Science Current Events | Science News | Brightsurf.com
 

Demand for radiotherapy will rise substantially over next 10 years

April 19, 2016

The demand for radiotherapy across all European countries will increase by an average of 16% between 2012 and 2025, with the highest expected increase being for prostate cancer cases (24%), according to a new study published in Radiotherapy and Oncology [1].

These projections come from a new study by HERO, the Health Economics in Radiation Oncology project of the European Society for Radiotherapy and Oncology. The results will also be presented at the ESTRO 35 conference [2], to be held in Turin, Italy, from Friday 29 April - Tuesday 3 May 2016.

"Because radiotherapy involves significant outlay in equipment costs as well as in staff, long-term planning is necessary in order to achieve the required results. We, therefore, decided to try to forecast the radiotherapy needs of new cancer patients in the short to medium term in order to gain sufficient time for the purchase of appropriate machinery and the personnel training that will be required to meet this need," said Professor Yolande Lievens, from the Radiation Oncology Department, Ghent University Hospital, Ghent, Belgium, who is a co-author of the paper and president elect of ESTRO.

The research group, made up of senior radiation oncologists and epidemiologists from Belgium, Denmark, Spain, France and Australia, analysed European cancer incidence for the year 2013 by country and by tumour site, using data from the International Agency for Research on Cancer (IARC) GLOBOCAN project on worldwide cancer incidence and mortality.

Using statistical modelling, the researchers applied the 2012 country, sex and site incidence rates to the population forecast for 2025 in order to obtain projections of new cancer cases for that year. "Although these projections take demographic changes into account, we are unable to estimate the potential impact of changes in risk factors," co-author Professor Josep M. Borras, of the University of Barcelona, Spain, will tell the ESTRO35 conference on Sunday 1 May.

The detailed estimates for many different tumour sites produced some major increases. In breast, rectum, head and neck, lung and prostate tumours, which account for the highest percentage of patients in a radiotherapy department, there were relative increases of more than 25% in rectal patients for whom radiotherapy would be indicated in Spain, The Netherlands, and the Czech Republic, while Belgium, the UK, and Denmark had estimated increases of more than 20%.

Prostate cancer showed the highest expected increase over the period, with a 24.4% rise, followed by bladder cancer (21%) and multiple myeloma (20.4%), whereas projected increases in female breast cancer, lymphomas, and head and neck cancer were below average.

About four million new cancer patients are expected in Europe in 2025. This estimate is based on demographic changes, and represents a 15.9% increase on the 3.4 million diagnosed in 2012, assuming that overall cancer rates remain unchanged. Of these four million, the number of patients who would benefit from radiotherapy treatment at least once during the course of their disease would rise from approximately 1.7 million patients in 2012 to two million in 2025, which represents an increase of 16.1%.

This increase in new cancer cases is largely because the European population is ageing due to increased longevity and lower fertility levels. Indeed, the very old (80 years and over) now make up the fastest-growing population age group in Europe. Although migration also has an impact on demographic change, its impact is usually seen in younger age groups with a relatively lower cancer risk, the researchers say.

"Being able to estimate the number of new cancer patients requiring radiotherapy is essential if we are to be able to plan for radiotherapy services," said co-author Professor Cai Grau, from Aarhus University Hospital, Aarhus, Denmark. "We have shown clearly that the need for radiotherapy across Europe will increase substantially by the year 2025."

Professor Lievens said: "We hope that our study will focus the minds of European policymakers on the need to invest in radiotherapy, particularly as we know that there are already important differences in equipment and staff between European countries. This, taken together with the expected increase in the number of new cases of cancer, means that planning for the best possible treatment of patients needs to start now.

"ESTRO now intends to build a global partnership of organisations to help close the gap between the actual and the projected uptake of radiotherapy worldwide. A meeting to take this project forward will be held on Monday May 2 during the conference in Turin. We hope that we will able to play a major role in planning for and achieving the best possible situation for radiation oncology, and hence for patients, in the context of multidisciplinary cancer care in the future."

###

[1] "How many new cancer patients in Europe will require radiotherapy by 2025? An ESTRO-HERO analysis", by Josep M. Borras, Yolande Lievens, Michael Barton, Julieta Corral, Jacques Ferlay, Freddie Bray, Cai Grau. Radiother Oncol (2016); http://dx.doi.org/10.1016/j.radonc.2016.02.016

[2] Abstract no: OC-0331, Proffered papers: Uncovering the gap between optimal and actual utilisation of radiotherapy in Europe, 16.15-17.15 hrs (CEST) on Sunday 1 May, Room 2.

ESTRO 35 is attended by about 5000 participants from 80 countries. It features new research results in clinical radiation oncology, radiobiology, physics, technology, and brachytherapy, presented by top doctors and scientists from all over the world.

European Society for Radiotherapy and Oncology (ESTRO)


Related Radiotherapy Current Events and Radiotherapy News Articles


Vismodegib in basal cell carcinoma: Added benefit not proven
Vismodegib (trade name: Erivedge) has already been approved since 2013 for the treatment of patients with locally advanced basal cell carcinoma (BCC) or symptomatic metastatic BCC and has already undergone an early benefit assessment according to the Act on the Reform of the Market for Medicinal Products (AMNOG).

