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Moulds increase severity of asthma
August 21, 2002Severe asthma in adults may be associated with sensitivity to airborne moulds rather than pollens, finds a study in this week's BMJ.
Researchers used data from 1,132 people with asthma from the European Community respiratory health survey to access whether the severity of asthma is associated with sensitisation to airborne moulds rather than to other allergens, such as pollens and cats.
Sensitisation to moulds was significantly associated with severity of asthma, but the team found no association between severity of asthma and sensitisation to pollens or cats.
The small size of fungal spores may allow them to reach the lower airways, suggest the authors. Unlike pollens, moulds are also present through the year with increase in the spore counts during the autumn months. Furthermore, the level of mould exposure is probably greater because the exposure occurs indoors rather than outdoors and people spend most of their time indoors.
Those people with asthma who are sensitised to airborne moulds should be educated to pay careful attention to symptoms and comply with treatment, particularly during the seasonal increase in mould spore counts, say the authors.
Patients should also be encouraged to decrease exposure by avoiding indoor conditions that facilitate the growth of moulds - for example, by better ventilation and by decreasing dampness, they conclude.
British Medical Journal (BMJ)
The small size of fungal spores may allow them to reach the lower airways, suggest the authors. Unlike pollens, moulds are also present through the year with increase in the spore counts during the autumn months. Furthermore, the level of mould exposure is probably greater because the exposure occurs indoors rather than outdoors and people spend most of their time indoors.
Those people with asthma who are sensitised to airborne moulds should be educated to pay careful attention to symptoms and comply with treatment, particularly during the seasonal increase in mould spore counts, say the authors.
Patients should also be encouraged to decrease exposure by avoiding indoor conditions that facilitate the growth of moulds - for example, by better ventilation and by decreasing dampness, they conclude.
British Medical Journal (BMJ)
Asthma Current Events and Asthma News RSSJohns Hopkins researchers track down protein responsible for chronic rhinosinusitis with polyps
A protein known to stimulate blood vessel growth has now been found to be responsible for the cell overgrowth in the development of polyps that characterize one of the most severe forms of sinusitis, a study by Johns Hopkins researchers suggests.
Ancestry attracts, but love is blind
People preferentially marry those with similar ancestry, but their decisions are not necessarily based on hair, eye or skin colour.
Common plastics chemicals linked to ADHD symptoms
Phthalates are important components of many consumer products, including toys, cleaning materials, plastics, and personal care items.
Asthma a significant risk factor for complications in children with H1N1
A new study on pediatric H1N1 influenza admissions has found that asthma is a significant risk factor for severe disease in children with pandemic H1N1 compared with the seasonal flu.
Mother's Depression a Risk Factor in Childhood Asthma Symptoms, Study Suggests
Asthma symptoms can worsen in children with depressed mothers, according to research from Johns Hopkins Children's Center published online in the Journal of Pediatric Psychology.
Sweet -- sugared polymer a new weapon against allergies and asthma
Scientists at Johns Hopkins and their colleagues have developed sugar-coated polymer strands that selectively kill off cells involved in triggering aggressive allergy and asthma attacks.
Pivotal study for PSD502 -- the first potential treatment for premature ejaculation
At the annual meeting of the Sexual Medicine Society of North America (SMSNA), Inc. in San Diego, Sciele Pharma, Inc., a Shionogi Company and Plethora Solutions Limited, a wholly owned subsidiary of Plethora Solutions Holdings PLC ("Plethora" - AIM:PLE)., today presented data from its second positive pivotal study of PSD502 for the treatment of premature ejaculation (PE).
Aileron collaborates study in Nature: Stapled peptides inhibit Notch1 transcription factor
This research validates the potential for Stapled Peptides to modulate key intracellular biological targets, such as transcription factors, that have not been addressable with current small molecule or biologic drug modalities.
Women with asthma feel worse
Women with asthma are more anxious, find it harder to sleep and are more tired during the day than their male counterparts, but nevertheless tend to be better at following their treatment.
Poll: Many parents, high-priority adults who tried to get H1N1 vaccine unable to get it
A new national poll from Harvard School of Public Health (HSPH) researchers found that a majority of adults who tried to get the H1N1 vaccine for themselves or their children have been unable to do so.
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