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Outdoor Team Sports In High-Ozone Environments Could Triple Asthma Risk In Children (p 386)
January 30, 2002A US study in this week's issue of THE LANCET highlights how children playing outdoor team sports in areas of high ozone concentration could be three times more likely to develop asthma than children who do not take part in sporting activities.
Asthma is the most common chronic disease of childhood; its prevalence and incidence have been increasing in children in developed countries during the past few decades, although the causes of this epidemic remain unclear. Little is known about the effect of exposure to air pollution during exercise or time spent outdoors on the development of asthma. Rob McConnell and colleagues from Keck School of Medicine of the University of Southern California, Los Angeles, USA, investigated the relation between newly-diagnosed asthma and team sports in a population of children exposed to different concentrations and mixtures of air pollutants.
Around 3500 children (who had no history of asthma) were recruited from schools in 12 communities in southern California and were followed-up for up to 5 years. 265 children reported a new diagnosis of asthma during follow-up. Children who played three or more outdoor sports in high-ozone environments were more than three times as likely to develop asthma compared with children who did not play any sports. There was no increased risk where ozone concentrations were low. Children who spent time outside in areas with high ozone concentrations were 1.4 times more likely to develop asthma than children in areas of low ozone concentration. Other environmental pollutants- nitrogen dioxide, particulate matter, and inorganic-acid vapour-were not associated with an increased asthma risk.
Rob McConnell comments: "We conclude that the incidence of new asthma diagnoses is associated with heavy exercise in communities with high levels of ambient ozone, and that in these conditions, air pollution and outdoor exercise might contribute to development of asthma in children."
Lancet
Rob McConnell comments: "We conclude that the incidence of new asthma diagnoses is associated with heavy exercise in communities with high levels of ambient ozone, and that in these conditions, air pollution and outdoor exercise might contribute to development of asthma in children."
Lancet
Asthma Current Events and Asthma News RSSExposures to metals and diesel emissions in air linked to respiratory symptoms in children
Exposure shortly after birth to ambient metals from residential heating oil combustion and particles from diesel emissions are associated with respiratory symptoms in young inner city children.
Exposure to both traffic, indoor pollutants puts some kids at higher risk for asthma later
New research presents strong evidence that the "synergistic" effect of early-life exposure to both outdoor traffic-related pollution and indoor endotoxin causes more harm to developing lungs than one or the other exposure alone.
Johns Hopkins researchers track down protein responsible for chronic rhinosinusitis with polyps
A protein known to stimulate blood vessel growth has now been found to be responsible for the cell overgrowth in the development of polyps that characterize one of the most severe forms of sinusitis, a study by Johns Hopkins researchers suggests.
Ancestry attracts, but love is blind
People preferentially marry those with similar ancestry, but their decisions are not necessarily based on hair, eye or skin colour.
Common plastics chemicals linked to ADHD symptoms
Phthalates are important components of many consumer products, including toys, cleaning materials, plastics, and personal care items.
Asthma a significant risk factor for complications in children with H1N1
A new study on pediatric H1N1 influenza admissions has found that asthma is a significant risk factor for severe disease in children with pandemic H1N1 compared with the seasonal flu.
Mother's Depression a Risk Factor in Childhood Asthma Symptoms, Study Suggests
Asthma symptoms can worsen in children with depressed mothers, according to research from Johns Hopkins Children's Center published online in the Journal of Pediatric Psychology.
Sweet -- sugared polymer a new weapon against allergies and asthma
Scientists at Johns Hopkins and their colleagues have developed sugar-coated polymer strands that selectively kill off cells involved in triggering aggressive allergy and asthma attacks.
Pivotal study for PSD502 -- the first potential treatment for premature ejaculation
At the annual meeting of the Sexual Medicine Society of North America (SMSNA), Inc. in San Diego, Sciele Pharma, Inc., a Shionogi Company and Plethora Solutions Limited, a wholly owned subsidiary of Plethora Solutions Holdings PLC ("Plethora" - AIM:PLE)., today presented data from its second positive pivotal study of PSD502 for the treatment of premature ejaculation (PE).
Aileron collaborates study in Nature: Stapled peptides inhibit Notch1 transcription factor
This research validates the potential for Stapled Peptides to modulate key intracellular biological targets, such as transcription factors, that have not been addressable with current small molecule or biologic drug modalities.
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