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Concern over clinical value of new mood disorder drugs
July 16, 2003Recent changes to the classification of psychiatric disorders are encouraging pharmaceutical companies to develop new drugs that are of questionable clinical value, argue researchers in this week’s BMJ.
Since 1980, anxiety and depression have been split into separate diseases. Drug development has subsequently been tailored to new “niche” diagnoses such as panic, social anxiety disorder, and post-traumatic stress disorder.
The proliferation of niche diagnoses is liked by industry because it creates new licensing opportunities for phoney new drugs, but it has also led to a slowdown in production of drugs for the most common psychiatric disorder of mixed anxiety and depression, write the authors.
“We believe that the failure to advance the treatment of anxiety and depression is related to wrong classification,” say the authors.
Companies must start developing drugs for mixed anxiety and depression and forget about dividing this giant illness segment into salami slices. Doctors could encourage this change by being more cynical about pitches from drug representatives claiming to have “the latest” medication to reduce anxiety, they conclude.
British Medical Journal (BMJ)
“We believe that the failure to advance the treatment of anxiety and depression is related to wrong classification,” say the authors.
Companies must start developing drugs for mixed anxiety and depression and forget about dividing this giant illness segment into salami slices. Doctors could encourage this change by being more cynical about pitches from drug representatives claiming to have “the latest” medication to reduce anxiety, they conclude.
British Medical Journal (BMJ)
Depression Current Events and Depression News RSSNew TMS clinic offers noninvasive treatment for major depression
Rush University Medical Center has opened the Transcranial Magnetic Stimulation (TMS) Clinic to offer patients suffering from major depression a safe, effective, non-drug treatment.
Discrimination takes its toll on Black women
Racial discrimination is a major threat to African American women's mental health. It undermines their view of themselves as masters of their own life circumstances and makes them less psychologically resilient and more prone to depression.
American Dietetic Association Releases Updated Position Paper Promoting and Supporting Breastfeeding
The American Dietetic Association has released an updated position paper on breastfeeding that details health benefits for both infants and mothers and encourages promotion of breastfeeding whenever possible.
New therapy gives hope for very severe depression
Thanks to a new method there is a reason for hope for patients with very severe depression. Physicians at the University Clinics of Bonn and Cologne have treated ten patients with deep brain stimulation.
Study shows that sleep disturbances improve after retirement
A study in the Nov.1 issue of the journal Sleep shows that retirement is followed by a sharp decrease in the prevalence of sleep disturbances. Findings suggest that this general improvement in sleep is likely to result from the removal of work-related demands and stress rather than from actual health benefits of retirement.
Pregnant women risk early delivery from using psychiatric medication
The odds triple for premature child delivery pregnant women with a history of depression who used psychiatric medication, according to a new study.
Stress-induced changes in brain circuitry linked to cocaine relapse
Stress-evoked changes in circuits that regulate serotonin in certain parts of the brain can precipitate a low mood and a relapse in cocaine-seeking, based on mouse studies published online this week in the Proceedings of the National Academy of Sciences.
Benefit of memantine in the treatment of Alzheimer's disease not proven
There is no scientific proof that patients with moderate or severe Alzheimer's disease benefit from drugs containing the agent memantine.
Member of NFL Hall of Fame diagnosed with degenerative brain disease
The Center for the Study of Traumatic Encephalopathy (CSTE) at Boston University School of Medicine (BUSM) announced today that a recently deceased member of the NFL Hall of Fame suffered from the degenerative brain disease Chronic Traumatic Encephalopathy (CTE) when he died, becoming the 10th former NFL player diagnosed with the disease.
Adolescents think school bullying 'will keep on happening' and resign themselves to it
Most of the adolescents think that bullying in the school context "has always happened and will continue happening", and present "a negative, pessimistic and resigned attitude" towards this social problem, which makes difficult the intervention and leaves few hopes for its eradication.