Vitamin A may help improve pancreatic cancer chemotherapy
Around 8,800 people in the UK are diagnosed with pancreatic cancer each year. It is known as the UK's deadliest cancer, with a survival rate of just 3 per cent.

Gene therapy against brain cancer
Only a few days ago, the press (especially in English-speaking countries) enthusiastically announced the publication of a study that described in great detail the genetics of breast cancer, a discovery that according to many marks a breakthrough in the battle against this cancer.

Radiotherapy halves deaths from prostate cancer 15 years after diagnosis
A longitudinal Nordic study, comparing the results of hormone (antiandrogen) therapy with or without the addition of local radiotherapy, shows that a combination of treatments halves the risk of death from prostate cancer 15 years after diagnosis.

A better way to diagnose and manage neuroendocrine tumors
A recent study reported in the May issue of the Journal of Nuclear Medicine demonstrates that Ga-68 DOTATATE PET/CT scans are superior to In-111 pentetreotide scans, the current imaging standard in the United States for detecting neuroendocrine tumors (NETS), and could significantly impact treatment management.

Improvements to online health information can help reduce barriers to care for pancreatic cancer
The Internet has become a powerful and important resource for daily life. When patients receive a medical diagnosis, particularly a difficult one like pancreatic cancer, the web can be an essential information tool, helping to enable patients to have meaningful discussions with health care providers.

Failure to publish trial results exposes patients to risks without providing benefits
Although the publication of results of clinical trials carried out in the USA within 12 months of their completion has been mandatory since 2007, an astoundingly high number of Phase III radiotherapy trials did not do so, according to new research to be presented at the ESTRO 35 conference today (Saturday).

Radiotherapy for lung cancer patients is linked to increased risk of non-cancer deaths
Researchers have found that treating patients who have early stage non-small cell lung cancer (NSCLC) with a type of radiotherapy called stereotactic body radiation therapy (SBRT) is associated with a small but increased risk of death from causes other than cancer.

UT Southwestern research shows 98 percent cure rate for prostate cancer using SBRT
A five-year study shows that Stereotactic Body Radiation Therapy (SBRT) to treat prostate cancer offers a higher cure rate than more traditional approaches, according to researchers at UT Southwestern Medical Center Harold C. Simmons Comprehensive Cancer Center.

Shortened RT schedule benefits low-risk prostate cancer patients
Of the more than 220,000 patients newly diagnosed with prostate cancer in 2015, the vast majority will have had early-stage disease at low risk for recurrence.
More Radiotherapy Current Events and Radiotherapy News Articles

Clinical Radiation Oncology, 4e

Clinical Radiation Oncology, 4e
by Leonard L. Gunderson MD MS FASTRO (Author), Joel E. Tepper MD (Author)


Perfect for radiation oncology physicians and residents needing a multidisciplinary, treatment-focused resource, this updated edition continues to provide the latest knowledge in this consistently growing field. Not only will you broaden your understanding of the basic biology of disease processes, you'll also access updated treatment algorithms, information on techniques, and state-of-the-art modalities. The consistent and concise format provides just the right amount of information, making Clinical Radiation Oncology a welcome resource for use by the entire radiation oncology team.Content is templated and divided into three sections -- Scientific Foundations of Radiation Oncology, Techniques and Modalities, and Disease Sites – for quick access to information. Disease Sites chapters...

Radiotherapy for Head and Neck Cancers: Indications and Techniques

Radiotherapy for Head and Neck Cancers: Indications and Techniques
by K. Kian Ang MD PhD (Author), Adam S. Garden MD (Author)


Long established as a staple reference for all radiation oncologists, Radiotherapy for Head and Neck Cancers: Indications and Techniques is now in its Fourth Edition. This completely updated edition presents the state-of-the-art protocols currently used at the MD Anderson Cancer Center and thoroughly explains the principles, nomenclature, and clinical use of intensity-modulated radiotherapy (IMRT). The first section discusses the practical aspects of external beam therapy, brachytherapy, and endocavitary beam therapy and offers guidelines on patient care before and during radiotherapy. The second section provides detailed coverage of site-specific indications and techniques.

Urological Complications in Gynecological Surgery and Radiotherapy (Contributions to Gynecology and Obstetrics, Vol. 11)

Urological Complications in Gynecological Surgery and Radiotherapy (Contributions to Gynecology and Obstetrics, Vol. 11)
by J. Kunz (Author)


Gynaecology & obstetrics; Radiology; Urology & urogenital medicine

Tutorials in Radiotherapy Physics: Advanced Topics with Problems and Solutions

Tutorials in Radiotherapy Physics: Advanced Topics with Problems and Solutions
by Patrick N. McDermott (Author)


The Topics Every Medical Physicist Should Know Tutorials in Radiotherapy Physics: Advanced Topics with Problems and Solutions covers selected advanced topics that are not thoroughly discussed in any of the standard medical physics texts. The book brings together material from a large variety of sources, avoiding the need for you to search through and digest the vast research literature. The topics are mathematically developed from first principles using consistent notation. Clear Derivations and In-Depth Explanations The book offers insight into the physics of electron acceleration in linear accelerators and presents an introduction to the study of proton therapy. It then describes the predominant method of clinical photon dose computation: convolution and superposition dose calculation...

