 |
|
The Lancet Oncology (TLO) For immediate release
October 30, 2002IS PREVENTION REALLY BETTER THAN CURE?
Billions of dollars are currently being spent on the search for effective drugs that will stop disease before it happens. Advances in genetic testing are providing more opportunities to find out which diseases people are likely to be at risk of developing-but this knowledge has put huge pressure on the medical profession to come up with ways of avoiding disease altogether. This month`s leading edge questions the ethical issues involved in chemoprevention and highlights the difficulties in obtaining reliable data from chemoprevention clinical trials. It concludes: "Genetic tests have created a demand for chemoprevention that is threatening to push medicine to its limits; health services could be stretched beyond capacity because they are treating healthy people as well as the sick. To stop this snowball effect it is essential that one simple idea is kept in mind: you can spend all the money in the world on preventive medicine, but when people won't even stop smoking, can it really work?"
STOMACH CANCER - THE LATEST TARGET FOR THE 'MAGIC BULLET'
Gastrointestinal stromal tumours (GISTs) are the most recent cancer type to be targeted by the most effective new drug of recent years-imatinib mesylate. Effective treatment of GISTs has been hindered in the past by their characteristic resistance to conventional chemotherapy and persistent misclassification of these tumours in clinical studies has made pre-2000 data difficult to interpret. However, it is now known that most GISTs contain a mutation in the KIT tyrosine kinase, which means they are an ideal target for imatinib. In their review, Heikki Joensuu and colleagues discuss the recent advances in understanding of these difficult-to-treat tumours and discusses the impact of imatinib on outcome for patients with GISTs. The authors conclude that imatinib "has provided physicians with a well-tolerated and highly effective therapeutic option for a disease for which no systemic therapy existed previously".
Imatinib was heralded the "magic bullet" drug after extraordinary success in treatment of chronic myeloid leukaemia, for which it received FDA approval last year. It has also recently been granted FDA approval for the treatment of GISTs.
Other reviews:
Antisense therapy -- the time of truth
Radiation-induced tumour necrosis factor-alpha expression -- clinical application of transcriptional and physical targeting of gene therapy
Radiotherapy for cancer of the head and neck -- altered fractionation regimens
Totally implantable venous-access ports -- local problems and extravasation injury
Lancet
Gastrointestinal stromal tumours (GISTs) are the most recent cancer type to be targeted by the most effective new drug of recent years-imatinib mesylate. Effective treatment of GISTs has been hindered in the past by their characteristic resistance to conventional chemotherapy and persistent misclassification of these tumours in clinical studies has made pre-2000 data difficult to interpret. However, it is now known that most GISTs contain a mutation in the KIT tyrosine kinase, which means they are an ideal target for imatinib. In their review, Heikki Joensuu and colleagues discuss the recent advances in understanding of these difficult-to-treat tumours and discusses the impact of imatinib on outcome for patients with GISTs. The authors conclude that imatinib "has provided physicians with a well-tolerated and highly effective therapeutic option for a disease for which no systemic therapy existed previously".
Imatinib was heralded the "magic bullet" drug after extraordinary success in treatment of chronic myeloid leukaemia, for which it received FDA approval last year. It has also recently been granted FDA approval for the treatment of GISTs.
Other reviews:
Antisense therapy -- the time of truth
Radiation-induced tumour necrosis factor-alpha expression -- clinical application of transcriptional and physical targeting of gene therapy
Radiotherapy for cancer of the head and neck -- altered fractionation regimens
Totally implantable venous-access ports -- local problems and extravasation injury
Lancet
Cancer Current Events and Cancer News RSSMenopause-cardiology consensus statement on cardiovascular disease and on HRT
A menopause-cardiology consensus statement has called for direct action to prevent cardiovascular disease (CVD) in menopausal women. The statement also concludes that there is little evidence of increased CVD risk in taking HRT.
Other Illnesses, Body Weight Do Not Explain Racial Disparities in Colon Cancer Survival, UAB Researchers Say
A new study by University of Alabama at Birmingham (UAB) researchers shows that body-mass index (BMI) and co-existing medical conditions (co-morbidity) do not explain the decreased survival observed among African-Americans compared to Caucasians who also have colon cancer.
