 |
|
The Lancet Neurology - January 2003
December 18, 2002STROKE IN THE 21st CENTURY
In the first issue of 2003, TLN examines stroke epidemiology and stroke trials. In their review, Valery Feigin and co-authors provide an overview of population-based studies of incidence, prevalence, mortality, and case-fatality of stroke based on studies reported between 1996 and 2002. From their analysis the authors conclude, "the burden of stroke is high and is likely to increase in future decades as a result of demographic and epidemiological transitions in populations". In an accompanying personal view, Ken Lees, Graeme Hankey, and Werner Hacke discuss the designs and results of all controlled trials of treatments for ischaemic stroke, and try to identify opportunities to improve future treatment assessment.
STATINS FOR THE TREATMENT OF MULTIPLE SCLEROSIS
In a Reflection & Reaction article, John Greenwood and colleagues discuss the evidence supporting a role for statins-such as lovastatin and atorvastatin-in the treatment of multiple sclerosis by the prevention of CNS leucocyte accumulation. Since the mechanism of action of statins differs from that of currently approved treatments, there may be some benefit in a combination approach.
MILD COGNITIVE IMPAIRMENT
Mild cognitive impairment is a recently adopted term to describe the transition between healthy ageing and dementia. In a review article, Charles DeCarli discusses the prevalence, pathophysiology, prognosis, and possibilities for the treatment of this condition. "Current estimates suggest that many people have various cognitive impairments that will substantially increase their risk of developing dementia, hence the urgent need to identify and treat these disorders", he writes.
OTHER REVIEWS:
Lancet
Multiple Sclerosis Current Events and Multiple Sclerosis News RSSMelatonin may save eyesight in inflammatory disease
Current research suggests that melatonin therapy may help treat uveitis, a common inflammatory eye disease. The related report by Sande et al., "Therapeutic Effect of Melatonin in Experimental Uveitis," appears in the December issue of The American Journal of Pathology.
Researcher tricks immune system in diabetic mice
The body's immune system hates strangers. When its security patrol spots a foreign cell, it annihilates it.
In the war against diseases, nerve cells need their armor
In a new study, researchers at the Montreal Neurological Institute (MNI), McGill University, and the Université de Montréal have discovered an essential mechanism for the maintenance of the normal structure of myelin, the protective covering that insulates and supports nerve cells (neurons).
Intraspinal implant of mesenchymal stem cells may not heal the demyelinated spinal cord
Multiple sclerosis is a disease caused by the loss of the myelinated sheath surrounding the nerve fibers of the spinal cord.
Multiple sclerosis research charges ahead with new mouse model of disease
A new study highlights the role of a charge-switching enzyme in nervous system deficits characteristic of multiple sclerosis and other related neurological illness.
Lung airway cells activate vitamin D and increase immune response
Vitamin D is essential to good health but needs to be activated to function properly in the human body. Until recently, this activation was thought to happen primarily in the kidneys, but a new University of Iowa study finds that the activation step can also occur in lung airway cells.
Type-1 diabetes not so much bad genes as good genes behaving badly, Stanford research shows
Investigators combing the genome in the hope of finding genetic variants responsible for triggering early-onset diabetes may be looking in the wrong place, new research at the Stanford University School of Medicine suggests.
Phase IIb data show that BG-12 significantly reduced brain lesions in multiple sclerosis
Biogen Idec (NASDAQ: BIIB) today announced the publication of Phase IIb data showing that a 240 mg three-times-daily dose of the company's novel oral compound, BG-12 (BG00012, dimethyl fumarate), reduced the number of new gadolinium enhancing (Gd+) lesions by 69 percent in patients with relapsing-remitting multiple sclerosis (MS) when compared to treatment with placebo (p<0.0001).
New hope for multiple sclerosis sufferers
A drug which was developed in Cambridge and initially designed to treat a form of leukaemia has also proven effective against combating the debilitating neurological disease multiple sclerosis (MS).
Genetic analysis predicts whether liver cancer likely to recur
Researchers are poised to unlock the genetic secrets stored in hundreds of thousands of cancer biopsy samples locked in long-term storage and previously thought to be useless for modern genetic research.
