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Novel type 2 diabetes risk model more accurately assesses disease trajectory

June 01, 2016

An innovative model for determining a person's risk of developing type 2 diabetes (T2D) overcomes many of the challenges associated with estimating the onset of a chronic condition based on the usual sequence of comorbid conditions that lead up to a diagnosis of T2D. In addition to identifying a typical T2D trajectory, the new model has shown that people who follow atypical trajectories can face significantly increased or decreased risks of developing T2D, according to an article in Big Data, the highly innovative, peer-reviewed journal from Mary Ann Liebert, Inc., publishers. The article is available free for download on the Big Data website until July 1, 2016.

In the article "Type 2 Diabetes Mellitus Trajectories and Associated Risks," Wonsuk Oh, Gyorgy Simon, and coauthors from University of Minnesota, Minneapolis and Mayo Clinic, Rochester, MN, focus on three important comorbidities that are part of the progression to T2D: hyperlipidemia, hypertension, and impaired fasting glucose. The researchers used large-scale data analytics to study data collected from electronic health record (EHR) systems. The available of EHR data and a large sample size makes it possible to build fine-grain disease progression models that are increasingly accurate and provide more personalized assessments.

"Diseases such as diabetes have seen a surge in many parts of the world, driven by changing diets and lifestyles," says Big Data Editor-in-Chief Vasant Dhar, Professor at the Stern School of Business and the Center for Data Science at New York University. "It has become critical that we detect warning patterns early so that actions can be taken to stave off negative health outcomes. The article by Oh et.al makes significant progress in this direction."

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About the Journal

Big Data, published quarterly online with open access options and in print, facilitates and supports the efforts of researchers, analysts, statisticians, business leaders, and policymakers to improve operations, profitability, and communications within their organizations. Spanning a broad array of disciplines focusing on novel big data technologies, policies, and innovations, the Journal brings together the community to address the challenges and discover new breakthroughs and trends living within this information. Complete tables of content and a sample issue may be viewed on the Big Data website.

About the Publisher

Mary Ann Liebert, Inc., publishers is a privately held, fully integrated media company known for establishing authoritative medical and biomedical peer-reviewed journals, including OMICS: A Journal of Integrative Biology, Journal of Computational Biology, New Space, and 3D Printing and Additive Manufacturing. Its biotechnology trade magazine, GEN (Genetic Engineering & Biotechnology News), was the first in its field and is today the industry's most widely read publication worldwide. A complete list of the firm's more than 80 journals, newsmagazines, and books is available on the Mary Ann Liebert, Inc., publishers website.

Mary Ann Liebert, Inc./Genetic Engineering News


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