Multiple health concerns surface as winter, vitamin D deficiences arrive
A string of recent discoveries about the multiple health benefits of vitamin D has renewed interest in this multi-purpose nutrient, increased awareness of the huge numbers of people who are deficient in it, spurred research and even led to an appreciation of it as "nature's antibiotic."
AIDS research reveals a lack of family-planning programs in Uganda
University of Alberta graduate student Jennifer Heys wants to make her message clear: there needs to be more education in Ugandan communities about contraception.
Possible Link Studied Between Childhood Abuse and Early Cellular Aging
Children who suffer physical or emotional abuse may be faced with accelerated cellular aging as adults, according to new research from Butler Hospital and Brown University.
Rare pancreatic cancer patients may live longer when treated with radiation therapy
Radiation therapy is effective in achieving local control and palliation in patients with pancreatic neuroendocrine tumors (PNTs), despite such tumors being commonly considered resistant to radiation therapy.
Researchers Identify Role of Gene in Tumor Development, Growth and Progression
Virginia Commonwealth University Massey Cancer Center and VCU Institute of Molecular Medicine researchers have identified a gene that may play a pivotal role in two processes that are essential for tumor development, growth and progression to metastasis.
Saving the single cysteine: new antioxidant system found
We've all read studies about the health benefits of having a life partner. The same thing is true at the molecular level, where amino acids known as cysteines are much more vulnerable to damage when single than when paired up with other cysteines.
Gene mismatch influences success of bone marrow transplants
A commonly inherited gene deletion can increase the likelihood of immune complications following bone marrow transplantation, an international team of researchers reports in the November 22 advance online issue of Nature Genetics.
Cancer metabolism discovery uncovers new role of IDH1 gene mutation in brain cancer
Agios Pharmaceuticals today announced that its scientists have established, for the first time, that the mutated IDH1 gene has a novel enzyme activity consistent with a cancer-causing gene, or oncogene.
More Cancer Current Events and Cancer News Articles
 |
Anticancer: A New Way of Life (Thorndike Nonfiction) by David Servan-Schreiber (Author) The New York Times bestseller takes us on an empowering journey and changes the way we think about fighting cancer David Servan-Schreiber's story of his journey from cancer patient to health combines memoir with a clear scientific explanation of what makes cancer cells thrive and what inhibits them. Anticancer is filled with easy to understand charts and diagrams and a sixteen-page color "Anticancer Action" insert that enables readers to make small but essential changes in lifestyle and diet. Your body knows how to fight cancer, says Servan-Schreiber, and you have to help it with nutrition, physical exercise, stress management, and avoiding environmental toxins. Anticancer enables people living with cancer to adopt a proactive attitude to living, even thriving, with cancer and... |
 |
Cancer: 50 Essential Things to Do: Third Edition by Greg Anderson (Author) The ground-breaking classic guide to surviving cancer—now completely updated! Revised and updated for the first time since 1999, this invaluable guide to cancer recovery offers an easily accessible plan for patients and family members. Written by a cancer survivor, the book is an inspiring, action-oriented roadmap for those who choose to adopt a stance of hope and take charge of their diagnosis. With penetrating insights that bring together more than two decades of scientifically supported research and experience, Anderson reveals a step-by-step holistic action plan that has been successfully employed by hundreds of thousands of cancer patients worldwide. Anderson’s message is: “You must not simply treat illness, you must also create wellness—physically,... |
 |
Beating Cancer with Nutrition, book with CD by Patrick Quillin (Author) Beating Cancer with Nutrition. Sugar feeds Cancer: diet and supplements can starve tumors· Nutrition makes chemo and radiation more toxic to the tumor while protecting the patient. Nutrition changes underlying causes of cancer, improving outcome for cancer patients regardless of other therapies. Why Beating Cancer with Nutrition is unique: The book was developed after working with over 500 cancer patients and organizing 3 international symposiums on the subject. The information contained in BCN is both scientifically backed with references and clinically proven in the hospital with patients. This information helps cancer patients to improve quality and quantity of life. BCN had been translated into Japanese and Chinese and is being translated into Korean. BCN had become a home study... |