More Multiple Sclerosis Current Events and Multiple Sclerosis News Articles
 | Multiple Sclerosis Q & A: Researching Answers to Frequently Asked Questions by Beth Ann Hill An insightful, informative, and empathic resource for learning to live well with multiple sclerosis. This comprehensive yet accessible work provides authoritative and reassuring answers to the many questions that overwhelm those undergoing testing and treatment for multiple sclerosis. It discusses traditional and complementary therapies for MS; explains medical terminology and diagnostics; and... |
 | The First Year: Multiple Sclerosis: An Essential Guide for the Newly Diagnosed (The First Year) by Margaret Blackstone One of the most widely recommended guides to living with multiple sclerosis, now completely revised and updated, including the latest research, the most recent information on treatments (including the news on Tysabri®), and new tips for managing MS. Multiple sclerosis is as much a mystery as it is a disease, but this chronic and often disabling condition of the central nervous system affects... |
 | Healing Multiple Sclerosis: Diet, Detox & Nutritional Makeover for Total Recovery by Ann Boroch Multiple Sclerosis can now be healed and this book shows you how. Though MS is widely believed to be incurable, Boroch's breakthrough treatment protocol can dramatically restore patients to health. This landmark book describes her own tumultuous journey with MS: • Her quest for a cure • Case histories of those who have triumphed over MS • The real causes of MS • How to develop a... |
 | Multiple Sclerosis: The Guide to Treatment and Management by Chris H. Polman This completely revised edition of the best-selling Multiple Sclerosis: The Guide to Treatment and Management is a comprehensive, accessible guide to the present therapeutic options and their efficacy. Special features include expert opinion statements for each MS therapy; a unique guide to the wide diversity of therapeutic options available; a thorough discussion of the usefulness,... |
 | Exercises for Multiple Sclerosis: A Safe and Effective Program to Fight Fatigue, Build Strength, and Improve Balance (Exercises for) by Brad Hamler Fight the impact of MS through fitness with specially designed exercises.In the U.S. alone, approximately 400,000 people have multiple sclerosis (MS). MS is an autoimmune disease that affects the central nervous system. There are a variety of symptoms of MS and it affects people in different ways, but there is no cure.Fitness can help strengthen debilitated bodies, and make living with the... |
 | Multiple Sclerosis: Your Legal Rights by Lanny E. Perkins, Sara D. Perkins In the past seven years, since the publication of the last edition, significant legislative changes have taken place that affect the lives of anyone living with MS. Trying to decipher new laws can be overwhelming, even for the most educated individual. This updated edition of a comprehensive legal reference for MS patients incorporates recent legislative changes affecting MS patients. The book... |
 | When the Diagnosis Is Multiple Sclerosis: Help, Hope, and Insights from an Affected Physician by Kym Orsetti Furney Kym Orsetti Furney was a 34-year-old physician, specializing in Internal Medicine, busy with her exciting job and enjoying life with her husband and young daughter in 2000, when she suddenly began to experience dizziness repeatedly, which rapidly led to a diagnosis of Multiple Sclerosis. Her world was rocked for a time, but Furney has recovered from the shock and--empowered by information,... |
 | The MS Workbook: Living Fully With Multiple Sclerosis by George H., M.D. Kraft, Dawn M., Ph.D. Ehde, Kurt L., Ph.D. Johnson Multiple sclerosis (MS) can be a terrifying diagnosis for anyone to face. But, as with many other potentially devastating problems, MS can be best controlled and best lived with when sufferers balance prudent lifestyle changes with effective treatment—and these sorts of choices require sound and current information. This workbook, written by a team of doctors and psychologists from the renowned... |
 | Reversing Multiple Sclerosis: 9 Effective Steps to Recover Your Health by Celeste Pepe, Lisa Hammond Reversing Multiple Sclerosis 9 Effective Steps to Recover Your Health Celeste Pepe, D.C., N.D. and Lisa Hammond Celeste Pepe was strong, fit, and energetic until multiple sclerosis attacked. The verdict: incurable. The option: masking symptoms with synthetic drugs that did nothing to reverse the disease and often produced debilitating side effects. Instead, Pepe sought alternative... |
 | Facing the Cognitive Challenges of Multiple Sclerosis by Jeffrey N. Gingold |
| © 2008 BrightSurf.com |