Family history of breast cancer does not increase risk of womb cancerNovember 01, 2002A family history of breast cancer does not increase a woman`s chances of developing womb cancer, finds a 20-year study in the Journal of Medical Genetics. Cancers of the lining of the womb (endometrium) and breast share some of the same reproductive, hormonal, and lifestyle risk factors. The evidence for a genetic link between the two types of cancer has so far been inconclusive. But a team from the US National Cancer Institute and the Uniformed Services University of the Health Sciences in Bethesda, Maryland, investigated whether women who had a family history of breast cancer were more likely to develop endometrial cancer than women with no such family history. They studied this in over 37,500 former participants of a US national breast screening programme (the Breast Cancer Detection Demonstration Project). The women were monitored for an average of almost 14 years during the study, which started in 1979 and completed in 1998. Their average age was 55 at the start of monitoring. Information was also collected on any cases of breast cancer among their first and second degree female relatives. During the study, endometrial cancer was diagnosed in 648 women. There was no evidence that breast cancer in either a first or second degree relative predisposed to the development of endometrial cancer, after taking account of influential factors, such as age, use of hormone replacement therapy, previous breast cancer diagnosis and family size. Furthermore, the development of endometrial cancer was not affected by the number of relatives who had had breast cancer, nor the age at which they had been diagnosed. But women with a first degree relative who had cancer in both breasts had a slightly increased risk of endometrial cancer. However, there was no evidence of hereditary cancer syndromes, such as early age at diagnosis or high rates of breast cancer among family members. Women who had already had breast cancer themselves were 30 per cent more likely to develop endometrial cancer, but a family history of breast cancer had no bearing on this. The authors conclude: "a family history of breast cancer does not seem to be an important endometrial cancer risk factor, although a personal history of breast cancer does increase the risk." | |||||||||||||||||||||
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Related Breast Cancer Current Events and Breast Cancer News Articles Nursing study concludes few Ontario women with invasive ovarian cancer referred for genetic testing of breast cancer genes An Ontario study of 491 women with invasive ovarian cancer found only a small proportion, 19%, were referred for genetic testing of BRCA1 and BRCA2, the breast cancer genes, which means family members are not informed of their cancer risk. Angled gantry technique reduced breast radiation exposure by 50 percent A novel angled gantry approach to coronary CT angiography reduced radiation exposure to the breast by more than 50%, according to Thomas Jefferson University researchers. HER2 levels may aid in treatment selection for metastatic breast cancer Findings published in the December 1, 2008, issue of Clinical Cancer Research, a journal of the American Association for Cancer Research, show lapatinib benefits women with HER2-positive breast cancer, while women with HER2-negative breast cancer or those who express EGRF alone derive no incremental benefit. Drop in cancer deaths tied primarily to gains in behavior and screening Improvements in behavior and screening have contributed greatly to the 13 percent decline in cancer mortality since 1990, with better cancer treatments playing a supporting role, according to new research from David Cutler of Harvard University. New breast imaging technology targets hard-to-detect cancers Breast-specific gamma imaging (BSGI) is effective in the detection of cancers not found on mammograms or by clinical exam, according to a study presented today at the annual meeting of the Radiological Society of North America (RSNA). Delays in Radiation Therapy Lead to Increased Breast Cancer Recurrence A new analysis of the National Cancer Institute's cancer registry has found that as many as one in five older women experience delayed or incomplete radiation treatment following breast-conserving surgery, and that this suboptimal care can lead to worse outcomes. New mammography technology effective in detecting breast cancer A study has found that positron emission mammography (PEM), a new technique for imaging the breast, is not affected by either breast density or a woman's hormonal status, two factors that limit the effectiveness of standard mammography and MRI at detecting cancer. New statistical model could help reduce breast-lesion biopsies A new method of characterizing breast lesions found during an MRI exam could result in fewer biopsies of benign tumors with the benefits of reduced pain and expense for patients and providers, according to a paper that will be presented today (Sunday, Nov. 30) at the annual meeting of the Radiological Society of North America (RSNA). Breast cancer treatment offers better outcome to women with implants Women with early-stage breast cancer who have undergone breast augmentation may be treated successfully with a partial-breast radiation treatment called brachytherapy, according to a study presented today at the annual meeting of the Radiological Society of North America (RSNA). Study identifies double-balloon enteroscopy as cost-effective approach for obscure GI bleeding A cost-effectiveness analysis conducted by researchers at Stanford University Hospital in Calif., shows that an initial double-balloon enteroscopy (DBE) is a cost-effective approach for patients with obscure gastrointestinal (GI) bleeding. More Breast Cancer Current Events and Breast Cancer News Articles |
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