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Further Evidence That Hrt Does Not Protect Against Cardiovascular Disease (p 2001)
December 18, 2002Results of a UK randomised trial published in this week's issue of THE LANCET provides further evidence that hormone replacement therapy (HRT) does not offer women protection against cardiovascular disease.
Previous observational studies have suggested that HRT could reduce the risk of coronary heart disease (CHD), but results of randomised trials do not suggest a lower risk in women who use combination oestrogen/progestagen therapy. A team of scientists from the University of Manchester, UK, assessed whether or not oestrogen reduced the risk of further cardiac events in postmenopausal women who survived a first heart attack.
Around 1000 postmenopausal women, age 50-69 years who had survived a first heart attack were recruited from 35 hospitals in England and Wales. They were given either one daily tablet of 2 mg oestradiol valerate or placebo for two years. There was no difference in the frequency of recurrent heart attack or cardiac death at follow-up, and the difference in all-cause mortality (lower among women given oestrogen therapy) was not statistically significant.
Nicola Cherry, the principal investigator, comments: "Oestrogen therapy does not reduce the overall risk of further cardiac events in postmenopausal women who have survived aheart attack. This study provides insufficient evidence of benefit to alter current guidance against the use of HRT for the secondary prevention of cardiovascular disease."
See also Commentary - 'Hormones for coronary disease-full circle' (p 1996).
Lancet
Nicola Cherry, the principal investigator, comments: "Oestrogen therapy does not reduce the overall risk of further cardiac events in postmenopausal women who have survived aheart attack. This study provides insufficient evidence of benefit to alter current guidance against the use of HRT for the secondary prevention of cardiovascular disease."
See also Commentary - 'Hormones for coronary disease-full circle' (p 1996).
Lancet
Estrogen Current Events and Estrogen News RSSHeart and bone damage from low vitamin D tied to declines in sex hormones
Researchers at Johns Hopkins are reporting what is believed to be the first conclusive evidence in men that the long-term ill effects of vitamin D deficiency are amplified by lower levels of the key sex hormone estrogen, but not testosterone.
Fertility procedures need not delay breast cancer treatment for younger women
A new study published in the November issue of the Journal of the American College of Surgeons shows that breast cancer patients under 40 years old who undergo fertility preservation do not face a significant delay in the treatment of their disease when their care is coordinated in a timely fashion.
Coffee break: Compound brewing new research in colon, breast cancer
A compound in coffee has been found to be estrogenic in studies by Texas AgriLife Research scientists.
Mayo researchers find robotic repair for vaginal prolapse has significant benefits
New Mayo Clinic research has found that robotic surgery for vaginal prolapse dramatically reduces patient hospital stay and recovery time.
Estrogen therapy likely must be given soon after menopause to provide stroke protection
For estrogen replacement to provide stroke protection, it likely must be given soon after levels drop because of menopause or surgical removal of the ovaries, scientists report in the Journal of Neuroscience.
Oral contraceptives may benefit women with asthma
New research shows that during natural menstrual cycles, women with asthma who were not taking oral contraceptives (OC) had lower exhaled nitric oxide levels (eNO), a marker of airway inflammation associated with asthma, than women who were taking OC.
Study shows hormone replacement therapy decreases mortality in younger postmenopausal woman
Hormone replacement therapy (HRT) to treat menopausal estrogen deficiency has been in widespread use for over 60 years. Several observational studies over the years showed that HRT use by younger postmenopausal women was associated with a significant reduction in total mortality; available evidence supported the routine use of HRT to increase longevity in postmenopausal women.
Hormone mix could cut breast cancer risk and treat symptoms of menopause
The right combination of estrogen and a selective estrogen receptor modulator (SERM), which blocks the effects of estrogen in breast tissue, could relieve menopause symptoms and cut breast cancer risk.
Breast tenderness during hormone replacement therapy linked to elevated cancer risk
Women who developed new-onset breast tenderness after starting estrogen plus progestin hormone replacement therapy were at significantly higher risk for developing breast cancer than women on the combination therapy who didn't experience such tenderness, according to a new UCLA study.
Study finds no relationship between PCR rate and race in women with breast cancer
Locally advanced breast cancer patients who received the same class of neoadjuvant chemotherapy were found to have no evidence of disease at the time of their surgery, or achieved pathological complete response, at the same rate regardless of race, according to researchers at The University of Texas M. D. Anderson Cancer Center.
