HRT may prevent endometrial cancerJuly 31, 2002The long-term use of hormone replacement therapy (HRT) does not increase the risk of endometrial cancer and may even protect the endometrium (the lining of the uterus) from the disease, concludes a study in this week's BMJ. In one of the largest long-term studies of its kind researchers from across the UK collected data from 534 postmenopausal women. Before the study began, 364 of the women had taken oestrogen and progestogen hormone replacement therapy in which the two hormones were given sequentially, 164 had not used hormone replacement therapy and 10 had taken oestrogen only hormone replacement therapy. The women were placed on a course of continuous combined HRT. Biopsy samples were then taken from the women before they started to take the combined HRT, after nine months, and between 24-36 months and at the end of the five year study. Before the research began, 21 women were noted as having abnormal endometrium, which when associated with other cellular changes can be an early sign of cancer, but following nine months of continuous combined HRT, the endometrium had reverted to normal. No cases of endometrial cancer developed during the study. Women who take daily combined HRT may actually be better protected against endometrial cancer than women who do not use any form of hormone replacement therapy, they conclude. British Medical Journal (BMJ) |
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| Related Estrogen Current Events and Estrogen News Articles Heart and bone damage from low vitamin D tied to declines in sex hormones Researchers at Johns Hopkins are reporting what is believed to be the first conclusive evidence in men that the long-term ill effects of vitamin D deficiency are amplified by lower levels of the key sex hormone estrogen, but not testosterone. Fertility procedures need not delay breast cancer treatment for younger women A new study published in the November issue of the Journal of the American College of Surgeons shows that breast cancer patients under 40 years old who undergo fertility preservation do not face a significant delay in the treatment of their disease when their care is coordinated in a timely fashion. Coffee break: Compound brewing new research in colon, breast cancer A compound in coffee has been found to be estrogenic in studies by Texas AgriLife Research scientists. Mayo researchers find robotic repair for vaginal prolapse has significant benefits New Mayo Clinic research has found that robotic surgery for vaginal prolapse dramatically reduces patient hospital stay and recovery time. Estrogen therapy likely must be given soon after menopause to provide stroke protection For estrogen replacement to provide stroke protection, it likely must be given soon after levels drop because of menopause or surgical removal of the ovaries, scientists report in the Journal of Neuroscience. Oral contraceptives may benefit women with asthma New research shows that during natural menstrual cycles, women with asthma who were not taking oral contraceptives (OC) had lower exhaled nitric oxide levels (eNO), a marker of airway inflammation associated with asthma, than women who were taking OC. Study shows hormone replacement therapy decreases mortality in younger postmenopausal woman Hormone replacement therapy (HRT) to treat menopausal estrogen deficiency has been in widespread use for over 60 years. Several observational studies over the years showed that HRT use by younger postmenopausal women was associated with a significant reduction in total mortality; available evidence supported the routine use of HRT to increase longevity in postmenopausal women. Hormone mix could cut breast cancer risk and treat symptoms of menopause The right combination of estrogen and a selective estrogen receptor modulator (SERM), which blocks the effects of estrogen in breast tissue, could relieve menopause symptoms and cut breast cancer risk. Breast tenderness during hormone replacement therapy linked to elevated cancer risk Women who developed new-onset breast tenderness after starting estrogen plus progestin hormone replacement therapy were at significantly higher risk for developing breast cancer than women on the combination therapy who didn't experience such tenderness, according to a new UCLA study. Study finds no relationship between PCR rate and race in women with breast cancer Locally advanced breast cancer patients who received the same class of neoadjuvant chemotherapy were found to have no evidence of disease at the time of their surgery, or achieved pathological complete response, at the same rate regardless of race, according to researchers at The University of Texas M. D. Anderson Cancer Center. More Estrogen Current Events and Estrogen News Articles |
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