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Research news from BBSRC

December 27, 2001

Beam me up an antibiotic; Turkeys give thanks for virus research; Why stressed hens lay inferior eggs; Functional genomics - it's more than just buying the kit.


*Beam me up an antibiotic*
Scientists are studying the way that bacteria eject antibiotics from their cells to help develop new drugs that could foil some of the world's biggest bacterial killers. Studying the way that membrane protein transporters, which act as "drug pumps", help bacteria resist medical treatments could help the team from the University of Glasgow develop new screening tools that will ultimately help in the development of new drugs.
Contact: Dr Adrian Walmsley, University of Glasgow, +44 0141 330 3750 a.walmsley@bio.gla.ac.uk *





*Turkeys give thanks for new virus research*
Last summer, scientists at the Institute for Animal Health discovered that a virus thought only of significance in North America had infected British turkeys. The researchers have now begun a three-year study of the virus to find out the extent of infection in the British turkey flock and look at the effect of the virus on bird welfare and mortality.
Contact: Dr Dave Cavanagh, Institute for Animal Health, 01635 578 411, dave.cavanagh@bbsrc.ac.uk *


*Why stressed hens lay inferior eggs*
Scientists think they've cracked the problem of why stressed hens lay inferior eggs. In the 20 hours it takes to make an egg, tiny amounts of protein are precisely secreted into the layers of calcium carbonate that form the eggshell. In hens that are stressed, the birds delay the laying process and these secretions become more acidic, resulting in eggs that are nutritionally OK but have a powdery 'bloom' on their surface that reduces their value. Researchers hope that this may lead to a simple stress detection method for commercial layers.
Contact: Professor Sally Solomon, Head of the Poultry Research Unit at Glasgow Veterinary School, +44 (0) 141-339 8855, s.solomon@vet.gla.ac.uk *


*Functional genomics - it's more than just buying the kit*
Investigations into river pollution, rice production and food poisoning have all been given a welcome boost by the 18-month-old Functional Genomics Laboratory at the University of Birmingham. Delegates at a recent industry-backed seminar heard how the University is providing data for a wide range of projects and contributing to one of the most dynamic fields in modern biology.
Contact: Professor Charles Penn, University of Birmingham, +44 (0)121 414 6562 C.W.Penn@bham.ac.uk *

Biotechnology and Biological Sciences Research Council (BBSRC)



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Time of day matters to thirsty trees, U of T researcher discovers
The time of day matters to forest trees dealing with drought, according to a new paper produced by a research team led by Professor Malcolm Campbell, University of Toronto Scarborough's vice-principal for research and colleagues in the department of cell and systems biology at the St. George campus.

Possible Link Studied Between Childhood Abuse and Early Cellular Aging
Children who suffer physical or emotional abuse may be faced with accelerated cellular aging as adults, according to new research from Butler Hospital and Brown University.

Scientists at UA, collaborating institutions decode maize genome
Scientists from the University of Arizona led by Arizona Genomics Institute director Rod A. Wing and from collaborating institutions have deciphered the complete genetic code of the maize plant for the first time.

Schizophrenia gene's role may be broader, more potent, than thought
UCSF scientists studying nerve cells in fruit flies have uncovered a new function for a gene whose human equivalent may play a critical role in schizophrenia.

Scientists find molecular trigger that helps prevent aging and disease
Researchers at Mount Sinai School of Medicine set out to address a question that has been challenging scientists for years: How do dietary restriction-and the reverse, overconsumption-produce protective effects against aging and disease?

UCR plant scientist's research spawns new discoveries showing how crops survive drought
Breakthrough research done earlier this year by a plant cell biologist at the University of California, Riverside has greatly accelerated scientists' knowledge on how plants and crops can survive difficult environmental conditions such as drought.

Full recovery now possible for an 'untreatable' mental illness
Patients coping with the chaos and misery of Borderline Personality Disorder now have reason for strong confidence in making major life changes through a new treatment, Schema Therapy.

Pivotal study for PSD502 -- the first potential treatment for premature ejaculation
At the annual meeting of the Sexual Medicine Society of North America (SMSNA), Inc. in San Diego, Sciele Pharma, Inc., a Shionogi Company and Plethora Solutions Limited, a wholly owned subsidiary of Plethora Solutions Holdings PLC ("Plethora" - AIM:PLE)., today presented data from its second positive pivotal study of PSD502 for the treatment of premature ejaculation (PE).

Experts: Failure to focus on farming will undermine global climate agreement and increase hunger
Alarmed by a substantial oversight in the global climate talks leading up to the United Nations Climate Change Conference in Copenhagen next month, more than 60 of the world's most prominent agricultural scientists and leaders underscored how the almost total absence of agriculture in the agreement could lead to widespread famine and food shortages in the years ahead.

Inhibition of GRK2 is protective against acute cardiac stress injuries
Inhibition of a protein known to contribute to heart failure also appears to be protective of the heart in more acute cardiac stress injury, namely ischemia reperfusion.
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