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Inhaled asthma drugs more effective than oral therapy
March 19, 2003Inhaled glucocorticoid drugs are more effective than the newer anti-leukotriene tablets for adults with mild or moderate asthma, concludes a study in this week’s BMJ.
Professor Francine Ducharme reviewed 13 trials comparing leukotriene receptor antagonists with low doses of inhaled glucocorticoids for 28 days or more in children and adults.
She found that adults treated with leukotriene receptor antagonists were 60% more likely to suffer worsening of symptoms, whereas those treated with inhaled glucocorticoids experienced fewer night awakenings and fewer days with symptoms.
Risk of side effects was no different between groups, but leukotriene receptor antagonists were associated with a 2.5-fold increase risk of withdrawal because of poor asthma control.
There was insufficient evidence to draw conclusions about effectiveness in children.
British Medical Journal (BMJ)
Risk of side effects was no different between groups, but leukotriene receptor antagonists were associated with a 2.5-fold increase risk of withdrawal because of poor asthma control.
There was insufficient evidence to draw conclusions about effectiveness in children.
British Medical Journal (BMJ)
Asthma Current Events and Asthma News RSSFree e-samples of prescription drugs: At what cost?
Search the Internet to learn about your asthma, high cholesterol or other common disorder, and odds are you'll be directed to a pharmaceutical company-sponsored Web homepage.
Parent mentors can improve the asthmatic care of minority children, UT Southwestern researchers find
UT Southwestern Medical Center researchers have found that informed adults can help families stave off complications associated with asthma.
Exposures to metals and diesel emissions in air linked to respiratory symptoms in children
Exposure shortly after birth to ambient metals from residential heating oil combustion and particles from diesel emissions are associated with respiratory symptoms in young inner city children.
Exposure to both traffic, indoor pollutants puts some kids at higher risk for asthma later
New research presents strong evidence that the "synergistic" effect of early-life exposure to both outdoor traffic-related pollution and indoor endotoxin causes more harm to developing lungs than one or the other exposure alone.
Johns Hopkins researchers track down protein responsible for chronic rhinosinusitis with polyps
A protein known to stimulate blood vessel growth has now been found to be responsible for the cell overgrowth in the development of polyps that characterize one of the most severe forms of sinusitis, a study by Johns Hopkins researchers suggests.
Ancestry attracts, but love is blind
People preferentially marry those with similar ancestry, but their decisions are not necessarily based on hair, eye or skin colour.
Common plastics chemicals linked to ADHD symptoms
Phthalates are important components of many consumer products, including toys, cleaning materials, plastics, and personal care items.
Asthma a significant risk factor for complications in children with H1N1
A new study on pediatric H1N1 influenza admissions has found that asthma is a significant risk factor for severe disease in children with pandemic H1N1 compared with the seasonal flu.
Mother's Depression a Risk Factor in Childhood Asthma Symptoms, Study Suggests
Asthma symptoms can worsen in children with depressed mothers, according to research from Johns Hopkins Children's Center published online in the Journal of Pediatric Psychology.
Sweet -- sugared polymer a new weapon against allergies and asthma
Scientists at Johns Hopkins and their colleagues have developed sugar-coated polymer strands that selectively kill off cells involved in triggering aggressive allergy and asthma attacks.
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Primatene Mist Epinephrine Inhalation Aerosol Bronchodilator with Mouthpiece for Oral Inhalation, .5 fl oz (15 ml) by Primatene For the temporary relief of Bronchial Asthma. Contains no sulfites. Made in USA. |
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