 |
The Biology of Cancer HB by Robert A. Weinberg (Author) The Biology of Cancer is a new textbook for undergraduate and graduate biology students as well as medical students studying the molecular and cellular bases of cancer. The book presents the principles of cancer biology in an organized, cogent, and in-depth manner. The clarity of writing and the lucid full-color art program make the book accessible and engaging. The information unfolds through the presentation of key experiments which give readers a sense of discovery and provides insights into the conceptual foundation underlying modern cancer biology. The Biology of Cancer synthesizes the findings of three decades of recent cancer research and proposes a conceptual framework from which to teach about these discoveries. It provides the necessary structure, organization, and... |
|
Wildfox The Cancer Tee,T-shirts for Women, One Size,White by Wildfox Wildfox The Cancer Tee,T-shirts for Women: One Size Fits Most Oversized loose-fit tee with screen print on front; 100% cotton. By Wildfox | |
 |
Cancer: Step Outside the Box by Ty M. Bollinger (Author) “My hat’s off to this author. What an informative, thorough, accurate life-saving read. It's all there - just bring your highlighter and prepare to be enlightened” says Pam Hoeppner, breast cancer survivor who cured her cancer using Protocel, a treatment outlined in this book. With satisfied readers in over 50 countries world wide, Ty Bollinger’s “Cancer: Step Outside the Box” is a roadmap to successfully treating cancer and regaining your health! The fourth edition, published in May of 2009, is chock full of the most effective, non-toxic cancer treatments in the world. Truth be told, there are many potent and well-proven alternative strategies for preventing and treating cancer... without surgery, chemotherapy, or radiation (the “Big 3”). Inside this... |
 |
What to Eat if You Have Cancer (revised): Healing Foods that Boost Your Immune System by Maureen Keane (Author), Daniella Chace (Author) Fuel your body to fight cancer Cancer and cancer treatment take a toll on your body, but you can help make cancer treatment more effective and reduce its unpleasant side effects with good nutrition. What to Eat if You Have Cancer presents the best foods to fight cancer and suggests ways to keep your body strong--knowledge you need to take control of your health. A vital resource for cancer patients, this revised edition contains new recipes, new menus, and the latest research on cancer and nutrition. With the help of What to Eat if You Have Cancer, you will learn The foods to eat and the foods to avoid in your fight with cancer The proper use of supplements in nutrition therapy How to create personalized meal plans to... |
 |
When Someone You Love Has Cancer: A Guide to Help Kids Cope (Elf-Help Books for Kids) by Alaric Lewis (Author), R. W. Alley (Illustrator) |
![10 Pack of i[2]y Stupid Cancer Wristbands](http://ecx.images-amazon.com/images/I/31ru5i5U21L._SL160_.jpg) |
10 Pack of i[2]y Stupid Cancer Wristbands by I'm Too Young For This! Cancer Foundation Show your support for i[2]y and the Stupid Cancer Movement by Giving Cancer the Bird. Seventy thousand Americans between 15 and 39 years old are diagnosed with cancer every year one every eight minutes. Unlike every other age group, there has been no improvement in 5-year survival rates for young adults in the past 30 years. This is not OK! It's time for survivors in their teens, 20s and 30s to have their voices heard. Give cancer the bird and join the fight for the next generation of survivors. Stupid Cancer! Survivors Rule! 100% of all proceeds benefit the I'm Too Young For This! Cancer Foundation and it's life saving mission to support young adults with stupid cancer. i[2]y Stupid Cancer Wristbands come in packs of 10 wristbands so you and your friends can spread the word. |
 |
Cancer-Free: Your Guide to Gentle, Non-toxic Healing (Third Edition) by Bill Henderson (Author) "If you love your stricken one, this is your Bible." said Denzel Koh of Brisbane, Australia after he healed his daughter's cancer using the information in a previous edition of this book. A cancer diagnosis always causes fear. All of us have seen relatives and friends destroyed by conventional cancer treatment. Now, thanks to books like this one and the Internet, you can quickly learn what you need to know. You can heal the cancer using natural, non-toxic substances that work. What you need is a guide to cut through the overwhelming jungle of information. This book provides that guide. The information in it has been refined over eight years using feedback from real cancer survivors about what worked for them. The author has counseled hundreds of cancer... |
| © 2009 BrightSurf.com |