Science Current Events | Science News | Brightsurf.com
 

Energy Boost For Fatigued Cancer Patients

June 11, 2002
SWALLOWING a specially designed energy drink each day could boost cancer patients left exhausted by chemotherapy, according to research published in the British Journal of Cancer today* (Tuesday).

Fatigue is one of the most common side effects of treatment for cancer, robbing patients of the energy to perform everyday tasks and severely impairing their quality of life.

But Italian scientists have found that giving people a substance called levocarnitine - which is taken in a pineapple flavoured drink - seems to help them recover from the effects of treatment. In their study, 90 per cent of those who received the supplement recovered from their fatigue within a week.

Scientists believe many cases of fatigue - which affects 80 per cent of patients receiving chemotherapy - occur when treatment disrupts a patient's metabolism. This depletes levels of a molecule called carnitine, which is vital for providing energy to our muscles.

Lead researcher Dr Francesco Graziano, of Urbino Hospital in Italy, comments: "After chemotherapy, many patients have low levels of carnitine in their blood and we think that's one of the reasons they feel so exhausted. It seemed logical that boosting carnitine levels with a dietary supplement might restore that lost energy. Our study was the first to take this new approach to treating fatigue and the results, although preliminary, were very encouraging."

Dr Graziano and his colleagues studied 50 patients who had reported feeling fatigue during the course of their chemotherapy. They used detailed questionnaires to assess each patient's degree of fatigue and took blood samples to measure carnitine levels.

Researchers then gave patients an energy drink containing levocarnitine, which is converted to carnitine in the body. After a week of treatment, their progress was assessed.

On average, blood carnitine levels increased by 50 per cent over the course of the week. And the questionnaires revealed that 45 of the 50 patients (90 per cent) no longer felt fatigued.

Dr Graziano adds: "The quality of life of our patients improved markedly over the course of the week, and it seems likely that the improvements were a result of the supplements they were taking.

"We now need larger-scale trials, to test the extent to which the supplement can restore patients' energy levels. It could become an important way of maintaining quality of life for patients undergoing intensive treatment for cancer."

Prof Gordon McVie of Cancer Research UK, owners of the British Journal of Cancer, says: "Treating patients more effectively doesn't just mean keeping them alive for longer; it also means preserving their quality of life.

"We are getting better at reducing the side effects associated with modern drugs, but chemotherapy still robs many patients of the energy they need to live their life to the full. A simple dietary supplement to restore a patient's zip would be a valuable step forward and these initial results are certainly encouraging."

Ends

Cancer Research UK


Related Chemotherapy Current Events and Chemotherapy News Articles


The DNA damage response goes viral: A way in for new cancer treatments
Every organism--from a seedling to a president--must protect its DNA at all costs, but precisely how a cell distinguishes between damage to its own DNA and the foreign DNA of an invading virus has remained a mystery.

21-gene recurrence score and receipt of chemotherapy in patients with breast cancer
Use of the 21-gene recurrence test score was associated with lower chemotherapy use in high-risk patients and greater use of chemotherapy in low-risk patients compared with not using the test among a large group of Medicare beneficiaries, according to an article published online by JAMA Oncology.

Exploding the drug deadlock: Repurposing nitroglycerin for anti-cancer treatments
For over a century, nitroglycerin has been used medically - particularly in the treatment of angina, or chest pain.

Use of tamoxifen by young women is influenced by fertility concerns
The risk of breast cancer recurrence and mortality is decreased by endocrine therapy (ET) such as tamoxifen, but younger patients may decline it or discontinue treatment early if they are concerned about fertility, according to a study published August 24 in the JNCI: Journal of the National Cancer Institute.

FSU researcher identifies protein with promise for cancer therapy
In the second part of his lab's recent one-two punch, Florida State University researcher Daniel Kaplan said he has solved a cell division mystery in a way that will intrigue the makers of cancer-fighting drugs.

Generic heart medication shown to prolong ovarian cancer patients' survival
In a first-of-its-kind study, researchers demonstrate a benefit in overall survival among epithelial ovarian cancer (EOC) patients receiving generic heart medications known as beta-blockers.

Ductal carcinoma in situ carries a higher risk of death than previously thought
Women diagnosed with ductal carcinoma in situ (DCIS) are twice as likely to die from breast cancer compared to the general U.S. population, according to a new study led by Dr. Steven Narod.