Basic Radiotherapy Physics and Biology

Basic Radiotherapy Physics and Biology
by David S. Chang (Author), Foster D. Lasley (Author), Indra J. Das (Author), Marc S. Mendonca (Author), Joseph R. Dynlacht (Author)


This book is a concise and well-illustrated review of the physics and biology of radiation therapy intended for radiation oncology residents, radiation therapists, dosimetrists, and physicists. It presents topics that are included on the Radiation Therapy Physics and Biology examinations and is designed with the intent of presenting information in an easily digestible format with maximum retention in mind. The inclusion of mnemonics, rules of thumb, and reader-friendly illustrations throughout the book help to make difficult concepts easier to grasp. Basic Radiotherapy Physics and Biology is a valuable reference for students and prospective students in every discipline of radiation oncology.

Fundamentals of Medical Imaging

Fundamentals of Medical Imaging
by Paul Suetens (Author)


This third edition provides a concise and generously illustrated survey of the complete field of medical imaging and image computing, explaining the mathematical and physical principles and giving the reader a clear understanding of how images are obtained and interpreted. Medical imaging and image computing are rapidly evolving fields, and this edition has been updated with the latest developments in the field, as well as new images and animations. An introductory chapter on digital image processing is followed by chapters on the imaging modalities: radiography, CT, MRI, nuclear medicine and ultrasound. Each chapter covers the basic physics and interaction with tissue, the image reconstruction process, image quality aspects, modern equipment, clinical applications, and biological effects...

Radiotherapy Treatment Planning: Linear-Quadratic Radiobiology

Radiotherapy Treatment Planning: Linear-Quadratic Radiobiology
by J. Donald Chapman (Author), Alan E. Nahum (Author)


Understand Quantitative Radiobiology from a Radiation Biophysics Perspective In the field of radiobiology, the linear-quadratic (LQ) equation has become the standard for defining radiation-induced cell killing. Radiotherapy Treatment Planning: Linear-Quadratic Radiobiology describes tumor cell inactivation from a radiation physics perspective and offers appropriate LQ parameters for modeling tumor and normal tissue responses. Explore the Latest Cell Killing Numbers for Defining Iso-Effective Cancer Treatments The book compiles radiation mechanism information from biophysical publications of the past 50 years, addressing how ionizing radiation produces the killing of stem cells in human tumors. It presents several physical and chemical parameters that can modulate the radiation response...

  PET/CT in Radiotherapy Planning (Clinicians' Guides to Radionuclide Hybrid Imaging)
by Sue Chua (Editor)


This pocket book offers a succinct but comprehensive overview of the role of PET/CT in radiotherapy planning. Individual chapters are devoted to specific application of the technique to particular tumor types, including non-small cell lung, gastrointestinal, head and neck squamous cell, prostate, gynecological, and pediatric tumors. Helpful information is also presented on the practical implementation of PET/CT in routine oncological practice. Technical and logistical issues are discussed, and guidance provided on potential problems and pitfalls and available solutions. The book will be invaluable in assisting readers to exploit PET/CT’s ability to significantly improve delineation of tumor tissue through the addition of metabolic information to structural imaging data, thereby avoiding...

Handbook of Radiotherapy Physics: Theory and Practice

Handbook of Radiotherapy Physics: Theory and Practice
by CRC Press


From background physics and biological models to the latest imaging and treatment modalities, the Handbook of Radiotherapy Physics: Theory and Practice covers all theoretical and practical aspects of radiotherapy physics.

In this comprehensive reference, each part focuses on a major area of radiotherapy, beginning with an introduction by the editors and then subdividing into self-contained chapters. The first three parts present the fundamentals of the underlying physics, radiobiology, and technology involved. The ensuing sections discuss the support requirements of external beam radiotherapy, such as dose measurements, properties of clinical beams, patient dose computation, treatment planning, and quality assurance, followed by a part that explores exciting new advances that...

Practical Radiotherapy Planning Fourth Edition

Practical Radiotherapy Planning Fourth Edition
by CRC Press


Planning is a critical stage of radiotherapy. Careful consideration of the complex variables involved and critical assessment of the techniques available are fundamental to good and effective practice.

First published in 1985, Practical Radiotherapy Planning has, over three editions, established itself as the popular choice for the trainee raditation oncologist and radiographer, providing the 'nuts and bolts' of planning in a practical and accessible manner.

This fourth edition encompasses a wealth of new material, reflecting the radical change in the practice of radiotherapy in recent years. The information contained within the introductory chapters has been expanded and brought up to date, and a new chapter on patient management has been added. CT stimulators, MLC...

© 2017 BrightSurf.com