More Depression Current Events and Depression News Articles
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The Mindful Way through Depression: Freeing Yourself from Chronic Unhappiness by Mark Williams (Author), John Teasdale (Author), Zindel Segal (Author), Jon Kabat-Zinn (Author) The Mindful Way through Depression draws on the collective wisdom of four internationally renowned cognitive therapy and mindfulness experts, including bestselling author Jon Kabat-Zinn, to help you break the mental habits that can lead to despair. This authoritative, easy-to-use self-help program is based on methods clinically proven to reduce the recurrence of chronic unhappiness. Informative chapters reveal the hidden psychological mechanisms that cause depression and demonstrate powerful ways to strengthen your resilience in the face of life's misfortunes. Kabat-Zinn lends his calm, familiar voice to the accompanying CD of guided meditations, making this a complete package for anyone looking to regain a sense of balance and contentment. |
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The Cognitive Behavioral Workbook for Depression: A Step-by-step Program (Workbook) by William J. Knaus (Author), Albert Ellis (Foreword) In the 1950s, Albert Ellis pioneered a form of psychotherapy that combined ways of detecting and changing irrational thoughts with techniques for replacing negative behaviors with positive ones. This type of cognitive behavioral therapy, called rational emotive behavior therapy (REBT) by Ellis, proved especially effective at relieving problems like anger, anxiety, and depression. In this book author William Knaus, a close associate of Ellis, develops the best REBT techniques into a powerful and comprehensive self-help workbook for the treatment of depression. Following in New Harbinger’s tradition, this workbook is written in an easy-to-use, step-by-step format. It offers you powerful strategies for overcoming depression in simple, direct language, amply illustrated with stories... |
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Talking to Depression: Simple Ways To Connect When Someone In Your Life Is Depressed by Claudia J. Strauss (Author), Martha Manning (Foreword) When someone suffers from depression, friends and family members naturally want to help-but too often their good intentions come out all wrong. This practical, compassionate guide helps readers understand exactly what their loved one is going through, and why certain approaches help and others have the potential to do damage. Talking to Depression offers specific advice on what to do and what not to do-and what to say and what not to say-to avoid frustration and give the kind of caring, effective support that will make a difference. |
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Undoing Depression: What Therapy Doesn't Teach You and Medication Can't Give You by Richard O'Connor (Author) Like heart disease, says psychotherapist Richard O'Connor, depression is fueled by complex and interrelated factors: genetic, biochemical, environmental. In this refreshingly sensible book, O'Connor focuses on an additional factor often overlooked: our own habits. Unwittingly we get good at depression. We learn how to hide it, how to work around it. We may even achieve great things, but with constant struggle rather than satisfaction. Relying on these methods to make it through each day, we deprive ourselves of true recovery, of deep joy and healthy emotion. UNDOING DEPRESSION teaches us how to replace depressive patterns with a new and more effective set of skills. We already know how to "do" depression-and we can learn how to undo it. With a truly holistic approach that... |
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Self-Coaching: The Powerful Program to Beat Anxiety and Depression, 2nd Edition, Completely Revised and Updated by Joseph J. Luciani (Author) The simple, untold truth about anxiety and depression is that they are habits of insecurity—and, like all habits, they can be broken. In this new edition of the highly successful Self-Coaching, Dr. Joseph Luciani shows you how to change your way of thinking and develop a healthy, adaptive way of living through his proven Self-Talk strategy for coaching yourself back to health. |
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Overcoming Depression One Step at a Time: The New Behavioral Activation Approach to Getting Your Life Back (New Harbinger Self-Help Workbook) by Michael E., Ph.D. Addis (Author), Christopher R. Martell (Author) Learn breakthrough self-activation techniques to: ·Become more engaged with your life ·Enjoy daily activities ·Feel able to face challenges ·Stop avoiding social situations ·Feel strong and competent again ·Conquer the obstacles that keep depression going ·Stop making decisions based on your moods ·Get back on track with your life goals ·Recognize the habits and patterns that fuel your depression Achieve medication-free recovery Behavioral activation therapy offers effective, fast relief from depression. This powerful and progressive therapy steers away from the idea that depression symptoms represent an illness or weakness. Instead, depression is merely a signpost pointing directly at the things that need to change in one's life. Its engaging... |
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Depression: A Stubborn Darkness--Light for the Path (VantagePoint Books) by Edward T. Welch (Author) Depression: A Stubborn Darkness is Dr. Edward T. Welch s latest release in a series of ground-breaking best-selling counseling books that include When People Are Big and God is Small, Blame It on the Brain?, Addictions: A Banquet in the Grave. Now in its third printing, Welch continues to further his reputation as an author who can speak to general consumers in a language they intuitively connect with on a deeply personal level. Endorsed by Joni Eareckson Tada, and Bob Lepine of FamilyLife, this book is targeted to the 18 million adult Americans who struggle with depression. Compassionate and compelling, the book lays out issues and answers with Welch s world view that faith needs to be interlaced with therapies and medication for conditions categorized as strictly clinical. The author... |
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Amoryn Depression Anxiety Relief (60 Caps) by BioNeurix AMORYN works by increasing the levels of all four of the brain's "feel good" neurotransmitters. By providing an all-natural boost to serotonin, dopamine, norepinephrine, and GABA, the ingredients in AMORYN can help you feel happy, calm, and confident.serotonin levels. As a precursor to serotonin, 5-HTP provides the brain with the "building blocks" needed to produce more serotonin naturally. |
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Depression Fallout: The Impact of Depression on Couples and What You Can Do to Preserve the Bond by Anne Sheffield (Author) What happens to love when a partner is depressed? Is your partner's depression undermining your happiness as a couple? After blaming yourself, losing your self-esteem, and getting angry, you may feel like walking away -- even if you're still in love. With 19 million Americans suffering from depression, you are not alone in your unhappiness. And no one knows what you're going through better than Anne Sheffield, who coined the phrase "depression fallout" in her first book, How You Can Survive When They're Depressed, to describe the emotional toll of depression on spouses, parents, lovers, and children.Sharing essential information, compassion, and street-smart advice, Anne Sheffield tells you: What you need to know about your partner's mental health and what to do about... |
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Depression-Free, Naturally: 7 Weeks to Eliminating Anxiety, Despair, Fatigue, and Anger from Your Life by Joan Mathews Larson (Author) In this groundbreaking book, nutritionist Joan Mathews Larson, Ph.D., founder of Minnesota's esteemed Health Recovery Center, offers her revolutionary formulas for healing your emotions--biochemically. Through proven all-natural formulas, Seven Weeks to Emotional Healing will help you find the emotional well-being you've been missing your entire life. Inside you'll discover how to - Screen yourself for emotional and behavioral symptoms - Recognize the mental and physical clues that indicate biochemical imbalances - Heal your depression and anxiety with the right vitamins and minerals - Stabilize your mood swings and protect your well-being with essential fatty acids - Choose the right foods for optimal mental fitness - Rejuvenate your body with key natural... |
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