Long distance travelers likely contributing to antibiotic resistance's spread
Swedish exchange students who studied in India and in central Africa returned from their sojourns with an increased diversity of antibiotic resistance genes in their gut microbiomes. The research is published 10 August in Antimicrobial Agents and Chemotherapy, a journal of the American Society for Microbiology.

Reducing resistance to chemotherapy in colorectal cancer by inhibition of PHD1
Scientists at VIB and KU Leuven have shown that blocking the PHD1 oxygen sensor hinders the activation of p53, a transcription factor that aids colorectal cancer (CRC) cells in repairing themselves and thus resisting chemotherapy.

Drinking coffee daily may improve survival in colon cancer patients
Regular consumption of caffeinated coffee may help prevent the return of colon cancer after treatment and improve the chances of a cure, according to a new, large study from Dana-Farber Cancer Institute that reported this striking association for the first time.
More Chemotherapy Current Events and Chemotherapy News Articles

The Chemotherapy Survival Guide: Everything You Need to Know to Get Through Treatment

The Chemotherapy Survival Guide: Everything You Need to Know to Get Through Treatment
by Judith McKay (Author), Tammy Schacher RN OCN MSN (Author)


When you're facing cancer treatment, it's easy to feel overwhelmed and alone. Between the hospital or clinic environment and the medical terminology used by doctors and health care professionals, you may feel as though you've entered a foreign country.Written by two experienced oncology nurses, this compassionate and comprehensive guide explains in plain English everything you need to know about your treatment, including what you can expect at each stage of chemotherapy and what you can do to prevent or minimize side effects. Packed with practical suggestions, nutritional advice, relaxation skills, and other techniques to help strengthen your body and calm your mind, The Chemotherapy Survival Guide is a must-have resource for anyone navigating this difficult...

Chemotherapy and Biotherapy Guidelines and Recommendations for Practice

Chemotherapy and Biotherapy Guidelines and Recommendations for Practice
by Martha Polovich (Author), MiKeala Olsen (Author), Kris Lefebvre (Author)


Order your copy of the fourth edition of the best-selling resource used by more than 101,000 healthcare professionals since 2009 and keep up-to-date on the latest chemotherapy, biotherapy, and targeted agents. This new edition of the Chemotherapy and Biotherapy Guidelines and Recommendations for Practice has been revised and updated to reflect the current procedures and practices in your specialty. You'll find that this latest edition incorporates a number of significant changes. To help you find the content and information that you need quickly and easily, the text has been reorganized and is now divided into 11 chapters ranging from an overview of cancer and cancer treatment and principles of antineoplastic therapy to post-treatment care and competencies in chemotherapy administration....

Chemo: Secrets to Thriving: From someone who's been there.

Chemo: Secrets to Thriving: From someone who's been there.
by Roxanne Brown (Author), Barbara Mastej (Contributor), John S. Link M.D. (Contributor)


The thought of chemotherapy can be overwhelming, but getting through it doesn’t have to be. Chemo: Secrets to Thriving helps lighten the load. In chronological order, step-by- step, you learn what might occur, why it happens, what you can do (with your doc’s approval), and who to contact for help. Chemo: Secrets to Thriving will be your friend, companion, and guide, giving you the resources to handle possible side effects and better manage your life during chemotherapy. Once you know the secrets in this book you may find yourself still able to enjoy life—and even thrive—while going through chemotherapy. Our endorsements aren’t from the usual celebrities, but from our celebrities: medical teams, fellow chemo travelers, and the people and places that support them.

Physicians' Cancer Chemotherapy Drug Manual 2015

Physicians' Cancer Chemotherapy Drug Manual 2015
by Edward Chu (Author), Vincent T. DeVita Jr. (Author)


Completely revised and updated for 2015, the Physicians’ Cancer Chemotherapy Drug Manual is an up-to-date guide to the latest information on standard therapy and recent advances in the field. Written by world-class experts in clinical cancer therapeutics, this essential reference provides a complete, easy-to-use catalogue of over 100 drugs and commonly used drug regimens―both on- and off-label―for the treatment of all the major cancers. SPECIAL FEATURES: • Revised to reflect rapid advances in the field, incorporating treatment strategies and new drugs like afatinib, ceritinib, ibrutinib, idelalisib, obinutuzumab, and ramucirumab. • A specific chapter focused on profiling antiemetic drugs and antiemetic treatment regimens. • Diagrams of drug structures and pathways for many of...

