 2003. Written by the investigator himself/herself, this press release does not necessarily reflect the opinion of the European Society of Cardiology

ESC Congress 2003: We have shown that in European and Mediterranean patients with stable angina and proven coronary artery disease the preferred treatment in the majority of patients is mainly determined by the characteristics of the coronary angiogram (x-ray of the coronary arteries). The preferred therapy in these patients was balloon angioplasty, followed by open heart surgery and medical therapy.




Between September 2001 and March 2002, we included over 5,500 patients with proven narrowing of coronary arteries on the coronary angiogram in 130 hospitals throughout Europe and the Mediterranean (Euro Heart Survey on Coronary Revascularisation). This survey programme provides systematic information on the management of patients with heart disease. The aim was to assess the relation between the patient, clinical and angiographic, characteristics and the choice of therapy in clinical practice. We studied 2.973 patients with stable angina, defined as a recurring pain or discomfort in the chest when some of the heart muscle does not receive enough blood.

Based on an extensive list of patient characteristics we made a model to evaluate the predictors of the treatment. First we compared medical therapy with invasive (open heart surgery and balloon angioplasty) therapy, and second, we compared open heart surgery with balloon angioplasty. Balloon angioplasty involves insertion of a catheter with a tiny balloon at the end into a coronary artery. The balloon is inflated briefly to open the vessel in places where the artery is narrowed.

We observed that the number of diseased coronary arteries and the complexity of the narrowing of coronary arteries are the most significant determinants of the therapeutic choice. If a patient has single vessel disease or previously had open heart surgery the therapy is twice to four times as often medical than invasive. Patients with less complicated narrowing are more likely to receive invasive therapy.

In the invasive treatment group, the therapeutic choice was significantly more often balloon angioplasty than open heart surgery. The predictors of this treatment were single vessel disease, prior open heart surgery and no accompanying heart valve disease. In patients with a prior heart attack or high blood pressure no treatment was significantly preferred.

This research gives insight in the treatment of patients with stable coronary artery disease. Whether the determinants of the choice of therapy influence the eventual health of heart patients needs to be followed up.

Dr Marjo Hordijk-Trion
Thoraxcentre Rotterdam, Erasmus
The Netherlands

European Society of Cardiology (ESC)



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