Novel type 2 diabetes risk model more accurately assesses disease trajectoryJune 01, 2016
An innovative model for determining a person's risk of developing type 2 diabetes (T2D) overcomes many of the challenges associated with estimating the onset of a chronic condition based on the usual sequence of comorbid conditions that lead up to a diagnosis of T2D. In addition to identifying a typical T2D trajectory, the new model has shown that people who follow atypical trajectories can face significantly increased or decreased risks of developing T2D, according to an article in Big Data, the highly innovative, peer-reviewed journal from Mary Ann Liebert, Inc., publishers. The article is available free for download on the Big Data website until July 1, 2016.
In the article "Type 2 Diabetes Mellitus Trajectories and Associated Risks," Wonsuk Oh, Gyorgy Simon, and coauthors from University of Minnesota, Minneapolis and Mayo Clinic, Rochester, MN, focus on three important comorbidities that are part of the progression to T2D: hyperlipidemia, hypertension, and impaired fasting glucose. The researchers used large-scale data analytics to study data collected from electronic health record (EHR) systems. The available of EHR data and a large sample size makes it possible to build fine-grain disease progression models that are increasingly accurate and provide more personalized assessments.
"Diseases such as diabetes have seen a surge in many parts of the world, driven by changing diets and lifestyles," says Big Data Editor-in-Chief Vasant Dhar, Professor at the Stern School of Business and the Center for Data Science at New York University. "It has become critical that we detect warning patterns early so that actions can be taken to stave off negative health outcomes. The article by Oh et.al makes significant progress in this direction."
About the Journal
Big Data, published quarterly online with open access options and in print, facilitates and supports the efforts of researchers, analysts, statisticians, business leaders, and policymakers to improve operations, profitability, and communications within their organizations. Spanning a broad array of disciplines focusing on novel big data technologies, policies, and innovations, the Journal brings together the community to address the challenges and discover new breakthroughs and trends living within this information. Complete tables of content and a sample issue may be viewed on the Big Data website.
About the Publisher
Mary Ann Liebert, Inc., publishers is a privately held, fully integrated media company known for establishing authoritative medical and biomedical peer-reviewed journals, including OMICS: A Journal of Integrative Biology, Journal of Computational Biology, New Space, and 3D Printing and Additive Manufacturing. Its biotechnology trade magazine, GEN (Genetic Engineering & Biotechnology News), was the first in its field and is today the industry's most widely read publication worldwide. A complete list of the firm's more than 80 journals, newsmagazines, and books is available on the Mary Ann Liebert, Inc., publishers website.
Mary Ann Liebert, Inc./Genetic Engineering News
Related Diabetes Current Events and Diabetes News Articles
Leaky blood-brain barrier linked to Alzheimer's disease
Researchers using contrast-enhanced MRI have identified leakages in the blood-brain barrier (BBB) of people with early Alzheimer's disease (AD), according to a new study published online in the journal Radiology.
Researchers suggest whole-person perspective is needed to assess obesity
Authors from the Cleveland Clinic's Bariatric and Metabolic Institute recommend physicians use obesity staging models to recognize and manage weight-related health issues that may not be captured by traditional diagnosis criteria.
Autism care improved, diagnosis time shortened by new MU program
Wait lists for a specialist to confirm an autism diagnosis can be agonizing and last months. As the prevalence of autism and autism spectrum disorders increase, so does the demand for a health care system that is fully equipped to respond to the complex needs associated with autism.
Newly discovered gene regulates hyperglycemia-induced beta cell death in type 2 diabetes
It's no secret that over time, elevated levels of blood glucose (hyperglycemia) can induce the death of the pancreatic beta cells.
Study show female heart patients less likely to get blood thinning therapy
Female atrial fibrillation patients are less likely than their male counterparts to receive blood thinning therapies to prevent stroke, say University of Cincinnati College of Medicine researchers.
Ancient anti-inflammatory drug salicylic acid has cancer-fighting properties
Scientists from the Gladstone Institutes have identified a new pathway by which salicylic acid--a key compound in the nonsteroidal anti-inflammatory drugs aspirin and diflunisal--stops inflammation and cancer.
New study uncovers mechanisms underlying how diabetes damages the heart
Cardiac complications are the number one cause of death among diabetics. Now a team of scientists has uncovered a molecular mechanism involved in a common form of heart damage found in people with diabetes.
PNNL helps lead national microbiome initiative
Scientists at the U.S. Department of Energy's Pacific Northwest National Laboratory are playing a central role as the nation devotes more than $500 million to understand communities of microorganisms and their role in climate science, food production and human health.
Study finds one third of children have higher levels of cardiometabolic risk factors due to family history
A new study published in Diabetologia (the journal of the European Association for the Study of Diabetes [EASD]) shows that children with a strong family history of cardiovascular disease (CVD) and/or type 2 diabetes were found to have cholesterol levels significantly higher than children with no family history of those conditions.
Gut bacteria may contribute to poor health in patients with kidney disease
In patients with chronic kidney disease (CKD), the accumulation of a gut bacterial metabolite that's normally excreted in urine may contribute to serious health problems.
More Diabetes Current Events and Diabetes News Articles