The Chemotherapy Diet: 5 Steps to Staying Healthy During Cancer Treatment

The Chemotherapy Diet: 5 Steps to Staying Healthy During Cancer Treatment
by Mike Herbert ND (Author), Joseph Dispenza (Contributor)


During cancer treatment, it is vitally important to stay healthy. The best way of doing that is to work with the body's own natural healing abilities. And that means, in the first place to eat right.

The Chemotherapy Diet is a practical guide to feeling good during chemo... and beyond with 100+ simple recipes, menu planning guide, and more, presented in a simple 5-step program:

Change your thinking and develop an attitude focused on healing. Detoxify with therapeutic baths to promote healing from the inside out. Eat the best foods to create a healing chemistry in your body. Supplement your diet to support the healing momentum. Exercise and rest to speed the healing process.

Chemotherapy and Radiation For Dummies

Chemotherapy and Radiation For Dummies
by Alan P. Lyss (Author), Humberto Fagundes (Author), Patricia Corrigan (Author)


An informative, compassionate guide for cancer patients and their loved ones Each year, more than 1 million people get treated for cancer, and most of these will undergo chemotherapy, radiation therapy, or both. This reassuring, optimistic guide helps people get a handle on treatment options and explains in plain English how chemotherapy and radiation therapy really work. It offers detailed advice on how to alleviate and cope with side effects-which range from hair loss to nausea to anemia-and describes how good nutrition, meditation, support groups, and other techniques and resources can help in the recovery process.

Handbook of Cancer Chemotherapy (Lippincott Williams & Wilkins Handbook Series)

Handbook of Cancer Chemotherapy (Lippincott Williams & Wilkins Handbook Series)
by Roland T. Skeel (Author), Samir N. Khlief (Author)


Skeel's Handbook of Cancer Chemotherapy combines in one place the most current rationale and specific details necessary to administer chemotherapy for most adult cancers. The handbook is a practical, diseased-focused pocket reference that emphasizes the best current medical practice as it relates to the delivery of chemotherapeutic drugs. By focusing on specific plans for treatment, the book is an invaluable resource for the daily care of cancer patients.

Healthy Eating During Chemotherapy

Healthy Eating During Chemotherapy
by Jose van Mil (Author), Christina Mackenzie-Archer (Author)


People undergoing chemotherapy often experience changes in appetite and taste. Similar problems frequently arise during radiotherapy, Another common side effect is a sore mouth, making it painful to eat. At the same time, it is vital for their recovery that patients keep their body weight up. This unique cookbook is the first of its kind, offering nutritional advice and delicious recipes to help cancer patients keep on enjoying food while fighting to get better. Devised by a chef and based on medical research, the first section of the book discusses which foods are good to eat and which are not. The second part of the book contains over 160 recipes that have been created to soothe the palate. With chapter titles like Smooth, Crispy, and Soft with a Bite, the recipes focus on the...

Questioning Chemotherapy

Questioning Chemotherapy
by Ralph W. Moss (Author)


A revealing critique of chemotherapy, this book looks objectively at chemo's successes and failures.

Physicians' Cancer Chemotherapy Drug Manual 2014 (Jones and Bartlett Series in Oncology(Physician's Cancer Chemotherapy Drug Manual))

Physicians' Cancer Chemotherapy Drug Manual 2014 (Jones and Bartlett Series in Oncology(Physician's Cancer Chemotherapy Drug Manual))
by Edward Chu (Author), Vincent T. DeVita Jr. (Author)


Completely revised and updated for 2014, the Physicians’ Cancer Chemotherapy Drug Manual 2014 is an up-to-date guide to the latest information on standard therapy and recent advances in the field. Written by world-class experts in clinical cancer therapeutics, this essential reference provides a complete, easy-to-use catalog of over 100 drugs and commonly used drug regimens―both on- and off-label―for the treatment of all the major cancers. Special features: • Revised to reflect rapid advances in the field • A specific chapter focused on profiling antiemetic drug and antiemetic treatment regimens. • Diagrams of drug structures and pathways for many of the agents. • Offers a comprehensive discussion of clinical pharmacology, special considerations, indications, and dosages....

© 2015 BrightSurf.com