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No evidence that MMR vaccine is associated with autism or bowel disease
June 11, 2002There is no evidence that MMR or single measles vaccines are associated with autism or inflammatory bowel disease, researchers announced today.
Their conclusion follows the most in-depth analysis of the scientific literature to date, and provides clear reassurance for parents and health professionals regarding the safety of MMR vaccination.
Their findings will be published in Clinical Evidence, the international source of the best available evidence for effective health care, published by the BMJ Publishing Group.
Dr Anna Donald, Dr Vivek Muthu and the information scientists at Clinical Evidence have conducted a detailed search of the world's scientific literature on MMR and single measles vaccination. The highest quality studies were selected and analysed, according to explicit appraisal criteria.
They found no evidence that MMR or single measles vaccines are associated with autism or inflammatory bowel disease.
They found strong evidence that both MMR and single measles vaccination virtually eliminate risk of measles and measles complications.
They found consistent evidence that MMR and single measles vaccines are associated with small, similar risks of self limiting fever within three weeks of vaccination. However, measles itself causes acute fever in all infected children.
MMR additionally protects against mumps and rubella, which themselves cause serious complications, including death.
The authors also considered the study by Wakefield and colleagues,1 which raised the question of a possible relation between MMR and developmental disorder in 12 children with bowel symptoms.
They report that the study was retrospective (parents surveyed up to 8 years after vaccination), small; lacked a control group; and was selective in its sample. For these reasons, the authors concluded that the study "does not establish MMR as a cause of inflammatory bowel disease, autism, or developmental regression, and that its hypothesis has been satisfactorily tested by scientifically reliable studies."
British Medical Journal (BMJ)
Autism Current Events and Autism News RSSBrain's magnetic fields reveal language delays in autism
Faint magnetic signals from brain activity in children with autism show that those children process sound and language differently from non-autistic children.
Brain waves show sound processing abnormalities in autistic children
Abnormalities in auditory and language processing may be evaluated in children with autism spectrum disorder by using magnetoencephalography (MEG), according to a study presented today at the annual meeting of the Radiological Society of North America (RSNA).
M.I.N.D. Institute researchers call for fragile X testing throughout the lifespan
Writing in this week's Journal of the American Medical Association, UC Davis M.I.N.D. Institute researchers urge physicians to test for mutations of the fragile X gene in patients of all ages.
Adult brain neurons can remodel connections
Overturning a century of prevailing thought, scientists are finding that neurons in the adult brain can remodel their connections.
New molecular insight into vertebrate brain development
In the December 1st issue of G&D, Dr. Fred H. Gage (The Salk Institute for Biological Studies) and colleagues reveal a role for the Hippo signaling pathway in the regulation of vertebrate neural development, identifying new factors - and potential therapeutic targets - that may be involved in congenital brain size disorders and neurological tumor formation.
AMA journal publishes by Cornell Researchers study showing evidence of a major environmental trigger for autism
The American Medical Association journal Archives of Pediatrics & Adolescent Medicine has published a new study by researchers at Cornell University indicating evidence of an environmental trigger for autism among genetically vulnerable children.
Unusual use of toys in infancy a clue to later autism
Researchers at the UC Davis M.I.N.D. Institute have found that infants later diagnosed with autism exhibited unusual exploration of objects long before being diagnosed.
Genetic study provides new insights into molecular basis of language development
Scientists have identified the first gene that is associated with a common childhood language disorder, known as specific language impairment (SLI).
Methylmercury warning
Recent studies hint that exposure to the toxic chemicals, such as methylmercury can cause harm at levels previously considered safe.
Supercomputer provides massive computational boost to biomedical research at TGen
In less time than the blink of an eye, the Translational Genomics Research Institute's new supercomputer at Arizona State University can do operations equal to every dollar in the recent Wall Street bailout.
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