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Birth weight may be linked to arthritis in later life
May 14, 2003The cause of rheumatoid arthritis is unknown, but researchers in this week’s BMJ suggest that some factors relating to the period shortly before and after birth (perinatal factors) may be implicated in the development of the disease in later life.
Researchers in Sweden identified 77 patients with rheumatoid arthritis and 308 matched controls. Using birth records, they collected information such as birth weight, mother’s age, length of hospital stay after delivery, start of breast feeding during the hospital stay, and father’s occupation (manual or non-manual worker).
They found that high birth weight (4000g or more) was positively associated with rheumatoid arthritis but low birth weight was not. Initiation of breast feeding during the hospital stay and the father’s occupation were also associated with rheumatoid arthritis. They found no other significant associations.
“Our findings indicate that characteristics of the perinatal period may be of aetiological importance in the pathogenesis of rheumatoid arthritis,” they conclude.
British Medical Journal (BMJ)
“Our findings indicate that characteristics of the perinatal period may be of aetiological importance in the pathogenesis of rheumatoid arthritis,” they conclude.
British Medical Journal (BMJ)
Arthritis News and Current Arthritis Events RSSStudy shows pine bark naturally reduces knee osteoarthritis
According to the Center for Disease Control (CDC), osteoarthritis, the most common type of arthritis, is on the rise. A new study published in the August journal of Phytotherapy Research, reveals Pycnogenol, bark extract from the French maritime pine tree, reduced overall knee osteoarthritis (OA) symptoms by 20.9 percent and lowered pain by 40.3 percent.
Loss of sleep, even for a single night, increases inflammation in the body
Loss of sleep, even for a few short hours during the night, can prompt one's immune system to turn against healthy tissue and organs.
Nearly half of U.S. adults will develop painful knee osteoarthritis by age 85: study
Almost half of all U.S. adults and nearly two-thirds of obese adults will develop painful osteoarthritis of the knee by age 85, a study based at the University of North Carolina at Chapel Hill suggests.
Cell removal technique could lead to cheaper drugs
Researchers at the University of Edinburgh have pioneered a simple way to remove dead cells from cell cultures used to make protein-based drugs, which are increasingly prescribed to treat a range of illnesses.
New study shows health benefits of probiotic could extend to the entire body
Data from a recent study demonstrate the anti-inflammatory and pathogen protection benefits of Bifidobacterium infantis 35624 a probiotic bacterial strain of human origin.
Bone marrow stem cells may help control inflammatory bowel disease
Massachusetts General Hospital (MGH) investigators have found that infusions of a particular bone marrow stem cell appeared to protect gastrointestinal tissue from autoimmune attack in a mouse model.
Researchers discover how rheumatoid arthritis causes bone loss
Researchers have discovered key details of how rheumatoid arthritis (RA) destroys bone, according to a study published in the Aug. 22 edition of the Journal of Biological Chemistry.
New test to diagnose osteoarthritis early
A newly developed medical imaging technology may provide doctors with a long-awaited test for early diagnosis of osteoarthritis (OA), scientists from New York reported today at the 236th National Meeting of the American Chemical Society.
NIH scientists find a novel mechanism that controls the development of autoimmunity
Scientists at the National Institutes of Health (NIH) have found a mechanism in the immune systems of mice that can lead to the development of autoimmune disease when turned off.
Protein complementarity may offer new insights into autoimmune diseases
The discovery of "complementary" antibodies against plasminogen in patients with blood vessel inflammation caused by anti-neutrophil cytoplasmic autoantibodies (ANCAs) may lead to new approaches to research, testing, and treatment of ANCA vasculitis and other autoimmune diseases, suggests a paper in the December Journal of the American Society of Nephrology (JASN).
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