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Genome of PURAC's lactic acid-producing micro-organism completed by Greenomics™
May 14, 2002PURAC and Greenomics™ (Plant Research International B.V.) announced the completion of the whole-genome sequencing of a production strain of PURAC that produces high amounts of lactic acid. Greenomics™ conducted the shotgun cloning and high quality sequencing of the genome up to a zero-gap situation. The closed genome is accompanied by an automated annotation and a functional classification of all the genes by bioinformatics tools.
The positive results obtained so far has encouraged PURAC to continue the research in this field and to collaborate further with Greenomics™ in a comparative genomics project involving another lactic acid producing strain. The collaboration is not addressed at genetic modification. The results of these genomics efforts will support PURAC's gene discovery projects, and will allow PURAC to understand these lactic acid producing microorganisms at the molecular level and to establish metabolic engineering strategies. PURAC's goal is to maintain its leading position in the development of lactic acid technologies by developing new production methods for lactic acid, resulting in new products, lower production costs and less waste.
Wageningen University and Research Centre
Genome Current Events and Genome News RSSCSHL scientists discover a new way in which epigenetic information is inherited
Hereditary information flows from parents to offspring not just through DNA but also through the millions of proteins and other molecules that cling to it.
Solar-Powered Sea Slugs Live Like Plants
The lowly sea slug, "Elysia chlorotica," may not seem like the most exciting of creatures, but don't be fooled: it behaves like a plant and is solar-powered, says a Texas A&M University biologist who has been studying these tiny creatures for the past decade and, along with collaborators from several universities, has identified a possible cause of their ability to behave like plants.
Researchers recreate SARS virus, open door for potential defenses against future strains
Researchers at the University of North Carolina at Chapel Hill and Vanderbilt University Medical Center have synthetically reconstructed the bat variant of the SARS coronavirus (CoV) that caused the SARS epidemic of 2003.
Synthetic virus supports a bat origin for SARS
SARS - severe acute respiratory syndrome - alarmed the world five years ago as the first global pandemic of the 21st century. The coronavirus (SARS-CoV) that sickened more than 8,000 people - and killed nearly 800 of them - may have originated in bats, but the actual animal source is not known.
Researchers identify new leprosy bacterium
A new species of bacterium that causes leprosy has been identified through intensive genetic analysis of a pair of lethal infections, a research team reports in the December issue of the American Journal of Clinical Pathology.
Researchers Shed Light on Evolution of Gene Regulation
Scientists at Penn State have shed light on some of the processes that regulate genes -- such as the processes that ensure that proteins are produced at the correct time, place, and amount in an organism -- and they also have shed light on the evolution of the DNA regions that regulate genes.
Stanford researchers investigate how plants adapt to climate
How many mouths does a plant need in order to survive? The answer changes depending on climate, and some of the decisions are made long before a new leaf sprouts.
Bipolar disorder genes, pathways identified by Indiana University neuroscientists
Neuroscientists at the Indiana University School of Medicine have created the first comprehensive map of genes likely to be involved in bipolar disorder.
Scientists discover new species of Ebola virus
Scientists report the discovery of a new species of Ebola virus, provisionally named Bundibugyo ebolavirus, November 21 in the open-access journal PLoS Pathogens.
Systems biology brings hope of speeding up drug development
Almost every day brings news of an apparent breakthrough against cancer, infectious diseases, or metabolic conditions like diabetes, but these rarely translate into effective therapies or drugs, and even if they do clinical development usually takes well over a decade.
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