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Source Naturals Phyto-Estrogen Cream, 4 oz (113.4 g) by Source Naturals Advanced liposomal delivery. Non-GMO soy. Phyto-Estrogen Cream offers some of the finest phytoestregens, renowned for use during menopause. Each ounce contains 60 mg of isoflavone phytoestrogens, along with 150 mg of pomegranate juice extract, and 100 mg of red clover extract. Micro-penetrating liposomes pass through skin layers more easily than non-liposomal creams. |
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Natural Estrogen with Pomegranate Extract, 60 caplets by Life Extension Natural Estrogen with Pomegranate Extract60 caplets Item Catalog Number: 712 In an attempt to provide aging women with the multiple health effects of the bodies’ estrogen without side effects, scientists have discovered plant extracts with estrogenic activity (phytoestrogens). Natural Estrogen with Pomegranate Extract is one answer to the concerns of maintaining healthy hormone function. A review of the published literature reveals some interesting findings about how plant-derived estrogens can provide safe and effective support for such menopausal symptoms as hot flashes. Derived from organically-grown fruit, the pomegranate extract in this formula has the same ratio of polyphenols found in the whole fruit and all the benefits one would get from the juice without the sugar, calories,... |
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Estrogen/Estriol (Bio-Identical) Fragrance Free Cream 2 oz. Pump Bottle by Radiant Laboratories - Made In USA Paraben-Free and Unscented. Menopausal Hot Flashes? Night Sweats? Trouble Sleeping? Replenish Your Estrogen Naturally and Safely. Get your life back! Estriol Has Been Used in Europe for Years. Bio-identical Hormones Are Safe and Effective. Non Prescription Bio-identical Natural Estrogen (Estriol Usp) Not to Be Confused with Phyto-estrogens. Bio-identical Hormones Are Safe for Women Help Relieve Menopause Symptoms. Estriol is not a phyto estrogen. Don't confuse phyto estrogens with pure natural estriol USP. The natural estrogen, estriol USP, is made the same way natural progesterone USP is made. Sterol analogues found in many varieties of plants are combined with specific bacteria and the resulting hormone is bio identical in chemical structure to the hormone produced by the human body.... |
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Estroven Maximum Strength - 98 Caplets by Amerifit Estroven Maximum Strength is clinically shown to reduce hot flashes and night sweats. It contains a higher level of the key black cohosh and soy isoflavones ingredients found in Estroven Regular Strength, plus additional vitamins and minerals for women's health. |
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Emerita Phytoestrogen Body Cream with Black Cohosh, 2-Ounce Tube by Emerita Peri/Menopause support. Paraben-free. Who knew a little tube of cream could change the world? In 1978 we had a revolutionary idea: that there was not enough real choice when it came to peri / menopause. So we created Pro-Gest, Phytoestrogen Cream and Pers |
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The Greatest Experiment Ever Performed on Women: Exploding the Estrogen Myth, Second Edition by Barbara Seaman (Author) A Library Journal Best Consumer Health Book of 2003 and an American Library Association/Booklist Editor's Choice Book of 2003 "Barbara Seaman is the first prophet of the women's health movement and her prophecies are still coming true."-Gloria Steinem "A wake-up call to women about unquestioningly accepting doctors' orders."-Booklist (starred review) "Lively and impassioned . . . [Seaman] certainly makes her point."-Gina Kolata, The New York Times With the ardent tone of a close friend, Barbara Seaman draws on forty years of journalistic research to expose the "menopause industry" and shows how estrogen therapy often causes more problems-including breast cancer, heart attack, and stroke-than it cures. The Greatest Experiment Ever Performed on Women tracks the... |
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Phyto-Estrogen 60 Capsules by Gaia Herbs Provides a Natural Hormonal Balance During the Onset of Menopause Rich Natural Source of Phytoestrogens Support for the Peri-Menopause and Menopausal Years |
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Alternative Health & Herbs Remedies Female Estrogen W, progesterone, 1-Ounce Bottle by Alternative Health & Herbs Remedies Alternative Health & Herbs Remedies Female Estrogen W, progesterone, promotes hormonal balance, effective for women who are experiencing menopause and it does not contain hormones. |
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Estroven Dietary Supplement Caplets for Menopause, 30-Count Boxes (Pack of 2) by Estroven Dietary Supplement with Soy and Other Plants Plus Vitamins B6, E & Calcium. Naturally helps support hormonal balance. Daily dose caplets. Naturally, safely and gently provides hormonal support before, during and after menopause - because physical and psyc |
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Estrogen Revisited: Lifelong & Fearless by Donna Walters (Author) Estrogen is essential for good health and well being in women of all ages throughout their lives. I have written this book because I want to encourage women who have been on hormone replacement, like me, to consider remaining on it for life as I plan to do. For women who have been scared or hesitant to take estrogen because they are afraid of contracting breast cancer as predicted by the incorrect conclusions of the Women's Health Initiative in 2002, read this book and save your life. My doctor told me that I should stop taking estrogen because it is recommended for the shortest amount of time to control symptoms only. I have researched this issue for over a year because I want to make the right decision for me. I have decided to share my findings and experience of long term estrogen use... |
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