Engineering to protect brittle bonesJune 19, 2002Leeds University engineer Dr Ruth Wilcox, 27, is on a mission - to help people with the brittle bone disease osteoporosis. She has just won a Post-Doctoral Research Fellowship from the Royal Academy of Engineering, starting 1 August, which will enable her to devote the next five years of her research to improving treatment of patients with osteoporosis and other painful bone disorders. Ruth's main focus is to optimise a technique called percutaneous vertebroplasty (PVP), which can be used to treat vertebral compression fractures, suffered by many elderly people with osteoporosis. PVP involves injecting special bone cement into the vertebrae of the spine to stabilise them - it is minimally invasive and therefore less traumatic for elderly patients. The procedure has become popular in the US as it is reasonably cheap to perform but is still only rarely used in the UK. It could also potentially be used to treat patients with spinal trauma and pelvic fractures. "I want to optimise the bone cements that we're using and develop a new range of cements specifically for this technique," says Ruth. "It's very exciting - new hydroxyapatite-forming materials are being developed that actually encourage bone repair. We might even be able to use bone cement to manage tumours by incorporating slow-release drugs into the cement." "Our School has a global reputation in medical engineering but spinal biomechanics is not an area in which it has traditionally operated," says Professor Philip Gaskell, Head of Leeds University's School of Mechanical Engineering. "It is to Ruth's credit, and with her energy, that this field has developed into one of growing national and international significance." Ruth's interest in engineering started with a Year in Industry placement at the Rutherford Appleton Laboratory, followed by a Masters degree in engineering science from Oxford University. She studied for her PhD in burst fracture biomechanics at Leeds University, during which she won several prizes for research and presentation from the Scoliosis Research Society and the British Orthopaedic Research Society. | |||||||||||||||||||||
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Related Osteoporosis Current Events and Osteoporosis News Articles CT colonography offers 1-stop screening for cancer and osteoporosis New research reveals that computed tomography (CT) colonography, also known as virtual colonoscopy, has the potential to screen for two diseases at once-colorectal cancer and osteoporosis, both of which commonly affect adults over age 50. Adiponectin is a metabolic link between obesity and bone mineral density Researchers at the University of Toronto, Faculty of Medicine, Toronto, Canada, have discovered that adiponectin, a protein secreted from adipocytes, is a metabolic link that can explain, in part, the known positive relationship between obesity and both bone mineral density and reduced susceptibility to fractures. Study identifies causes of bone loss in breast cancer survivors Osteoporosis is a growing concern among breast cancer survivors and their doctors, because certain cancer drugs can cause bone loss. New CT technology shows anorexia impairs adolescent bone development Children and teenagers with even mild cases of anorexia exhibit abnormal bone structure, according to a new study appearing in the December issue of Radiology and presented at the annual meeting of the Radiological Society of North America (RSNA). Adalimumab may reduce health-care costs for Crohn's disease patients Inflammatory bowel disease (IBD) is a term that refers to both ulcerative colitis (UC) and Crohn's disease (CD). IBD occurs most frequently in people in their late teens and twenties. There have been cases in children as young as two years old and in older adults in their seventies and eighties; men and women have an equal chance of getting the disease. Healthy bones program reduces hip fractures by 37 percent Proactive measures can reduce hip fracture rates by an average of 37.2 percent -- and as much as 50 percent -- among those at risk, according to a study conducted by Kaiser Permanente Southern California. The study was published online on November 3 by The Journal of Bone & Joint Surgery, a peer-reviewed journal. Study: Elderly Women Can Increase Strength But Still Risk Falls Elderly women can increase muscle strength as much as young women can, a new study from the University of New Hampshire finds, indicating that decline in muscle function is less a natural part of the aging process than due to a decline in physical activity. Heart failure patients have higher risk of fractures Heart failure patients are at higher risk for fractures, including debilitating hip fractures, than other heart patients and should be screened and treated for osteoporosis, Canadian researchers reported in Circulation: Journal of the American Heart Association. Vitamin K does not stem BMD decline in postmenopausal women with osteopenia In a randomized controlled trial called the "Evaluate the Clinical use of vitamin K Supplementation in Postmenopausal Women with Osteopenia" (ECKO) trial, Angela Cheung and colleagues at the University of Toronto found that a high dose daily vitamin K1 supplement did not protect against age-related bone mineral density (BMD) decline. Vitamin D deficiency may be more common in Parkinson's disease patients Individuals with Parkinson's disease appear more likely to be vitamin D deficient than healthy adults of the same age or patients with Alzheimer's disease, according to a report in the October issue of Archives of Neurology, one of the JAMA/Archives journals. More Osteoporosis Current Events and Osteoporosis News Articles |
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