Oestrogen may be associated with virus (HPV) infection implicated in cervical cancerJune 17, 2002The female hormone oestrogen may have a role in HPV viral infection, strains of which are implicated in cervical cancer, shows research in Sexually Transmitted Infections. Human papillomavirus (HPV) infection is a common genital infection seen most often in young women and adolescents. There are often no visible signs of infection. Researchers tested 175 sexually active women for HPV infection during routine examinations at a sexual health clinic. The women were all aged between 14 and 44. Over half were younger than 25. They also investigated how many oestrogen receptors - cells that are specifically activated by the female hormone - were present in the neck of the womb (cervix). The women also completed a questionnaire, detailing their sexual and menstrual histories. Four out of 10 women tested positive for HPV, mostly HPV 16, the strain linked to cervical cancer. Six women had two strains, and one had three. The younger the woman, the greater was her risk of infection. But starting sex at an early age was not a high risk factor for the infection, the research showed. Almost all the women with HPV infection had detectable levels of oestrogen receptors. Every 10 per cent increase in receptor numbers tripled the likelihood of HPV infection. Clearly, say the authors, younger women will have higher oestrogen levels than older women, but there was no obvious association between menstrual cycle - at certain times of which circulating oestrogen levels are higher - and the numbers of oestrogen receptors detected. And the association between oestrogen receptors and HPV held for older women as well. It may be that some women are ‘biologically vulnerable’ to HPV because of the numbers of oestrogen receptors they have in their cervix, say the authors, and suggest that these receptors may in some way facilitate infection with the virus. British Medical Journal (BMJ) |
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| Related Cervical Cancer Current Events and Cervical Cancer News Articles 1 disease, not 1 demographic The Asian continent has nearly four billion people living in 47 different countries, and each of these groups has their own unique set of health issues. But when they come to the United States, they're often lumped into one large demographic: "Asian/Pacific Islander." Alternatively spliced tissue factor identified as promising new biomarker for aggressive cancers A recently discovered form of the protein that triggers blood clotting may play a key role in the molecular mechanisms leading to the growth of certain metastatic cancers, according to new research reported by an international team of scientists. M. D. Anderson redefines screening guidelines for breast, cervical and colorectal cancers Drawing on years of experience in cancer research and patient care, The University of Texas M. D. Anderson Cancer Center released today the most comprehensive, risk-based screening guidelines publicly available to date for breast, cervical and colorectal cancers. Study finds delay in follow-up among African-American women receiving abnormal breast finding A new analysis has identified a significant delay in follow-up times among African-American women after the finding of a suspicious breast abnormality. UIC study finds girls aware of HPV vaccine's benefits Contrary to concerns that the human papillomavirus vaccine might promote promiscuity, a national survey of girls and young women found that the majority of respondents did not believe the HPV vaccine protected them against other sexually transmitted infections. Scientists identify common HPV genotypes in northern India, encourage vaccination Although a wide spectrum of human papillomavirus is seen across the population of India, HPV-16 and HPV-18 are the most common types and a vaccination targeting these types could eliminate 75 percent of the cervical cancers in the region. Vaccinating boys against human papillomavirus not cost-effective Persistent infection with high-risk types of human papillomavirus (HPV), a sexually transmitted virus, is known to be a cause of cervical cancer. Vaccination and testing for the human papilloma virus could eradicate cervical cancer Cervical cancer could be eradicated within the next 50 years if countries implement national screening programmes based on detection of the human papilloma virus (HPV), which causes the disease, together with vaccination programmes against the virus, according to a cervical cancer screening expert. Targeted heat therapy offers new standard treatment option for soft tissue sarcoma Patients with soft-tissue sarcomas at high risk of spreading were 30% more likely to be alive and cancer free almost three years after starting treatment if their tumours were heated at the time they received chemotherapy, according to new research. Even in a safety net health system, colorectal cancer screening disparities remain Colorectal cancer screening rates are much lower among those in a safety net health system compared to the national average, and the number one predictor of screening is a combination of regular visits and insurance access. More Cervical Cancer Current Events and Cervical Cancer News Articles |
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